{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T14:43:40Z","timestamp":1786632220872,"version":"build-2736575974"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2017,12,29]],"date-time":"2017-12-29T00:00:00Z","timestamp":1514505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The rapidly increasing dissemination of carbapenem-resistant Enterobacteriaceae (CRE) in both humans and animals poses a global threat to public health. However, the transmission of CRE between humans and animals has not yet been well studied.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>We investigated the prevalence, risk factors, and drivers of CRE transmission between humans and their backyard animals in rural China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a comprehensive sampling strategy in 12 villages in Shandong, China. Using the household [residents and their backyard animals (farm and companion animals)] as a single surveillance unit, we assessed the prevalence of CRE at the household level and examined the factors associated with CRE carriage through a detailed questionnaire. Genetic relationships among human- and animal-derived CRE were assessed using whole-genome sequencing\u2013based molecular methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 88 New Delhi metallo-\u03b2-lactamases\u2013type carbapenem-resistant Escherichia coli (NDM-EC), including 17 from humans, 44 from pigs, 12 from chickens, 1 from cattle, and 2 from dogs, were isolated from 65 of the 746 households examined. The remaining 12 NDM-EC were from flies in the immediate backyard environment. The NDM-EC colonization in households was significantly associated with a) the number of species of backyard animals raised\/kept in the same household, and b) the use of human and\/or animal feces as fertilizer. Discriminant analysis of principal components (DAPC) revealed that a large proportion of the core genomes of the NDM-EC belonged to strains from hosts other than their own, and several human isolates shared closely related core single-nucleotide polymorphisms and blaNDM genetic contexts with isolates from backyard animals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>To our knowledge, we are the first to report evidence of direct transmission of NDM-EC between humans and animals. Given the rise of NDM-EC in community and hospital infections, combating NDM-EC transmission in backyard farm systems is needed. https:\/\/doi.org\/10.1289\/EHP5251<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1289\/ehp5251","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T09:07:26Z","timestamp":1571821646000},"source":"Crossref","is-referenced-by-count":115,"title":["Inter-host Transmission of Carbapenemase-Producing\n                    <i>Escherichia coli<\/i>\n                    among Humans and Backyard Animals"],"prefix":"10.1021","volume":"127","author":[{"given":"Jiyun","family":"Li","sequence":"first","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]},{"name":"Hunan Agricultural University College of Veterinary Medicine, , Changsha, Hunan,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenwang","family":"Bi","sequence":"additional","affiliation":[{"name":"Shandong Provincial Hospital Shandong Academy of Clinical Medicine, , Jinan, Shandong,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shizhen","family":"Ma","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoli","family":"Chen","sequence":"additional","affiliation":[{"name":"Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention , Shandong Center for Disease Control and Prevention, Jinan, Shandong,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Cai","sequence":"additional","affiliation":[{"name":"Zhejiang Agricultural and Forestry University China Australia Joint Laboratory for Animal Health Big Data Analytics, College of Animal Science and Technology, , Hangzhou,","place":["China"]},{"name":"Murdoch University Research and Innovation Office, , Murdoch,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjia","family":"He","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Schwarz","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]},{"name":"Freie Universit\u00e4t Berlin Institute of Microbiology and Epizootics, Centre for Infection Medicine, Department of Veterinary Medicine, , Berlin,","place":["Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengtao","family":"Sun","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqing","family":"Zhou","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Yin","sequence":"additional","affiliation":[{"name":"Shandong University School of Health Care Management, , Jinan,","place":["China"]},{"name":"NHC Key Laboratory of Health Economics and Policy Research (Shandong University) , Jinan,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Hulth","sequence":"additional","affiliation":[{"name":"Karolinska Institutet Department of Public Health Sciences, , Stockholm,","place":["Sweden"]},{"name":"Public Health Agency of Sweden , Stockholm,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongqiang","family":"Wang","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhangqi","family":"Shen","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaolin","family":"Wang","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Congming","family":"Wu","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lennart E.","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Link\u00f6ping