{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T12:40:02Z","timestamp":1755866402415,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"Infection with Mycobacterium marinum is common in fish, and so human infection usually arises from contact with contaminated water or fish. A solitary papulonodular lesion on a finger or hand is the typical presentation. Disseminated infections are rare and mostly seen in immunocompromised patients. We present a rare case of disseminated M. marinum infection presenting with polyarthritis, tenosynovitis, dactylitis, and (sub)cutaneous and intramuscular lesions in an immunocompetent patient. This case was complicated by hypercalcemia, renal failure and eventually death. A contaminated rain barrel was most likely the primary source of the infection.<\/jats:p>","DOI":"10.12890\/2021_002864","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T03:50:41Z","timestamp":1637207441000},"source":"Crossref","is-referenced-by-count":2,"title":["A Case of Hypercalcemia in an Immunocompetent Patient with Disseminated Mycobacterium marinum Infection with a Rain Barrel as the Most Likely Primary Source"],"prefix":"10.12890","volume":"8","author":[{"given":"Wendy","family":"Uijtendaal","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rima","family":"Yohanna","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Ziekenhuisgroep Twente, Almelo, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Folkert","family":"Visser","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Ziekenhuisgroep Twente, Almelo, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Ossenkoppele","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ziekenhuisgroep Twente, Almelo, The Netherland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorine","family":"Hess","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Ziekenhuisgroep Twente, Almelo, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis","family":"Boumans","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Ziekenhuisgroep Twente, Almelo, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"10.12890\/2021_002864_ref1","doi-asserted-by":"crossref","unstructured":"
  • Aubry A, Mougari F, Reibel F, Cambau E. Mycobacterium marinum. Microbiol Spectr<\/em> 2017;5<\/strong>(2). <\/li>","DOI":"10.1128\/microbiolspec.TNMI7-0038-2016"},{"key":"10.12890\/2021_002864_ref2","doi-asserted-by":"crossref","unstructured":"
  • Johnson MG, Stout JE. Twenty-eight cases of Mycobacterium marinum infection: retrospective case series and literature review. Infection<\/em> 2015;43<\/strong>(6):655\u2013662. <\/li>","DOI":"10.1007\/s15010-015-0776-8"},{"key":"10.12890\/2021_002864_ref3","doi-asserted-by":"crossref","unstructured":"
  • Holden IK, Kehrer M, Andersen AB, Wejse C, Svensson E, Johansen IS. Mycobacterium marinum infections in Denmark from 2004 to 2017: a retrospective study of incidence, patient characteristics, treatment regimens and outcome. Sci Rep<\/em> 2018;8<\/strong>(1). <\/li>","DOI":"10.1038\/s41598-018-24702-7"},{"key":"10.12890\/2021_002864_ref4","doi-asserted-by":"crossref","unstructured":"
  • Nielsen CT, Andersen \u00c5B. Hypercalcemia and renal failure in a case of disseminated Mycobacterium marinum infection. Eur J Intern Med <\/em>2009;20<\/strong>(2):e29\u201331. <\/li>","DOI":"10.1016\/j.ejim.2008.08.015"},{"key":"10.12890\/2021_002864_ref5","doi-asserted-by":"crossref","unstructured":"
  • Abdulfattah O, Rahman EU, Shweta F, Datar P, Alnafoosi Z, Trauber D, et al. Severe hypercalcemia in a patient with extrapulmonary Mycobacterium abscessus: granuloma or immune reconstitution inflammatory syndrome? First case of Mycobacterium abscessus presenting as retroperitoneal lymphadenopathy with severe hypercalcemia: a case report and literature review. J Community Hosp Intern Med Perspect<\/em> 2018;8<\/strong>(6):331\u2013338. <\/li>","DOI":"10.1080\/20009666.2018.1539057"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2864\/2894","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2864\/2895","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2864\/2895","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T12:18:31Z","timestamp":1755865111000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,18]]},"references-count":5,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002864","relation":{"has-manifestation":[{"id-type":"other","id":"1-79-2864-g2894","asserted-by":"subject"},{"id-type":"other","id":"1-79-2864-g2895","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-79","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2021,11,18]]},"article-number":"12"}}