{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T12:40:04Z","timestamp":1756471204309,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Background: Ischaemic stroke can be classified according to its aetiology. In cryptogenic stroke, Lambl\u2019s excrescences should be considered since they can only be detected through transesophageal echocardiography (TEE), which is not routinely performed. Case description: The authors report the case of a 63-year-old Caucasian man with two ischaemic cerebral events associated with the presence of Lambl\u2019s excrescences in the aortic valve detected with TEE. Switching antiaggregant therapy to anticoagulant therapy allowed the patient to remain asymptomatic throughout a 3-year follow-up. Conclusion: The lack of protocols for the management of cryptogenic stroke results in a delay in the identification of less frequent causes of stroke, leading to recurrent vascular events, morbidity and loss of functionality. The authors describe a patient who experienced multiple cerebral ischaemic events until the correct diagnosis was made.<\/jats:p>","DOI":"10.12890\/2020_001928","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":1,"title":["Cryptogenic Stroke and Valvular Strands"],"prefix":"10.12890","volume":"7","author":[{"given":"C\u00e1tia Castanheira","family":"Figueiredo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Sofia","family":"Rebelo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Lemos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,10,20]]},"reference":[{"key":"10.12890\/2020_001928_ref1","unstructured":"<li>Aziz F, Baciewicz FA. Lambl\u2019s excrescences: review and recommendations. <em>Tex Heart Inst J<\/em> 2007;<strong>34<\/strong>:366\u2013368.<\/li>"},{"key":"10.12890\/2020_001928_ref2","doi-asserted-by":"crossref","unstructured":"<li>Homma S, Tullio M, Sciacca R, Sacco R, Mohr J, for the PICSS Investigators. Effect of aspirin and warfarin therapy in stroke patients with valvular strands. <em>Stroke<\/em> 2004;<strong>35<\/strong>:1436\u20131442. <\/li>","DOI":"10.1161\/01.STR.0000126100.53682.a0"},{"key":"10.12890\/2020_001928_ref3","doi-asserted-by":"crossref","unstructured":"<li>Wu TY, Gerber IL, Roxburgh RH. Thrombo-embolic cerebral infarction secondary to giant Lambl's excrescence. <em>J Clin Neurosci<\/em> 2013;<strong>20<\/strong>:1632\u20134.<\/li>","DOI":"10.1016\/j.jocn.2012.08.015"},{"key":"10.12890\/2020_001928_ref4","doi-asserted-by":"crossref","unstructured":"<li>Rhee H, Choi H, Kim S, Shin W, Kim S. Acute ischemic stroke in a patient with a native valvular strand. <em>Case Rep Neurol<\/em> 2010;<strong>2<\/strong>:91\u201395.<\/li>","DOI":"10.1159\/000317117"},{"key":"10.12890\/2020_001928_ref5","doi-asserted-by":"crossref","unstructured":"<li>Roldan C, Schevchuck O, Tolstrup K, Roldan P, Macias P, Qualls C, et al. Lambl\u2019s excrescences: association with cerebrovascular disease and pathogenesis. <em>Cerebrovasc Dis<\/em> 2015;<strong>40<\/strong>(0):18\u201327. <\/li>","DOI":"10.1159\/000381906"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1928\/2404","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1928\/2405","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1928\/2405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T12:17:14Z","timestamp":1756469834000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,20]]},"references-count":5,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001928","relation":{"has-manifestation":[{"id-type":"other","id":"1-65-1928-g2404","asserted-by":"subject"},{"id-type":"other","id":"1-65-1928-g2405","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-65","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2020,10,20]]},"article-number":"30"}}