{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:57Z","timestamp":1756425777494,"version":"3.44.0"},"reference-count":7,"publisher":"SMC Media","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Objectives: To report a case of intravascular lymphoma (IVL) in a Caucasian patient who presented with anasarca as his sole clinical sign. Material and Methods: A man presented with anasarca-type oedema and fatigue. After excluding heart failure, hepatic cirrhosis, nephrotic syndrome, hypothyroidism, AL-amyloidosis and adverse drug reaction which can all cause oedema, we turned our attention to capillary permeability disorders. Results: Closer review of the bone marrow aspirate demonstrated haemophagocytic histiocytosis, while core, renal and duodenal biopsies showed a B-cell IVL. Conclusion: The differential diagnosis of anasarca, a relatively common clinical sign, should include IVL although the diagnosis may still be challenging.<\/jats:p>","DOI":"10.12890\/2016_000424","type":"journal-article","created":{"date-parts":[[2017,3,30]],"date-time":"2017-03-30T06:30:14Z","timestamp":1490855414000},"source":"Crossref","is-referenced-by-count":3,"title":["Intravascular Lymphoma as an Uncommon Cause of Anasarca"],"prefix":"10.12890","volume":"3","author":[{"given":"Eleni","family":"Mylona","sequence":"additional","affiliation":[{"name":"Fifth Department of Medicine, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Styliani","family":"Golfinopoulou","sequence":"additional","affiliation":[{"name":"Fifth Department of Medicine, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelagia","family":"Sfakianaki","sequence":"additional","affiliation":[{"name":"Fifth Department of Medicine, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kyriakopoulos","sequence":"additional","affiliation":[{"name":"Pathology Department, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Tsonis","sequence":"additional","affiliation":[{"name":"Ematology Department, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theofanis","family":"Apostolou","sequence":"additional","affiliation":[{"name":"Nephrology Department, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Vourlakou","sequence":"additional","affiliation":[{"name":"Pathology Department, Evangelismos General Hospital, Athens"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Skoutelis","sequence":"additional","affiliation":[{"name":"Evangelismos General Hospital"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2016,7,27]]},"reference":[{"key":"10.12890\/2016_000424_ref1","unstructured":"<li>Guyton AC, Hall JE. The body fluid compartments: extracellular and intracellular fluids; interstitial fluid and edema. In: Guyton AC, Hall JE, editors. Textbook of Medical Physiology. Philadelphia: WB Saunders, 1991:274\u2013285.<\/li>"},{"key":"10.12890\/2016_000424_ref2","unstructured":"<li>Nakamura S, Ponzoni M, Campo E. Intravascular large B-cell lymphoma. In: Swerdlow SH, Campo E, Harris NL, et al, editors. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC Press, 2008:252\u2013253.<\/li>"},{"key":"10.12890\/2016_000424_ref3","doi-asserted-by":"crossref","unstructured":"<li>Shimada K, Kinoshita T, Naoe T, Nakamura S. Presentation and management of intravascular large B-cell lymphoma. <em>Lancet<\/em> 2009;<strong>10<\/strong>:895\u2013902.<\/li>","DOI":"10.1016\/S1470-2045(09)70140-8"},{"key":"10.12890\/2016_000424_ref4","doi-asserted-by":"crossref","unstructured":"<li>Ferreri AJ, Campo E, Seymour JF, Willemze R, Illariucci F, Ambrosetti A, et al. Intravascular lymphoma: clinical presentation, natural history, management and prognostic factors in a series of 38 cases, with special emphasis on the \u201ccutaneous variant\u201d.<em> Br J Haematol<\/em> 2004;<strong>127<\/strong>:173\u2013183.<\/li>","DOI":"10.1111\/j.1365-2141.2004.05177.x"},{"key":"10.12890\/2016_000424_ref5","doi-asserted-by":"crossref","unstructured":"<li>Bonadies N, Baud P, Peter H-J, Buergi U, Mueller BU. A case report of Clarkson\u2019s disease: if you don\u2019t know it, you\u2019ll miss it. Eur J Intern Medicine 2006;17:363\u2013365.<\/li>","DOI":"10.1016\/j.ejim.2005.12.011"},{"key":"10.12890\/2016_000424_ref6","doi-asserted-by":"crossref","unstructured":"<li>Ponzoni M, Ferreri JM. Intravascular lymphoma: a neoplasm of \u201chomeless\u201d lymphocytes? <em>Hematol Oncol<\/em> 2006;2<strong>4<\/strong>:105\u2013112.<\/li>","DOI":"10.1002\/hon.776"},{"key":"10.12890\/2016_000424_ref7","doi-asserted-by":"crossref","unstructured":"<li>Murase T, Nakamura S, Kawauchi K, Matsuraki H, Sakai C, Inaba T, et al. An Asian variant of intravascular large B-cell lymphoma: clinical, pathological and cytogenetic approaches to diffuse large B-cell lymphoma associated with haemophagocytic syndrome. <em>Br J Haematol<\/em> 2000;<strong>111<\/strong>:826\u2013834.<\/li>","DOI":"10.1046\/j.1365-2141.2000.02426.x"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/424\/572","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/424\/573","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/424\/573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:55:36Z","timestamp":1756367736000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,27]]},"references-count":7,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.12890\/2016_000424","relation":{"has-manifestation":[{"id-type":"other","id":"1-16-424-g572","asserted-by":"subject"},{"id-type":"other","id":"1-16-424-g573","asserted-by":"subject"},{"id-type":"other","id":"1-16-424-g1185","asserted-by":"subject"},{"id-type":"other","id":"1-16-424-g1186","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-16","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2016,7,27]]},"article-number":"5"}}