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Material and Methods: We present the case of a patient with an oesophageal adenocarcinoma and haematemesis due to a subclavian arterio-oesophageal fistula after mediastinal radiotherapy.\u00a0 Conclusion: We discuss the rare, life-threatening condition of acute erosion of the left subclavian artery caused by an oesophageal tumour and presenting with Chiari's triad.<\/jats:p>","DOI":"10.12890\/2021_002134","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":2,"title":["Midthoracic Pain, Sentinel Arterial Haemorrhage and Exsanguination after a Symptom-Free Interval (Chiari's Triad) is Diagnostic of Arterio-Oesophageal Fistula: A Life-Threatening Cause of Gastrointestinal Bleeding"],"prefix":"10.12890","volume":"8","author":[{"given":"Andra","family":"Glodean","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic Barmelweid, Barmelweid, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rainer","family":"Grobholz","sequence":"additional","affiliation":[{"name":"Institute of Pathology, Cantonal Hospital Aarau, Aarau, Switzerland; Medical Faculty, University of Zurich, Zurich, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karim","family":"El-Hag","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic Barmelweid, Barmelweid, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mairi","family":"Ziaka","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic Barmelweid, Barmelweid, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Paul","family":"Schmid","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Clinic Barmelweid, Barmelweid, Switzerland; Medical Faculty, University of Bern, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"10.12890\/2021_002134_ref1","doi-asserted-by":"crossref","unstructured":"<li>Kamboj AK, Hoversten P, Leggett CL. Upper gastrointestinal bleeding: etiologies and management. <em>Mayo Clin Proc<\/em> 2019;<strong>94<\/strong>(4):697\u2013703.<\/li>","DOI":"10.1016\/j.mayocp.2019.01.022"},{"key":"10.12890\/2021_002134_ref2","unstructured":"<li>Chiari H. Ueber Fremdkoerperverletzung des Oesophagus mit Aortenperforation. <em>Berl Klin Wochenschr<\/em> 1914;<strong>51<\/strong>:7.<\/li>"},{"key":"10.12890\/2021_002134_ref3","doi-asserted-by":"crossref","unstructured":"<li>Saers SJ, Scheltinga MR. Primary aortoenteric fistula.<em> Br J Surg<\/em> 2005;<strong>92<\/strong>(2):143\u2013152.<\/li>","DOI":"10.1002\/bjs.4928"},{"key":"10.12890\/2021_002134_ref4","doi-asserted-by":"crossref","unstructured":"<li>Hollander JE, Quick G. Aortoesophageal fistula: a comprehensive review of the literature. <em>Am J Med<\/em> 1991;<strong>91<\/strong>(3):279\u2013287.<\/li>","DOI":"10.1016\/0002-9343(91)90129-L"},{"key":"10.12890\/2021_002134_ref5","doi-asserted-by":"crossref","unstructured":"<li>Kawakami T, Tsushima T, Omae K, Ogawa H, Shirasu H, Kito Y, et al. Risk factors for esophageal fistula in thoracic esophageal squamous cell carcinoma invading adjacent organs treated with definitive chemoradiotherapy: a monocentric case-control study. <em>BMC Cancer<\/em> 2018;<strong>18<\/strong>(1):573.<\/li>","DOI":"10.1186\/s12885-018-4486-3"},{"key":"10.12890\/2021_002134_ref6","doi-asserted-by":"crossref","unstructured":"<li>Taniguchi H, Yamazaki K, Boku N, Funakoshi T, Hamauchi S, Tsushima T, et al. Risk factors and clinical courses of chemoradiation-related arterio-esophageal fistula in esophageal cancer patients with clinical invasion of the aorta. <em>Int J Clin Oncol<\/em> 2011;<strong>16<\/strong>(4):359\u2013365.<\/li>","DOI":"10.1007\/s10147-011-0192-8"},{"key":"10.12890\/2021_002134_ref7","doi-asserted-by":"crossref","unstructured":"<li>Sivaraman SK, Drummond R. Radiation-induced aortoesophageal fistula: an unusual case of massive upper gastrointestinal bleeding. <em>J Emerg Med<\/em> 2002;<strong>23<\/strong>(2):175\u2013178.<\/li>","DOI":"10.1016\/S0736-4679(02)00488-2"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2134\/2570","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2134\/2571","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2134\/2571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:42:51Z","timestamp":1756374171000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,23]]},"references-count":7,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002134","relation":{"has-manifestation":[{"id-type":"other","id":"1-67-2134-g2570","asserted-by":"subject"},{"id-type":"other","id":"1-67-2134-g2571","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-67","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2021,2,23]]},"article-number":"10"}}