{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:41:41Z","timestamp":1771339301443,"version":"3.50.1"},"reference-count":7,"publisher":"SMC Media","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Pulmonary coccidioidomycosis and pulmonary actinomycosis are unheard of as co-pathogens. Infection with these organisms on their own can mimic lung cancer, thus presenting a diagnostic challenge. We present the case of a 75-year-old woman presenting with haemoptysis with a chest CT chest finding of a lung mass suggestive of lung cancer. A diagnosis of concomitant infection by Coccidioides posadasii\/immitis and Actinomyces odontolyticus was made based on culture and histopathology results. The patient was successfully treated with a combination of antifungal and antibacterial therapy. This is the first reported case of co-infection by these two microorganisms.<\/jats:p>","DOI":"10.12890\/2021_002664","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T03:55:35Z","timestamp":1625111735000},"source":"Crossref","is-referenced-by-count":3,"title":["More than Valley Fever: Pulmonary Actinomycosis and Coccidioidomycosis Co-infection in a Patient"],"prefix":"10.12890","volume":"8","author":[{"given":"Abuzar","family":"Asif","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Illinois College of Medicine at Peoria, OSF Saint Francis Medical Center, Peoria, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moni","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Illinois College of Medicine at Peoria, OSF Saint Francis Medical Center, Peoria, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharjeel","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Section of Infectious Diseases, University of Illinois College of Medicine at Peoria, OSF Saint Francis Medical Center, Peoria, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"key":"10.12890\/2021_002664_ref1","doi-asserted-by":"crossref","unstructured":"<li>Galgiani JN, Ampel NM, Catanzaro A, Johnson RH, Stevens DA, Williams PL. Practice guidelines for the treatment of coccidioidomycosis. <em>Clin Infect Dis<\/em> 2000;<strong>30<\/strong>(4):658\u2013661.<\/li>","DOI":"10.1086\/313747"},{"key":"10.12890\/2021_002664_ref2","unstructured":"<li>Farrokh D, Rezaitalab F, Bakhshoudeh B. Pulmonary actinomycosis with endobronchial involvement: a case report and literature review. <em>Tanaffos<\/em> 2014;<strong>13<\/strong>(1):52.<\/li>"},{"key":"10.12890\/2021_002664_ref3","doi-asserted-by":"crossref","unstructured":"<li>Schweigert M, Dubecz A, Beron M, Ofner D, Stein HJ. Pulmonary infections imitating lung cancer: clinical presentation and therapeutical approach. <em>Irish J Med Sci<\/em> 2013;<strong>182<\/strong>(1):73\u201380.<\/li>","DOI":"10.1007\/s11845-012-0831-8"},{"key":"10.12890\/2021_002664_ref4","doi-asserted-by":"crossref","unstructured":"<li>Mayer AP, Morris MF, Panse PM, Ko MG, Files JA, Ruddy BE, et al. Does the presence of mediastinal adenopathy confer a risk for disseminated infection in immunocompetent persons with pulmonary coccidioidomycosis? <em>Mycoses<\/em> 2013;<strong>56<\/strong>(2):145\u2013149.<\/li>","DOI":"10.1111\/j.1439-0507.2012.02224.x"},{"key":"10.12890\/2021_002664_ref5","doi-asserted-by":"crossref","unstructured":"<li>Balis E, Kakavas S, Kompogiorgas S, Kotsifas K, Boulbasakos G. Presentation of pulmonary tuberculosis and actinomyces co-infection as a lung mass: a literature review and unique case report. <em>Monaldi Arch Chest Dis<\/em> 2019;<strong>89<\/strong>(3).<\/li>","DOI":"10.4081\/monaldi.2019.1180"},{"key":"10.12890\/2021_002664_ref6","doi-asserted-by":"crossref","unstructured":"<li>Tanaka S, Araki H, Yoshizako T, Kitagaki H, Isobe T. Pulmonary actinomycosis mimicking pulmonary cancer on fluorine-18 fluorodeoxyglucose PET-CT. <em>Cureus<\/em> 2020;<strong>12<\/strong>(12).<\/li>","DOI":"10.7759\/cureus.12306"},{"key":"10.12890\/2021_002664_ref7","doi-asserted-by":"crossref","unstructured":"<li>Nagaoka K, Izumikawa K, Yamamoto Y, Yanagihara K, Ohkusu K, Kohno S. Multiple lung abscesses caused by Actinomyces graevenitzii mimicking acute pulmonary coccidioidomycosis. <em>J Clin Microbiol<\/em> 2012;<strong>50<\/strong>(9):3125\u20133128.<\/li>","DOI":"10.1128\/JCM.00761-12"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2664\/2745","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2664\/2746","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2664\/2746","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T13:40:02Z","timestamp":1756129202000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2664"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":7,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002664","relation":{"has-manifestation":[{"id-type":"other","id":"1-73-2664-g2745","asserted-by":"subject"},{"id-type":"other","id":"1-73-2664-g2746","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-73","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,1]]},"article-number":"24"}}