{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T09:59:36Z","timestamp":1790935176864,"version":"4.1.0"},"reference-count":8,"publisher":"SMC Media","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Spontaneous renal haemorrhage is a rare but severe condition known as Wunderlich syndrome (WS). The classic presentation includes sudden-onset flank pain, a palpable flank mass and hypovolaemic shock (Lenk\u2019s triad). WS can be due to neoplasms, vascular diseases, cystic rupture, coagulopathies and infections. A contrast-enhanced CT scan of the abdomen is mandatory for diagnosis. Surgery is reserved for haemodynamically unstable patients and those with neoplastic disease. We describe a case of WS in an anticoagulated patient with chronic atrial fibrillation, diabetes mellitus type 2 and hypertension, who developed acute renal failure and severe anaemia, that completely resolved with conservative treatment and discontinuation of anticoagulation therapy.<\/jats:p>","DOI":"10.12890\/2022_003269","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T03:31:28Z","timestamp":1649043088000},"source":"Crossref","is-referenced-by-count":11,"title":["A Case of Spontaneous Renal Haemorrhage (Wunderlich Syndrome) in an Anticoagulated Patient"],"prefix":"10.12890","volume":"9","author":[{"given":"Manuela","family":"Giovini","sequence":"additional","affiliation":[{"name":"Intermediate Care Unit, Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Poggiali","sequence":"additional","affiliation":[{"name":"Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piervito","family":"Zocchi","sequence":"additional","affiliation":[{"name":"Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esterina","family":"Bianchi","sequence":"additional","affiliation":[{"name":"Radiology Unit, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elio","family":"Antonucci","sequence":"additional","affiliation":[{"name":"Intermediate Care Unit, Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Barbera","sequence":"additional","affiliation":[{"name":"Intermediate Care Unit, Emergency Department, Guglielmo da Saliceto Hospital, Piacenza, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10397","published-online":{"date-parts":[[2022,4,1]]},"reference":[{"key":"10.12890\/2022_003269_ref1","doi-asserted-by":"crossref","unstructured":"<li>Katabathina VS, Katre R, Prasad SR, Surabhi VR, Shanbhogue AK, Sunnapwar A. Wunderlich syndrome: cross-sectional imaging review. <em>J Comput Assist Tomogr<\/em> 2011;<strong>35<\/strong>(4):425\u2013433. <\/li>","DOI":"10.1097\/RCT.0b013e3182203c5e"},{"key":"10.12890\/2022_003269_ref2","doi-asserted-by":"crossref","unstructured":"<li>Mabjeesh NJ, Matzkin H. Spontaneous subcapsular renal hematoma secondary to anticoagulant therapy. <em>J Urol<\/em> 2001;<strong>165<\/strong>(4):1201. <\/li>","DOI":"10.1016\/S0022-5347(05)66472-5"},{"key":"10.12890\/2022_003269_ref3","doi-asserted-by":"crossref","unstructured":"<li>Ferrando F, Bud\u00eda A, Mira Y, Vay\u00e1 A, Aznar J. Spontaneous renal subcapsular hematoma in an anticoagulated patient. <em>Clin Appl Thromb Hemost<\/em> 2006;<strong>12<\/strong>(1):89\u201392. <\/li>","DOI":"10.1177\/107602960601200114"},{"key":"10.12890\/2022_003269_ref4","doi-asserted-by":"crossref","unstructured":"<li>Zhang JQ, Fielding JR, Zou KH. Etiology of spontaneous perirenal hemorrhage: a meta-analysis. <em>J Urol<\/em> 2002;<strong>167<\/strong>(4):1593\u20131596. <\/li>","DOI":"10.1016\/S0022-5347(05)65160-9"},{"key":"10.12890\/2022_003269_ref5","doi-asserted-by":"crossref","unstructured":"<li>Albi G, del Campo L, Tagarro D. W\u00fcnderlich's syndrome: causes, diagnosis and radiological management. <em>Clin Radiol<\/em> 2002;<strong>57<\/strong>(9):840\u2013845. <\/li>","DOI":"10.1053\/crad.2002.0981"},{"key":"10.12890\/2022_003269_ref6","unstructured":"<li>Parmar N, Langdon J, Kaliannan K, Mathur M, Guo Y, Mahalingam S. Wunderlich syndrome: wonder what it is. <em>Curr Probl Diagn Radiol<\/em> 2021;<strong>9<\/strong>:S0363-0188(21)00016-5. <\/li>"},{"key":"10.12890\/2022_003269_ref7","doi-asserted-by":"crossref","unstructured":"<li>Ahn T, Roberts MJ, Navaratnam A, Chung E, Wood S. Changing etiology and management patterns for spontaneous renal hemorrhage: a systematic review of contemporary series. <em>Int Urol Nephrol<\/em> 2017;<strong>49<\/strong>(11):1897\u20131905. <\/li>","DOI":"10.1007\/s11255-017-1694-8"},{"key":"10.12890\/2022_003269_ref8","doi-asserted-by":"crossref","unstructured":"<li>Chan YC, Morales JP, Reidy JF, Taylor PR. Management of spontaneous and iatrogenic retroperitoneal haemorrhage: conservative management, endovascular intervention or open surgery? <em>Int J Clin Pract<\/em> 2008;<strong>62<\/strong>(10):1604\u20131613. <\/li>","DOI":"10.1111\/j.1742-1241.2007.01494.x"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3269\/3080","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3269\/3081","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3269\/3081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T10:50:13Z","timestamp":1755859813000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,1]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.12890\/2022_003269","relation":{"has-manifestation":[{"id-type":"other","id":"1-84-3269-g3080","asserted-by":"subject"},{"id-type":"other","id":"1-84-3269-g3081","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-84","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,1]]},"article-number":"13"}}