University Department of Clinical and Experimental Medicine, , Link\u00f6ping,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy R","family":"Walsh","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]},{"name":"Cardiff University Department of Medical Microbiology and Infectious Disease, Division of Infection and Immunity, , Cardiff,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"B\u00f6rjesson","sequence":"additional","affiliation":[{"name":"Link\u00f6ping University Department of Clinical and Experimental Medicine, , Link\u00f6ping,","place":["Sweden"]},{"name":"National Veterinary Institute (SVA) Department of Animal Health and Antimicrobial Strategies, , Uppsala,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhong","family":"Shen","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]},{"name":"China Agricultural University Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Sun","sequence":"additional","affiliation":[{"name":"Shandong University School of Health Care Management, , Jinan,","place":["China"]},{"name":"NHC Key Laboratory of Health Economics and Policy Research (Shandong University) , Jinan,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[{"name":"China Agricultural University Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, , Beijing,","place":["China"]},{"name":"China Agricultural University Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, , Beijing,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"issue":"4","key":"2026080314120410600_micit1","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1016\/j.prevetmed.2013.12.005","article-title":"Impact of foot-and-mouth disease on pork and chicken prices in Central Luzon, Philippines","volume":"113","author":"Abao","year":"2014","journal-title":"Prev Vet Med"},{"issue":"21","key":"2026080314120410600_micit2","doi-asserted-by":"publisher","first-page":"12742","DOI":"10.1021\/es502160v","article-title":"Changes in pig production in China and their effects on nitrogen and phosphorus use and losses","volume":"48","author":"Bai","year":"2014","journal-title":"Environ Sci Technol"},{"issue":"7","key":"2026080314120410600_micit3","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.1090.000192","article-title":"ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping","volume":"4","author":"Beghain","year":"2018","journal-title":"Microb Genom"},{"key":"2026080314120410600_micit4","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.prevetmed.2016.10.004","article-title":"Presence of influenza viruses in backyard poultry and swine in El Yali wetland, Chile","volume":"134","author":"Bravo-Vasquez","year":"2016","journal-title":"Prev Vet Med"},{"key":"2026080314120410600_micit5","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.onehlt.2016.09.002","article-title":"Building bridges to operationalise one health - a Sino-Swedish collaboration to tackle antibiotic resistance","volume":"2","author":"Cars","year":"2016","journal-title":"One Health"},{"key":"2026080314120410600_micit6","unstructured":"CDC (Centers for Disease Control and Prevention)\n          . 2013. Antibiotic Resistance Threats in the United States, 2013. Atlanta, GA: CDC."},{"issue":"6","key":"2026080314120410600_micit7","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1093\/jac\/dkr082","article-title":"Emergence of NDM-1-producing Acinetobacter baumannii in China","volume":"66","author":"Chen","year":"2011","journal-title":"J Antimicrob Chemother"},{"issue":"5","key":"2026080314120410600_micit8","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1093\/molbev\/mst028","article-title":"Hierarchical and spatially explicit clustering of DNA sequences with BAPS software","volume":"30","author":"Cheng","year":"2013","journal-title":"Mol Biol Evol"},{"key":"2026080314120410600_micit9","volume-title":"Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals","author":"CLSI (Clinical and Laboratory Standards Institute)","year":"2018","edition":"4th"},{"key":"2026080314120410600_micit10","volume-title":"Performance Standards for Antimicrobial Susceptibility Testing: Twenty-Fifth Informational Supplement M100-S28","author":"CLSI","year":"2018"},{"key":"2026080314120410600_micit11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.prevetmed.2017.06.005","article-title":"Exploring the role of small-scale livestock keepers for national biosecurity-the pig case","volume":"145","author":"Correia-Gomes","year":"2017","journal-title":"Prev Vet Med"},{"issue":"10","key":"2026080314120410600_micit12","doi-asserted-by":"publisher","first-page":"2893","DOI":"10.1093\/jac\/dky240","article-title":"Antibiotic use in people and pigs: a One Health survey of rural residents' knowledge, attitudes and practices in Shandong province, China","volume":"73","author":"Dyar","year":"2018","journal-title":"J Antimicrob Chemother"},{"key":"2026080314120410600_micit13","first-page":"130","article-title":"Development of large scale pig farm in China and its impact","volume":"32","author":"Gao","year":"2015","journal-title":"Swine Ind Sci"},{"issue":"10","key":"2026080314120410600_micit14","doi-asserted-by":"publisher","DOI":"10.1289\/EHP2116","article-title":"Small-scale food animal production and antimicrobial resistance: mountain, molehill, or something in-between?","volume":"125","author":"Graham","year":"2017","journal-title":"Environ Health