{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:47Z","timestamp":1756425767710,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Objectives: Adrenal gland hypertrophy can be related to acute stress with abnormal adrenal function tests. It may not always need treatment. Material and methods: An acute presentation of adrenal gland hypertrophy following an abdominal emergency, with subsequent hypoadrenalism was investigated. Results: Adrenal medullary and cortical function fully recovered without treatment. Conclusions: We postulate that the adrenal glands became enlarged and hypertrophied during an acute stress event, possibly caused by acute adrenal medullary hypersecretion and subsequent cortical hyposecretion. A wait and watch policy should be followed if no other clinical symptoms and signs of adrenal disease are present. CT scan remains an important diagnostic tool.<\/jats:p>","DOI":"10.12890\/2015_000257","type":"journal-article","created":{"date-parts":[[2017,3,30]],"date-time":"2017-03-30T06:42:14Z","timestamp":1490856134000},"source":"Crossref","is-referenced-by-count":2,"title":["Acute Transient Stress Induced Adrenal Hypertrophy and Adrenal Medullary Hyperactivity"],"prefix":"10.12890","volume":"3","author":[{"given":"Vikram G","family":"Arella","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals Foundation NHS Trust, King's Mill Hospital, Sutton-in-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emily T","family":"Mudenha","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals Foundation NHS Trust, King's Mill Hospital, Sutton-in-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Okpe","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals Foundation NHS Trust, King's Mill Hospital, Sutton-in-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devaka J","family":"Fernando","sequence":"additional","affiliation":[{"name":"Sherwood Forest Hospitals Foundation NHS Trust, King's Mill Hospital, Sutton-in-Ashfield, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2015,11,17]]},"reference":[{"key":"10.12890\/2015_000257_ref1","doi-asserted-by":"crossref","unstructured":"Ulrich-Lai YM, Figueiredo HF, Ostrander MM, Choi DC, Engeland WC, Herman JP. Chronic stress induces adrenal hyperplasia and hypertrophy in a subregion-specific manner. <em>Am J Physiol Endocrinol Metab <\/em>2006;<strong>291<\/strong>:E965\u2013E973.","DOI":"10.1152\/ajpendo.00070.2006"},{"key":"10.12890\/2015_000257_ref2","doi-asserted-by":"crossref","unstructured":"Chandrasekeram S, Parker R, Mudenha E, Fernando DJS. Non-acute transient reversible adrenal insufficiency in a survivor of critical illness: a lesser-known cause of primary adrenal insufficiency. <em>EJCRIM<\/em> 2014;<strong>1<\/strong>doi:10.12890\/2014_000098.","DOI":"10.12890\/2014_000098"},{"key":"10.12890\/2015_000257_ref3","doi-asserted-by":"crossref","unstructured":"Harvey S, Phillips JG, Rees A, Hall TR. Stress and adrenal function.<em> J Exp Zool 1984<\/em>;<strong>232<\/strong>:633\u2013645.","DOI":"10.1002\/jez.1402320332"},{"key":"10.12890\/2015_000257_ref4","doi-asserted-by":"crossref","unstructured":"Xarli VT, Steale AA, Davis PJ, Buescher ES, Rios CN, Garcia-Bunnel R. Adrenal haemorrhage in the adult. <em> Medicine<\/em> 1978;<strong>57<\/strong>:211.","DOI":"10.1097\/00005792-197805000-00002"},{"key":"10.12890\/2015_000257_ref5","doi-asserted-by":"crossref","unstructured":"Harvey PW, Sutcliffe C. Adrenocortical hypertrophy: establishing cause and toxicological significance.<em> J Appl Toxicol <\/em>2010;<strong>30<\/strong>:617\u2013626.","DOI":"10.1002\/jat.1569"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/257\/496","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/257\/497","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/257\/497","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:29:55Z","timestamp":1756366195000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,17]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.12890\/2015_000257","relation":{"has-manifestation":[{"id-type":"other","id":"1-12-257-g496","asserted-by":"subject"},{"id-type":"other","id":"1-12-257-g497","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-12","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2015,11,17]]},"article-number":"4"}}