{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T14:10:03Z","timestamp":1756476603622,"version":"3.44.0"},"reference-count":6,"publisher":"SMC Media","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Pheochromocytoma, papillary thyroid carcinoma and hyperparathyroidism have rarely been reported together. Whether this association is coincidental or results from an unknown genetic predisposition is difficult to ascertain. We present the case of a patient who was diagnosed with pheochromocytoma, bilateral papillary thyroid carcinoma and parathyroid hyperplasia with primary hyperparathyroidism. A genetic mutation was hypothesized as the connection between these lesions. Previously described mutations were explored.<\/jats:p>","DOI":"10.12890\/2020_001818","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":0,"title":["Multiple Endocrine Neoplasia or Accidental Association?"],"prefix":"10.12890","volume":"7","author":[{"given":"Georgiana Cristina","family":"Taujan","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felicia","family":"Baleanu","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Spinato","sequence":"additional","affiliation":[{"name":"Oto-Rhino-Laryngology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Duttmann","sequence":"additional","affiliation":[{"name":"Anatomic Pathology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafik","family":"Karmali","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Iconaru","sequence":"additional","affiliation":[{"name":"Endocrinology Department, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,8,10]]},"reference":[{"key":"10.12890\/2020_001818_ref1","doi-asserted-by":"crossref","unstructured":"<li>Yang JH, Bae SJ, Park S, Park HK, Jung HS, Chung JH, et al. Bilateral pheochromocytoma associated with paraganglioma and papillary thyroid carcinoma: report of an unusual case. <em>Endocr J<\/em> 2007;<strong>54<\/strong>(2):227\u2013231.<\/li>","DOI":"10.1507\/endocrj.K06-068"},{"key":"10.12890\/2020_001818_ref2","doi-asserted-by":"crossref","unstructured":"<li>Gelato MC, Vassalotti J. Insulin-like growth factor-II: possible local growth factor in pheochromocytoma. <em>J Clin Endocrinol Metab<\/em> 1990;<strong>71<\/strong>:1168\u20131174.<\/li>","DOI":"10.1210\/jcem-71-5-1168"},{"key":"10.12890\/2020_001818_ref3","doi-asserted-by":"crossref","unstructured":"<li>Miccoli P, Minuto MN, Galleri D, D'Agostino V, Basolo F, Antonangeli L, et al. Incidental thyroid carcinoma in a large series of consecutive patients operated on for benign thyroid disease. <em>Anz J Surg<\/em> 2006;<strong>76<\/strong>(3):123\u2013126.<\/li>","DOI":"10.1111\/j.1445-2197.2006.03667.x"},{"key":"10.12890\/2020_001818_ref4","doi-asserted-by":"crossref","unstructured":"<li>Nilsson IL, Zedenius J, Yin L, Anders E. The association between primary hyperparathyroidism and malignancy: nationwide cohort analysis on cancer incidence after parathyroidectomy. <em>Endocr Relat Cancer<\/em> 2007;<strong>14<\/strong>:135\u2013140.<\/li>","DOI":"10.1677\/erc.1.01261"},{"key":"10.12890\/2020_001818_ref5","doi-asserted-by":"crossref","unstructured":"<li>Goswami S, Ghosh S. Hyperparathyroidism: cancer and mortality. <em>Indian J Endocrinol<\/em> Metab 2012;<strong>16<\/strong>(Suppl 2):S217\u2013220.<\/li>","DOI":"10.4103\/2230-8210.104042"},{"key":"10.12890\/2020_001818_ref6","doi-asserted-by":"crossref","unstructured":"<li>Rivera M, Ricarte-Filho J, Knauf J, Shaha A, Tuttle M, Fagin J, et al. Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation patterns. <em>Mod Pathol<\/em> 2010;<strong>23<\/strong>(9):1191\u20131200. <\/li>","DOI":"10.1038\/modpathol.2010.112"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1818\/2285","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1818\/2286","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1818\/2286","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T13:29:04Z","timestamp":1756474144000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1818"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,10]]},"references-count":6,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001818","relation":{"has-manifestation":[{"id-type":"other","id":"1-64-1818-g2285","asserted-by":"subject"},{"id-type":"other","id":"1-64-1818-g2286","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-64","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2020,8,10]]},"article-number":"55"}}