Perspect"},{"issue":"27","key":"2026080314120410600_micit15","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2018.23.27.1700497","article-title":"Sharing more than friendship-transmission of NDM-5 ST167 and CTX-M-9 ST69 Escherichia coli between dogs and humans in a family, Finland, 2015","volume":"23","author":"Gr\u00f6nthal","year":"2018","journal-title":"Euro Surveill"},{"key":"2026080314120410600_micit16","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.envint.2018.02.003","article-title":"Presence of antibiotic residues in various environmental compartments of Shandong province in eastern China: its potential for resistance development and ecological and human risk","volume":"114","author":"Hanna","year":"2018","journal-title":"Environ Int"},{"issue":"11","key":"2026080314120410600_micit17","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1186\/s13073-014-0090-6","article-title":"SRST2: rapid genomic surveillance for public health and hospital microbiology labs","volume":"6","author":"Inouye","year":"2014","journal-title":"Genome Med"},{"issue":"2","key":"2026080314120410600_micit18","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.cll.2017.01.005","article-title":"Carbapenem-resistant Enterobacteriaceae","volume":"37","author":"Iovleva","year":"2017","journal-title":"Clin Lab Med"},{"issue":"Pt 4","key":"2026080314120410600_micit19","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1099\/jmm.0.052555-0","article-title":"Global spread of antibiotic resistance: the example of New Delhi metallo-beta-lactamase (NDM)-mediated carbapenem resistance","volume":"62","author":"Johnson","year":"2013","journal-title":"J Med Microbiol"},{"key":"2026080314120410600_micit20","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/1471-2156-11-94","article-title":"Discriminant analysis of principal components: a new method for the analysis of genetically structured populations","volume":"11","author":"Jombart","year":"2010","journal-title":"BMC Genet"},{"issue":"12","key":"2026080314120410600_micit21","doi-asserted-by":"publisher","first-page":"1241","DOI":"10.1016\/j.cmi.2018.04.004","article-title":"Carbapenem-resistant Enterobacteriaceae in wildlife, food-producing, and companion animals: a systematic review","volume":"24","author":"K\u00f6ck","year":"2018","journal-title":"Clin Microbiol Infect"},{"issue":"3","key":"2026080314120410600_micit22","doi-asserted-by":"publisher","first-page":"e02167","DOI":"10.1128\/AAC.02167-16","article-title":"Various sequence types of Escherichia coli isolates coharboring blaNDM-5 and mcr-1 genes from a commercial swine farm in China","volume":"61","author":"Kong","year":"2017","journal-title":"Antimicrob. Agents Chemother"},{"issue":"4","key":"2026080314120410600_micit23","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.prevetmed.2014.12.006","article-title":"A description of smallholder pig production systems in eastern Indonesia","volume":"118","author":"Leslie","year":"2015","journal-title":"Prev Vet Med"},{"issue":"2","key":"2026080314120410600_micit24","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/S1473-3099(15)00424-7","article-title":"Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study","volume":"16","author":"Liu","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"2026080314120410600_micit25","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1016\/j.cmi.2017.01.013","article-title":"Extended-spectrum beta-lactamase\/AmpC- and carbapenemase-producing Enterobacteriaceae in animals: a threat for humans?","volume":"23","author":"Madec","year":"2017","journal-title":"Clin Microbiol Infect"},{"issue":"2","key":"2026080314120410600_micit26","doi-asserted-by":"publisher","first-page":"489","DOI":"10.4081\/gh.2014.38","article-title":"Evaluation of the spatial patterns and risk factors, including backyard pigs, for classical swine fever occurrence in Bulgaria using a Bayesian model","volume":"8","author":"Mart\u00ednez-L\u00f3pez","year":"2014","journal-title":"Geospat Health"},{"issue":"4","key":"2026080314120410600_micit27","doi-asserted-by":"publisher","first-page":"709","DOI":"10.4269\/ajtmh.12-0568","article-title":"Formative research on hygiene behaviors and geophagy among infants and young children and implications of exposure to fecal bacteria","volume":"89","author":"Ngure","year":"2013","journal-title":"Am J Trop Med Hyg"},{"issue":"5","key":"2026080314120410600_micit28","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.molmed.2012.03.003","article-title":"Carbapenem resistance in Enterobacteriaceae: here is the storm!","volume":"18","author":"Nordmann","year":"2012","journal-title":"Trends Mol Med"},{"issue":"7","key":"2026080314120410600_micit29","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.1093\/jac\/dku054","article-title":"The carbapenemase threat in the animal world: the wrong culprit","volume":"69","author":"Poirel","year":"2014","journal-title":"J Antimicrob Chemother"},{"issue":"1","key":"2026080314120410600_micit30","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.diagmicrobio.2010.12.002","article-title":"Multiplex PCR for detection of acquired carbapenemase genes","volume":"70","author":"Poirel","year":"2011","journal-title":"Diagn Microbiol Infect Dis"},{"key":"2026080314120410600_micit31","unstructured":"Robinson\n              TP\n            , ThorntonP, FranceschiniG, KruskaRL, ChiozzaF, NotenbaertA, et\u00a0al.\n          2011. Global Livestock Production Systems. Rome, Italy: Food and Agriculture Organization of the United Nations (FAO) and International Livestock Research Institute (ILRI)."