{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:56:44Z","timestamp":1756385804737,"version":"3.41.2"},"reference-count":0,"publisher":"SMC Media","issue":"Vol 6 No 2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Platypnoea-orthodeoxia syndrome (POS) is an uncommon clinical entity characterized by dyspnoea and hypoxaemia induced by upright posture and relieved by recumbence. It is often associated with right-to-left shunting through a patent foramen ovale (PFO) or an atrial septal defect. We report the case of a 79-year-old woman with hypoxaemia initially attributed to a pulmonary infection but persisting after successful treatment. Being in the upright position triggered the hypoxaemia. A thoracic CT angiogram and ventilation\/perfusion lung scan excluded a pulmonary embolism, but a transoesophageal echocardiogram with a bubble test showed a PFO with a right-to-left shunt, without pulmonary hypertension. The patient underwent percutaneous closure of the PFO which led to prompt symptom relief and full functional recovery.<\/jats:p>","DOI":"10.12890\/2019_001030","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T13:52:37Z","timestamp":1621950757000},"source":"Crossref","is-referenced-by-count":0,"title":["Platypnoea-Orthodeoxia Syndrome: An Intriguing Diagnosis"],"prefix":"10.12890","author":[{"family":"V\u00e2nia Rodrigues","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Leiria, Leiria, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Tiago Gomes","sequence":"additional","affiliation":[{"name":"Dermatology Department, Centro Hospitalar de Leiria, Leiria, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Adriana Santos Silva","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Leiria, Leiria, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Rita Rocha","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Leiria, Leiria, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Ana Ferr\u00e3o","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Leiria, Leiria, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2019,2,22]]},"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"deposited":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T13:54:43Z","timestamp":1621950883000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,22]]},"references-count":0,"journal-issue":{"issue":"Vol 6 No 2","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.12890\/2019_001030","relation":{"has-manifestation":[{"id-type":"other","id":"1-42-1030-g1632","asserted-by":"subject"},{"id-type":"other","id":"1-42-1030-g1633","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-42","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2019,2,22]]},"article-number":"12"}}