{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T02:10:55Z","timestamp":1755828655424,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Uveo-meningeal syndromes are any disorder characterized by the involvement of the uvea and the meninges. They can have multiple causes, including infectious, autoimmune and malignant diseases. We report the case of a patient with a 10-year-old diagnosis of myelodysplastic syndrome that had been stable. He presented with new onset uveitis, ataxia, diplopia and fluctuating consciousness level, without any obvious cause revealed by brain imaging or blood chemistries. An extensive aetiological search showed no obvious cause. Initially, the patient improved spontaneously and was discharged. However, 2 months later, he deteriorated once again, this time with disperse adenomegalies that were not present previously. The bone marrow biopsy showed a high number of blasts, which affirmed the progression of the previously known myelodysplastic syndrome. The lymph nodes were not biopsied due to very low life expectancy, making the procedure futile. A presumptive diagnosis of uveo-meningitis caused by paraneoplastic syndrome was made. The patient died a few months later.<\/jats:p>","DOI":"10.12890\/2022_003633","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T05:06:53Z","timestamp":1667192813000},"source":"Crossref","is-referenced-by-count":0,"title":["Uveo-Meningitis and Myelodysplastic Syndrome"],"prefix":"10.12890","volume":"9","author":[{"given":"Diana","family":"Ferr\u00e3o","sequence":"first","affiliation":[{"name":"Centro Hospitalar e Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Ribeirinho-Soares","sequence":"first","affiliation":[{"name":"Centro Hospitalar e Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Almeida","sequence":"first","affiliation":[{"name":"Centro Hospitalar e Universit\u00e1rio de S\u00e3o Jo\u00e3o, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"key":"10.12890\/2022_003633_ref1","doi-asserted-by":"crossref","unstructured":"<li>Brazis PW, Stewart M, Lee AG. The uveo-meningeal syndromes.<em>Neurologist<\/em> 2004 Jul;<strong>10<\/strong>(4):171\u2013184.<\/li>","DOI":"10.1097\/01.nrl.0000131145.26326.ff"},{"key":"10.12890\/2022_003633_ref2","doi-asserted-by":"crossref","unstructured":"<li>Hadjadj J, Gaube G, Groh M, Paule R, Salah S, Hoogewoud F, et al. The clinical spectrum and outcome of uveomeningitis: a comprehensive analysis of 110 cases. <em>Ocul Immunol Inflamm<\/em> 2021; May <strong>11<\/strong>:1\u20136. <\/li>","DOI":"10.1080\/09273948.2021.1898000"},{"key":"10.12890\/2022_003633_ref3","doi-asserted-by":"crossref","unstructured":"<li>Ray R, Foroozan R. Uveo-meningeal syndromes. <em>Int Ophthalmol Clin<\/em> 2007 Fall;47(4):131\u2013149.<\/li>","DOI":"10.1097\/IIO.0b013e3181572281"},{"key":"10.12890\/2022_003633_ref4","doi-asserted-by":"crossref","unstructured":"<li>Sakata VM, da Silva FT, Hirata CE, de Carvalho JF, Yamamoto JH. Diagnosis and classification of Vogt-Koyanagi-Harada disease. <em>Autoimmun Rev<\/em> 2014 Apr\u2013May;<strong>13<\/strong>(4\u20135):550\u2013555.<\/li>","DOI":"10.1016\/j.autrev.2014.01.023"},{"key":"10.12890\/2022_003633_ref5","doi-asserted-by":"crossref","unstructured":"<li>Abad S, Terrada C, Trad S, S\u00e8ne D, Bielefeld P, Saadoun D, et al. Prise en charge diagnostique des uv\u00e9om\u00e9ningites en m\u00e9decine interne <sup>[Management of uveomeningitis in internal medicine: Proposal for a diagnostic work-up]<\/sup>. <em>Rev Med Interne<\/em> 2016 Jan;<strong>37<\/strong>(1):25\u201334. <\/li>","DOI":"10.1016\/j.revmed.2015.09.009"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3633\/3272","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3633\/3273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3633\/3273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T13:55:28Z","timestamp":1755784528000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,31]]},"references-count":5,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.12890\/2022_003633","relation":{"has-manifestation":[{"id-type":"other","id":"1-91-3633-g3272","asserted-by":"subject"},{"id-type":"other","id":"1-91-3633-g3273","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-91","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2022,10,31]]}}}