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The authors describe a case of endogenous hypoglycaemic hyperinsulinism, its diagnosis and treatment and the challenges of determining its aetiology.<\/jats:p>","DOI":"10.12890\/2020_001827","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":1,"title":["Asymptomatic Hyperinsulinaemic Hypoglycaemia"],"prefix":"10.12890","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7013-3664","authenticated-orcid":false,"given":"Ana","family":"Ferreira","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Serino","family":"Barbosa","sequence":"first","affiliation":[{"name":"Department of Pneumology, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita","family":"Coelho","sequence":"first","affiliation":[{"name":"Department of Anatomopathology, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia","family":"Louren\u00e7o","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"10.12890\/2020_001827_ref1","doi-asserted-by":"crossref","unstructured":"<li>Kittah NE, Vella A. Management of endocrine disease: pathogenesis and management of hypoglycemia. <em>Eur J Endocrinol<\/em> 2017;<strong>177<\/strong>(1):R37\u2013R47.<\/li>","DOI":"10.1530\/EJE-16-1062"},{"key":"10.12890\/2020_001827_ref2","doi-asserted-by":"crossref","unstructured":"<li>Challis BG, Powlson AS, Casey RT, Pearson C, Lam BY, Ma M, et al. Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management. <em>Endocr Connect<\/em> 2017;<strong>6<\/strong>(7):540\u2013548.<\/li>","DOI":"10.1530\/EC-17-0076"},{"key":"10.12890\/2020_001827_ref3","doi-asserted-by":"crossref","unstructured":"<li>Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER, et al. Evaluation and management of adult hypoglycemic disorders: an Endocrine Society clinical practice guideline. <em>J Clin Endocrinol Metab<\/em> 2009;<strong>94<\/strong>(3):709\u2013728.<\/li>","DOI":"10.1210\/jc.2008-1410"},{"key":"10.12890\/2020_001827_ref4","doi-asserted-by":"crossref","unstructured":"<li>Mart\u00edn-Tim\u00f3n I, Ca\u00f1izo-G\u00f3mez FJ. Mechanisms of hypoglycemia unawareness and implications in diabetic patients. <em>World J Diabetes<\/em> 2015;<strong>6<\/strong>(7):912\u2013926.<\/li>","DOI":"10.4239\/wjd.v6.i7.912"},{"key":"10.12890\/2020_001827_ref5","doi-asserted-by":"crossref","unstructured":"<li>Herbel G, Boyle P. Hypoglycemia: pathophysiology and treatment. <em>Endocrinol Metab Clin North Am<\/em> 2000;<strong>29<\/strong>(4):725\u2013743.<\/li>","DOI":"10.1016\/S0889-8529(05)70161-4"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1827\/2263","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1827\/2264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1827\/2264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T13:35:35Z","timestamp":1756474535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,24]]},"references-count":5,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001827","relation":{"has-manifestation":[{"id-type":"other","id":"1-63-1827-g2263","asserted-by":"subject"},{"id-type":"other","id":"1-63-1827-g2264","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-63","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2020,7,24]]}}}