{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:10:18Z","timestamp":1756379418043,"version":"3.44.0"},"reference-count":7,"publisher":"SMC Media","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Guillain-Barr\u00e9 syndrome (GBS) is an acute inflammatory polyradiculoneuropathy. Progressive limb weakness, diminished\/absent reflexes, sensory disturbance, and variable autonomic dysfunction are its core clinical manifestations. Bifacial weakness with paraesthesias (BFP) is a rare regional variant of GBS and is characterized by simultaneous facial diplegia, distal paraesthesias and minimal or no motor weakness. The association of headache with classic GBS has been rarely reported in the literature, and has not yet been described in the BFP variant. Here we report a misleading case of BFP variant associated with severe headache and mild pleocytosis. The repetition of nerve conduction studies (NCS) was extremely beneficial in this confusing case.<\/jats:p>","DOI":"10.12890\/2021_002211","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":1,"title":["Severe Headache, Paraesthesias, Facial Diplegia and Pleocytosis: A Misleading Presentation of Guillain-Barr\u00e9 Syndrome"],"prefix":"10.12890","volume":"8","author":[{"given":"Mohamed Reda","family":"Belkhribchia","sequence":"additional","affiliation":[{"name":"Neurology Department, Hassan II Regional Hospital, Dakhla, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abderrahim","family":"Chekabab","sequence":"additional","affiliation":[{"name":"Medical Laboratory, Fourth Military Hospital, Dakhla, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"Naji","sequence":"additional","affiliation":[{"name":"Neurology Department, University Hospital Mohamed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latifa","family":"Hadrane","sequence":"additional","affiliation":[{"name":">Private Neurology Practice, Agadir, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soufiane","family":"Hassar","sequence":"additional","affiliation":[{"name":"Emergency Department, Hassan II Regional Hospital, Dakhla, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nissrine","family":"Louhab","sequence":"additional","affiliation":[{"name":"Neurology Department, University Hospital Mohamed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najib","family":"Kissani","sequence":"additional","affiliation":[{"name":"Neurology Department, University Hospital Mohamed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2021,1,29]]},"reference":[{"key":"10.12890\/2021_002211_ref1","doi-asserted-by":"crossref","unstructured":"<li>Fokke C, van den Berg B, Drenthen J, Walgaard C, van Doorn PA, Jacobs BC. Diagnosis of Guillain-Barr\u00e9 syndrome and validation of Brighton criteria. <em>Brain<\/em> 2014;<strong>137<\/strong>(Pt 1):33\u201343. <\/li>","DOI":"10.1093\/brain\/awt285"},{"key":"10.12890\/2021_002211_ref2","doi-asserted-by":"crossref","unstructured":"<li>Susuki K, Koga M, Hirata K, Isogai E, Yuki N. A Guillain-Barr\u00e9 syndrome variant with prominent facial diplegia. <em>J Neurol<\/em> 2009;<strong>256<\/strong>(11):1899\u20131905.<\/li>","DOI":"10.1007\/s00415-009-5254-8"},{"key":"10.12890\/2021_002211_ref3","doi-asserted-by":"crossref","unstructured":"<li>Wakerley BR, Yuki N. Isolated facial diplegia in Guillain-Barr\u00e9 syndrome: bifacial weakness with paresthesias. <em>Muscle Nerve<\/em> 2015;<strong>52<\/strong>(6):927\u2013932.<\/li>","DOI":"10.1002\/mus.24887"},{"key":"10.12890\/2021_002211_ref4","doi-asserted-by":"crossref","unstructured":"<li>Willison HJ, Jacobs BC, van Doorn PA. Guillain-Barr\u00e9 syndrome. <em>Lancet<\/em> 2016;<strong>388<\/strong>(10045):717\u2013727.<\/li>","DOI":"10.1016\/S0140-6736(16)00339-1"},{"key":"10.12890\/2021_002211_ref5","doi-asserted-by":"crossref","unstructured":"<li>Moulin D, Hagen N, Feasby T, Amireh R, Hahn A. Pain in Guillain\u2013Barr\u00e9 syndrome. <em>Neurology<\/em> 1997;<strong>48<\/strong>(2):328\u2013331.<\/li>","DOI":"10.1212\/WNL.48.2.328"},{"key":"10.12890\/2021_002211_ref6","doi-asserted-by":"crossref","unstructured":"<li>Farmakidis C, Inan S, Milstein M, Herskovitz S. Headache and pain in Guillain\u2013Barr\u00e9 syndrome. <em>Curr Pain Headache Rep<\/em> 2015;<strong>19<\/strong>(8):40.","DOI":"10.1007\/s11916-015-0508-x"},{"key":"10.12890\/2021_002211_ref7","doi-asserted-by":"crossref","unstructured":"<li>Kumar P, Charaniya R, Bahl A, Ghosh A, Dixit J. Facial diplegia with paresthesia: an uncommon variant of Guillain-Barre syndrome. <em>J Clin Diagn Res<\/em> 2016;<strong>10<\/strong>(7):OD01\u20132.<\/li>","DOI":"10.7860\/JCDR\/2016\/19951.8092"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2211\/2536","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2211\/2537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2211\/2537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:29:35Z","timestamp":1756376975000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,29]]},"references-count":7,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002211","relation":{"has-manifestation":[{"id-type":"other","id":"1-66-2211-g2536","asserted-by":"subject"},{"id-type":"other","id":"1-66-2211-g2537","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-66","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2021,1,29]]},"article-number":"7"}}