{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T11:10:11Z","timestamp":1755861011130,"version":"3.44.0"},"reference-count":8,"publisher":"SMC Media","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Protein-losing enteropathy (PLGE) is an uncommon condition with a multifactorial origin, that is characterized by excessive loss of serum proteins into the gastrointestinal tract, resulting in hypoproteinaemia and oedema.\u00a0 The authors present the case of a 24-year-old man admitted to hospital for a 2-month history of lower extremity oedema and diarrhoea with a secretory pattern. Blood analysis revealed hypoalbuminaemia and iron deficiency anaemia. Liver disease and severe proteinuria were excluded as possible aetiologies. Upper gastrointestinal endoscopy revealed signs of chronic Helicobacter pylori gastritis. After completion of H. pylori eradication, the patient had complete resolution of clinical and laboratory abnormalities. The results suggest the need to consider less frequent aetiologies for peripheral oedema and hypoproteinaemia, such as PLGE, especially those caused by prevalent bacterial agents like H. pylori.\u00a0<\/jats:p>","DOI":"10.12890\/2022_003312","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T04:08:51Z","timestamp":1653538131000},"source":"Crossref","is-referenced-by-count":0,"title":["Protein-Losing Enteropathy Resolved by Helicobacter pylori Eradication"],"prefix":"10.12890","volume":"9","author":[{"given":"Bruno","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Alves","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catarina","family":"Pestana Santos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiago","family":"Judas Matos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Garcia de Orta, Almada, Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2022,5,26]]},"reference":[{"key":"10.12890\/2022_003312_ref1","doi-asserted-by":"crossref","unstructured":"<li>Elli L, Topa M, Riomondi A. 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Helicobacter pylori isolated from a patient with M\u00e9n\u00e9trier's disease increases hepatocyte growth factor mRNA expression in gastric fibroblasts: comparison with Helicobacter pylori isolated from other gastric diseases. <em>Dig Dis Sci<\/em> 2008 Jul;<strong>53<\/strong>(7):1785\u20131791.<\/li>","DOI":"10.1007\/s10620-007-0070-4"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3312\/3132","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3312\/3133","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3312\/3133","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T10:34:01Z","timestamp":1755858841000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,26]]},"references-count":8,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.12890\/2022_003312","relation":{"has-manifestation":[{"id-type":"other","id":"1-85-3312-g3132","asserted-by":"subject"},{"id-type":"other","id":"1-85-3312-g3133","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-85","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2022,5,26]]},"article-number":"3"}}