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After three cycles of rituximab (1000 mg on day 0 and 1000 mg on day 15, every 6 months), neurological clinical examination, MRI and electroencephalogram findings were significantly improved.<\/jats:p>","DOI":"10.12890\/2021_002358","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T10:11:37Z","timestamp":1621937497000},"source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of Rituximab on Rheumatoid Leptomeningitis as the First Symptom of Rheumatoid Arthritis"],"prefix":"10.12890","volume":"8","author":[{"given":"Micka\u00ebl","family":"Chouk","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Halb","sequence":"additional","affiliation":[{"name":"Service de Neurologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Mekhail","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Am\u00e9lie","family":"Godot","sequence":"additional","affiliation":[{"name":"Service de M\u00e9decine Interne, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Verhoeven","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cl\u00e9ment","family":"Prati","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Wendling","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHRU Besan\u00e7on, Besan\u00e7on, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2021,4,21]]},"reference":[{"key":"10.12890\/2021_002358_ref1","doi-asserted-by":"crossref","unstructured":"<li>Joaquim AF, Appenzeller S. 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Rheumatoid meningitis: a case report and review of the literature.<em> Neurol Clin Pract<\/em> 2020;<strong>10<\/strong>(1):73\u201383. <\/li>","DOI":"10.1212\/CPJ.0000000000000678"},{"key":"10.12890\/2021_002358_ref4","doi-asserted-by":"crossref","unstructured":"<li>Atzeni F, Talotta R, Masala IF, Gerardi MC, Casale R, Sarzi-Puttini P. Central nervous system involvement in rheumatoid arthritis patients and the potential implications of using biological agents. <em>Best Pract Res Clin Rheumatol<\/em> 2018;<strong>32<\/strong>(4):500\u2013510. <\/li>","DOI":"10.1016\/j.berh.2019.02.003"},{"key":"10.12890\/2021_002358_ref5","doi-asserted-by":"crossref","unstructured":"<li>Turesson C, Schaid DJ, Weyand CM, Jacobsson LTH, Goronzy JJ, Petersson IF, et al. The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. <em>Arthritis Res Ther<\/em> 2005;<strong>7<\/strong>(6):R1386\u2013R1393. <\/li>","DOI":"10.1186\/ar1837"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2358\/2652","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2358\/2653","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2358\/2653","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:26:45Z","timestamp":1756369605000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2358"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,21]]},"references-count":5,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002358","relation":{"has-manifestation":[{"id-type":"other","id":"1-70-2358-g2652","asserted-by":"subject"},{"id-type":"other","id":"1-70-2358-g2653","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-70","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2021,4,21]]},"article-number":"9"}}