{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:44:05Z","timestamp":1771055045497,"version":"3.50.1"},"reference-count":0,"publisher":"SMC Media","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Pericardial effusion represents a diagnostic challenge. Erdheim-Chester disease (ECD), though a rare cause, should be considered in the differential diagnosis. An 88-year-old woman was admitted to the hospital due to retrosternal pain, dyspnoea and constitutional symptoms. Hypoxaemic respiratory failure and increased inflammatory markers were documented. A chest x-ray revealed an increased cardiothoracic ratio. An echocardiogram showed a moderate-volume pericardial effusion, without signs of cardiac tamponade. A thoraco-abdomino-pelvic CT scan found a bilateral perirenal soft tissue halo. Perirenal mass biopsy showed diffuse infiltration by foamy histiocytes (CD68+), without IgG4, compatible with ECD. The correlation of anamnesis, radiology and histology is crucial for the diagnosis of ECD.<\/jats:p>","DOI":"10.12890\/2020_001630","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":4,"title":["Erdheim-Chester Disease: A Rare Clinical Entity"],"prefix":"10.12890","volume":"7","author":[{"given":"Margarida","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sofia","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"dos Santos","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Catarina","family":"Silva","sequence":"additional","affiliation":[{"name":"Radiology Department, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rute","family":"Morais Ferreira","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hospital Pedro Hispano, Unidade Local de Sa\u00fade de Matosinhos, Matosinhos, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,6,30]]},"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1630\/2225","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1630\/2226","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1630\/2226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T13:41:47Z","timestamp":1756474907000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1630"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,30]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001630","relation":{"has-manifestation":[{"id-type":"other","id":"1-62-1630-g2225","asserted-by":"subject"},{"id-type":"other","id":"1-62-1630-g2226","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-62","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,30]]},"article-number":"43"}}