},{"key":"2026080314120410600_micit32","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.eclinm.2018.11.003","article-title":"Emerging carriage of NDM-5 and MCR-1 in Escherichia coli from healthy people in multiple regions in China: a cross sectional observational study","volume":"6","author":"Shen","year":"2018","journal-title":"EClinicalMedicine"},{"issue":"4","key":"2026080314120410600_micit33","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02569-16","article-title":"Occurrence of blaKPC-2, blaCTX-M, and mcr-1 in Enterobacteriaceae from well water in rural China","volume":"61","author":"Sun","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"2026080314120410600_micit34","first-page":"63","article-title":"The disinfection measures of large-scale farms","volume":"31","author":"Sun","year":"2015","journal-title":"Chinese Abstracts of Animal Husbandry and Veterinary Medicine"},{"issue":"1","key":"2026080314120410600_micit35","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-017832","article-title":"Study protocol for One Health data collections, analyses and intervention of the Sino-Swedish integrated multisectoral partnership for antibiotic resistance containment (IMPACT)","volume":"8","author":"Sun","year":"2018","journal-title":"BMJ Open"},{"issue":"8","key":"2026080314120410600_micit36","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1111\/zph.12526","article-title":"Genomics of Salmonella contaminating backyard production systems reveals persistence and transmission of genetically related Salmonella on a farm basis","volume":"65","author":"Toro","year":"2018","journal-title":"Zoonoses Public Health"},{"issue":"11","key":"2026080314120410600_micit37","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1186\/s13059-014-0524-x","article-title":"The Harvest suite for rapid core-genome alignment and visualization of thousands of intraspecific microbial genomes","volume":"15","author":"Treangen","year":"2014","journal-title":"Genome Biol"},{"issue":"5","key":"2026080314120410600_micit38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037152","article-title":"Identification of New Delhi metallo-beta-lactamase 1 in Acinetobacter lwoffii of food animal origin","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"},{"key":"2026080314120410600_micit39","doi-asserted-by":"publisher","first-page":"16260","DOI":"10.1038\/nmicrobiol.2016.260","article-title":"Comprehensive resistome analysis reveals the prevalence of NDM and MCR-1 in Chinese poultry production","volume":"2","author":"Wang","year":"2017","journal-title":"Nat Microbiol"},{"key":"2026080314120410600_micit40","unstructured":"WHO (World Health Organization)\n          . 2017. WHO publishes list of bacteria for which new antibiotics are urgently. http:\/\/www.who.int\/news-room\/detail\/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed [accessed June 18 2018]."},{"issue":"2","key":"2026080314120410600_micit41","doi-asserted-by":"publisher","first-page":"e00115","DOI":"10.1128\/CMR.00115-18","article-title":"NDM metallo-beta-lactamases and their bacterial producers in health care settings","volume":"32","author":"Wu","year":"2019","journal-title":"Clin Microbiol Rev"},{"key":"2026080314120410600_micit42","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.envint.2019.03.061","article-title":"Association of colistin residues and manure treatment with the abundance of mcr-1 gene in swine feedlots","volume":"127","author":"Xia","year":"2019","journal-title":"Environ Int"},{"issue":"12","key":"2026080314120410600_micit43","doi-asserted-by":"publisher","first-page":"5046","DOI":"10.1128\/AAC.00774-09","article-title":"Characterization of a new metallo-beta-lactamase gene, blaNDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India","volume":"53","author":"Yong","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"2026080314120410600_micit44","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.ebiom.2017.04.032","article-title":"Nationwide surveillance of clinical carbapenem-resistant Enterobacteriaceae (CRE) strains in China","volume":"19","author":"Zhang","year":"2017","journal-title":"EBioMedicine"},{"issue":"3","key":"2026080314120410600_micit45","doi-asserted-by":"publisher","first-page":"223","DOI":"10.15302\/J-FASE-2015065","article-title":"Characterization of NDM-1-producing carbapenemase in Acinetobacter spp. and E. coli isolates from diseased pigs","volume":"2","author":"Zhang","year":"2015","journal-title":"Front Agr Sci Eng"}],"container-title":["Environmental Health Perspectives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/doi\/10.1289\/EHP5251\/66376225\/ehp5251.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-pdf\/doi\/10.1289\/EHP5251\/66376225\/ehp5251.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:53:03Z","timestamp":1786629183000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/evhpaz\/article-lookup\/doi\/10.1289\/EHP5251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,1]]},"references-count":45,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2019,10,23]]},"published-print":{"date-parts":[[2019,10,1]]}},"URL":"https:\/\/doi.org\/10.1289\/ehp5251","relation":{},"ISSN":["0091-6765","1552-9924"],"issn-type":[{"value":"0091-6765","type":"print"},{"value":"1552-9924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,1]]},"article-number":"107009"}}