{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T04:33:50Z","timestamp":1772598830947,"version":"3.50.1"},"reference-count":0,"publisher":"SMC Media","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and has emerged as a serious public health challenge. About 20% of NAFLD patients may have low titres (&lt;1:320) of antinuclear antibodies (ANA). However, we describe a patient with NAFLD whose ANA titre was high (&gt;1:320) on presentation. After 3 months of diet, exercise and vitamin E supplementation,the patient was symptomatically better but her ANA titre had increased (&gt;1:640). Her liver biopsy showed features of NAFLD with minimal fibrosis. High-titre ANA (&gt;1:320) positivity is rare. Our patient showed a progressive rise in ANA titre from &gt;1:320 to &gt;1:640 within 3 months even though she was improving and histology showed minimal fibrosis.<\/jats:p>","DOI":"10.12890\/2020_001714","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":3,"title":["High-Titre ANA Positivity in NAFLD: An Uncommon Presentation of a Common Disease"],"prefix":"10.12890","volume":"7","author":[{"given":"Asis","family":"Mitra","sequence":"additional","affiliation":[{"name":"Ruby General Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saswati","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Physiology, Jagannath Gupta Institute of Medical Science and Hospital, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,6,8]]},"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1714\/2177","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1714\/2178","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1714\/2178","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T13:41:49Z","timestamp":1756474909000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,8]]},"references-count":0,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001714","relation":{"has-manifestation":[{"id-type":"other","id":"1-62-1714-g2177","asserted-by":"subject"},{"id-type":"other","id":"1-62-1714-g2178","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-62","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,8]]},"article-number":"26"}}