{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T03:21:35Z","timestamp":1771644095194,"version":"3.50.1"},"reference-count":8,"publisher":"SMC Media","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>An 81-year-old patient presented to the emergency department with a dark lesion on his forehead and swelling of his left eye, 3 days after a minor forehead injury and skin laceration. He also showed singular papules on his chin, upper chest, upper arms and back, later evolving into vesicles. Polymerase-chain reaction testing of vesicle content was positive for VZV and HSV-1, confirming a diagnosis of disseminated cutaneous herpes virus infection and concomitant HSV-1 reactivation. Antiviral and antibiotic treatment was initiated for 1 week with an immediate response. This case report highlights the association of head trauma and subsequent reactivation of VZV in patients at risk. Simultaneous reactivation of HSV-1 and VZV is rare in immunocompetent patients.<\/jats:p>","DOI":"10.12890\/2020_001746","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":6,"title":["Simultaneous VZV and HSV-1 Reactivation after Minor Head Injury"],"prefix":"10.12890","volume":"7","author":[{"given":"Romina","family":"H\u00e4felfinger","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, University Hospital Basel, Switzerland and University of Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Val\u00e9rie","family":"Burgener","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, University Hospital Basel, Switzerland and University of Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Osthoff","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, University Hospital Basel, Switzerland and University of Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliska","family":"Potlukova","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, University Hospital Basel, Switzerland and University of Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,9,21]]},"reference":[{"key":"10.12890\/2020_001746_ref1","doi-asserted-by":"crossref","unstructured":"<li>Theil D, Derfuss T, Strupp M, Gilden DH, Arbusow V, Brandt T. 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Identification and characterization of 20 immunocompetent patients with simultaneous varicella zoster and herpes simplex virus infection. <em>J Eur Acad Dermatol Venereol<\/em>2008;<strong>22<\/strong>(6):722\u2013728.<\/li>","DOI":"10.1111\/j.1468-3083.2008.02587.x"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1746\/2347","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1746\/2348","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1746\/2348","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T12:17:49Z","timestamp":1756469869000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":8,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001746","relation":{"has-manifestation":[{"id-type":"other","id":"1-65-1746-g2347","asserted-by":"subject"},{"id-type":"other","id":"1-65-1746-g2348","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-65","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,21]]},"article-number":"49"}}