{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T18:10:12Z","timestamp":1783275012351,"version":"3.54.6"},"reference-count":17,"publisher":"SMC Media","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>SARS-CoV-2 causes blood hypercoagulability and severe inflammation resulting in an increased risk of thrombosis. Consequently, COVID-19 patients with cardiovascular disease seem to be at higher risk of adverse events. Mondor\u2019s disease is a rare, generally self-limiting, thrombosis of the penis. The pathogenesis of Mondor\u2019s disease is unknown, and it is usually diagnosed through clinical signs and with Doppler ultrasound evaluation. We describe the case of a young man with COVID-19 infection who manifested Mondor\u2019s disease.<\/jats:p>","DOI":"10.12890\/2020_001803","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":6,"title":["Mondor's Disease in SARS-CoV-2 Infection: A Case of Superficial Vein Thrombosis in the Era of COVID-19"],"prefix":"10.12890","volume":"7","author":[{"given":"Gianfranco","family":"Lessiani","sequence":"first","affiliation":[{"name":"Angiology Unit, Department of Internal Medicine, \u201cVilla Serena\u201d Hospital, Citt\u00e0 Sant\u2019Angelo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Boccatonda","sequence":"first","affiliation":[{"name":"Internal Medicine, Department of Medicine and Aging Science, \u201cG. D\u2019Annunzio\u201d University of Chieti, Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"D'Ardes","sequence":"first","affiliation":[{"name":"Internal Medicine, Department of Medicine and Aging Science, \u201cG. D\u2019Annunzio\u201d University of Chieti, Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Cocco","sequence":"first","affiliation":[{"name":"Internal Medicine, Department of Medicine and Aging Science, \u201cG. D\u2019Annunzio\u201d University of Chieti, Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Di Marco","sequence":"first","affiliation":[{"name":"Urology Unit, Department of General Surgery, \u201cVilla Serena\u201d Hospital, Citt\u00e0 Sant\u2019Angelo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosima","family":"Schiavone","sequence":"first","affiliation":[{"name":"Internal Medicine, Department of Medicine and Aging Science, \u201cG. D\u2019Annunzio\u201d University of Chieti, Chieti, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10397","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"key":"10.12890\/2020_001803_ref1","doi-asserted-by":"crossref","unstructured":"<li>Huang C. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. <em>Lancet<\/em> 2020;<strong>395<\/strong>(10223):497\u2013506. <\/li>","DOI":"10.1016\/S0140-6736(20)30183-5"},{"key":"10.12890\/2020_001803_ref2","doi-asserted-by":"crossref","unstructured":"<li>Weiss P, Murdoch DR. Clinical course and mortality risk of severe COVID-19. <em>Lancet<\/em> 2020;<strong>395<\/strong>(10229):1014\u20131015.<\/li>","DOI":"10.1016\/S0140-6736(20)30633-4"},{"key":"10.12890\/2020_001803_ref3","doi-asserted-by":"crossref","unstructured":"<li>D'Ardes D, Boccatonda A, Rossi I, Guagnano MT, Santilli F, Cipollone F, et al. COVID-19 and RAS: unravelling an unclear relationship. <em>Int J Mol Sci<\/em> 2020;<strong>21<\/strong>(8):E3003.<\/li>","DOI":"10.3390\/ijms21083003"},{"key":"10.12890\/2020_001803_ref4","doi-asserted-by":"crossref","unstructured":"<li>Levi M, Thachil J, Iba T, Levy JH. Coagulation abnormalities and thrombosis in patients with COVID-19. <em>Lancet Haematol<\/em> 2020;<strong>7<\/strong>(6):e438\u2013e440.<\/li>","DOI":"10.1016\/S2352-3026(20)30145-9"},{"key":"10.12890\/2020_001803_ref5","doi-asserted-by":"crossref","unstructured":"<li>Xiong TY, Redwood S, Prendergast B, Chen M. Coronaviruses and the cardiovascular system: acute and long-term implications. <em>Eur Heart J<\/em> 2020;<strong>41<\/strong>(19):1798\u20131800. <\/li>","DOI":"10.1093\/eurheartj\/ehaa231"},{"key":"10.12890\/2020_001803_ref6","doi-asserted-by":"crossref","unstructured":"<li>Driggin E, Madhavan MV, Bikdeli B, Chuich T, Laracy J, Biondi-Zoccai G, et al. 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Mondor's disease of penis: a forgotten disease. <em>Sex Transm Infect<\/em> 2005;<strong>81<\/strong>:480\u2013482. <\/li>","DOI":"10.1136\/sti.2004.014159"},{"key":"10.12890\/2020_001803_ref12","doi-asserted-by":"crossref","unstructured":"<li>Al-Mwalad M, Loertzer H, Wicht A, Fornara P. Subcutaneous penile vein thrombosis (penile Mondor's disease): pathogenesis, diagnosis, and therapy. <em>Urology<\/em> 2006;<strong>67<\/strong>:586\u2013588.<\/li>","DOI":"10.1016\/j.urology.2005.09.054"},{"key":"10.12890\/2020_001803_ref13","doi-asserted-by":"crossref","unstructured":"<li>Varga Z, Flammer AJ, Steiger P, Haberecker M, Andermatt R, Zinkernagel AS, et al. Endothelial cell infection and endothelitis in Covid-19. <em>Lancet<\/em> 2020;<strong>395<\/strong>(10234):1417\u20131418. <\/li>","DOI":"10.1016\/S0140-6736(20)30937-5"},{"key":"10.12890\/2020_001803_ref14","doi-asserted-by":"crossref","unstructured":"<li>Cui S, Chen S, Li X, Liu S, Wang F. Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia. <em>J Thromb Haemost<\/em> 2020;<strong>18<\/strong>(6):1421\u20131424.<\/li>","DOI":"10.1111\/jth.14830"},{"key":"10.12890\/2020_001803_ref15","unstructured":"<li>Boccatonda A, Ianniello E, D\u2019Ardes D, Cocco G, Giostra F, Borghi C, et al. Can lung ultrasound be used to screen for pulmonary embolism in patients with SARS-CoV-2 pneumonia? <em>Eur J Case Rep Intern Med<\/em> 2020;<strong>7<\/strong>(7):001748. <\/li>"},{"key":"10.12890\/2020_001803_ref16","doi-asserted-by":"crossref","unstructured":"<li>Klok FA, Kruip MJHA, van der Meer NJM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. <em>Thromb Res<\/em> 2020;<strong>191<\/strong>:145-147. doi:10.1016\/j.thromres.2020.04.013.<\/li>","DOI":"10.1016\/j.thromres.2020.04.013"},{"key":"10.12890\/2020_001803_ref17","doi-asserted-by":"crossref","unstructured":"<li>Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. 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