{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:05:44Z","timestamp":1756512344653,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Extraintestinal manifestations of Crohn's disease sometimes occur and can present prior to intestinal symptoms. Ocular manifestations of Crohn's disease are considered rare, with orbital myositis an even rarer manifestation with only a handful of cases reported in the literature. We present the case of a young woman who was diagnosed with orbital myositis, which was initially attributed to pseudotumor cerebri after an extensive negative work-up. Months later, the patient presented with haematochezia, and was subsequently diagnosed with Crohn's disease.<\/jats:p>","DOI":"10.12890\/2020_001964","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":4,"title":["Keep an Eye Out for Crohn\u2019s Disease: Orbital Myositis as the Initial Sign before Gastrointestinal Manifestations"],"prefix":"10.12890","volume":"7","author":[{"given":"Gilles Jadd","family":"Hoilat","sequence":"additional","affiliation":[{"name":"SUNY Upstate Medical University, Department of Medicine, Syracuse, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abinash","family":"Subedi","sequence":"additional","affiliation":[{"name":"NY Upstate Medical University, Department of Medicine, Syracuse, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad Fekredeen","family":"Ayas","sequence":"additional","affiliation":[{"name":"Ascension St. John Hospital, Department of Medicine, Detroit, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuri","family":"Ozden","sequence":"additional","affiliation":[{"name":"SUNY Upstate Medical University, Department of Gastroenterology, Syracuse, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2020,10,1]]},"reference":[{"key":"10.12890\/2020_001964_ref1","doi-asserted-by":"crossref","unstructured":"<li>Bernstein CN, Blanchard JF, Rawsthorne P, Yu N. The prevalence of extraintestinal diseases in inflammatory bowel disease: a population-based study. <em>Am J Gastroenterol<\/em> 2001;<strong>96<\/strong>(4):1116\u20131122. <\/li>","DOI":"10.1111\/j.1572-0241.2001.03756.x"},{"key":"10.12890\/2020_001964_ref2","doi-asserted-by":"crossref","unstructured":"<li>Kim DR, Kim D, Choi S, Suh YL, Yoo SY, Kim MJ, et al. Myositis as an initial presentation of ulcerative colitis before gastrointestinal symptoms. <em>Pediatr Gastroenterol Hepatol Nutr<\/em> 2020;<strong>23<\/strong>(3):297\u2013303. <\/li>","DOI":"10.5223\/pghn.2020.23.3.297"},{"key":"10.12890\/2020_001964_ref3","doi-asserted-by":"crossref","unstructured":"<li>Verma S, Kroeker KI, Fedorak RN. Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature. <em>BMC Gastroenterol<\/em> 2013;<strong>13<\/strong>:59. <\/li>","DOI":"10.1186\/1471-230X-13-59"},{"key":"10.12890\/2020_001964_ref4","unstructured":"<li>Benmiloud S, Boubbou M, Hida M. Bilateral idiopathic orbital myositis in an infant. <em>Int J Res Med<\/em> 2013;<strong>2<\/strong>:112\u2013114.<\/li>"},{"key":"10.12890\/2020_001964_ref5","doi-asserted-by":"crossref","unstructured":"<li>Harbord M, Annese V, Vavricka SR, Allez M, Barreiro-de Acosta M, Boberg KM, et al. The first European evidence-based consensus on extra-intestinal manifestations in inflammatory bowel disease. <em>J Crohns Colitis<\/em> 2016;<strong>10<\/strong>(3):239\u2013254. <\/li>","DOI":"10.1093\/ecco-jcc\/jjv213"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1964\/2364","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1964\/2365","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/1964\/2365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T12:17:35Z","timestamp":1756469855000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/1964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,1]]},"references-count":5,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.12890\/2020_001964","relation":{"has-manifestation":[{"id-type":"other","id":"1-65-1964-g2364","asserted-by":"subject"},{"id-type":"other","id":"1-65-1964-g2365","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-65","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2020,10,1]]},"article-number":"42"}}