{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:22:00Z","timestamp":1779110520327,"version":"3.51.4"},"reference-count":0,"publisher":"SMC Media","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Thyroid storm is a rare, life-threatening condition that can be caused by various pathologies including serious conditions associated with human chorionic gonadotropin (hCG)-producing tumours. We present the case of a 17-year-old male patient with a 1-month history of dyspnoea and a 3-day history of palpitations and fever. General examination revealed a left testicular mass. Blood tests revealed ?-hCG &gt;225,000 mIU\/ml, thyroid-stimulating hormone (TSH) 0.02 IU\/ml, and thyroxine (T4) 19.07 \u00b5g\/dl. He was admitted with thyroid storm. Treatment with antithyroid drugs and chemotherapy was started, but the patient died on the third day of admission. This case highlights a rare occurrence of thyroid storm linked to testicular choriocarcinoma, and provides a necessary reminder that, in some instances, hCG at very high levels can exert a thyrotropic effect due to its molecular structure, which is similar to that of TSH.<\/jats:p>","DOI":"10.12890\/2020_001754","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":3,"title":["Thyroid Storm Associated with Testicular Choriocarcinoma"],"prefix":"10.12890","volume":"7","author":[{"given":"Julio C\u00e9sar","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, University Hospital \u201cDr. Gonzalo Vald\u00e9s\u201d, Universidad Aut\u00f3noma de Coahuila, Saltillo, Coahuila, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernesto Alfonso","family":"Ovalle-Zavala","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Universidad Aut\u00f3noma de Coahuila, Saltillo, Coahuila, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,7,2]]},"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1754\/2229","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1754\/2230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1754\/2230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T13:35:37Z","timestamp":1756474537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,2]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001754","relation":{"has-manifestation":[{"id-type":"other","id":"1-63-1754-g2229","asserted-by":"subject"},{"id-type":"other","id":"1-63-1754-g2230","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-63","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,2]]},"article-number":"45"}}