{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:49:54Z","timestamp":1756460994619,"version":"3.44.0"},"reference-count":19,"publisher":"SMC Media","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Clostridioides (formerly Clostridium) difficile infection is a common and costly healthcare-associated infection. Extraintestinal C. difficile infection is rarely encountered, especially in isolation. We present a unique case of abdominal wall abscess presenting six months following gastrointestinal (GI) surgery. The patient was managed with computed tomography (CT) guided drainage of the abscess, placement of a drainage catheter, and aggressive broad-spectrum antibiotic treatment for a prolonged duration over multiple admissions.\u00a0<\/jats:p>","DOI":"10.12890\/2023_003711","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T04:45:51Z","timestamp":1672893951000},"source":"Crossref","is-referenced-by-count":3,"title":["Extraintestinal Clostridioides difficile Infection (CDI): A Recurrent Battle with Resilient Abdominal Wall Abscess"],"prefix":"10.12890","volume":"10","author":[{"given":"Justine","family":"Chinnappan","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murtaza Hussain","family":"Murtaza Hussain","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic Awuah","family":"Dominic Awuah","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekwevugbe Ogbon","family":"Ekwevugbe Ogbon","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghassan Bachuwa","family":"Ghassan Bachuwa","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip McDonald","family":"Philip McDonald","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Michigan State University at Hurley Medical Center, Flint, MI, USA; Division of Infectious Disease, Michigan State University at Hurley Medical Center, Flint, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2023,2,3]]},"reference":[{"key":"10.12890\/2023_003711_ref1","doi-asserted-by":"crossref","unstructured":"<li>Leffler DA, Lamont JT. Clostridium difficile infection. <em>N Engl J Med<\/em> 2015;<strong>372<\/strong>:1539-1548.<\/li>","DOI":"10.1056\/NEJMra1403772"},{"key":"10.12890\/2023_003711_ref2","doi-asserted-by":"crossref","unstructured":"<li>Gupta, A., Patel R, Baddour LM, Pardi DS, Khanna S. Extraintestinal Clostridium difficile infections: a single-center experience. <em>Mayo Clin Proc<\/em> 2014;<strong>89<\/strong>:1525-1536.<\/li>","DOI":"10.1016\/j.mayocp.2014.07.012"},{"key":"10.12890\/2023_003711_ref3","doi-asserted-by":"crossref","unstructured":"<li>Jacobs A, Barnard K, Fishel R, Gradon JD. Extracolonic manifestations of Clostridium difficile infections. Presentation of 2 cases and review of the literature. <em>Medicine (Baltimore)<\/em>, 2001;<strong>80<\/strong>:88-101.<\/li>","DOI":"10.1097\/00005792-200103000-00002"},{"key":"10.12890\/2023_003711_ref4","doi-asserted-by":"crossref","unstructured":"<li>Amaya S-L, Rosa E-S, Sergio G-F, Noelia A, Lourdes R-R, Eduardo G, et al. 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Clinical practice guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 focused update guidelines on management of <em>Clostridioides difficile<\/em> infection in adults. <em>Clin Infect Dis<\/em> 2021;<strong>73<\/strong>:e1029-e1044. doi: 10.1093\/cid\/ciab549<\/li>","DOI":"10.1093\/cid\/ciab549"},{"key":"10.12890\/2023_003711_ref7","doi-asserted-by":"crossref","unstructured":"<li>Guh AY, Mu Y, Winston LG, Johnston H, Olson D, Beldavs ZG, Farley MM, et al. Trends in U.S. burden of <em>Clostridioides difficile<\/em> infection and outcomes. <em>N Engl J Med<\/em> 2020;<strong>382<\/strong>:1320-1330.<\/li>","DOI":"10.1056\/NEJMoa1910215"},{"key":"10.12890\/2023_003711_ref8","doi-asserted-by":"crossref","unstructured":"<li>Forrester JD, Maggio PM, Tennakoon L. 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Extra-intestinal infections caused by Clostridium difficile. <em>Clin Microbiol Infect<\/em> 2001;<strong>7<\/strong>:453-457.<\/li>","DOI":"10.1046\/j.1469-0691.2001.00313.x"},{"key":"10.12890\/2023_003711_ref12","doi-asserted-by":"crossref","unstructured":"<li>Wolf LE, Gorbach SL, Granowitz EV. Extraintestinal Clostridium difficile: 10 years\u2019 experience at a tertiary-care hospital. <em>Mayo Clin Proc<\/em> 1998;73:943-947.<\/li>","DOI":"10.4065\/73.10.943"},{"key":"10.12890\/2023_003711_ref13","doi-asserted-by":"crossref","unstructured":"<li>Gardiner BJ, Thorpe CM, Pinkham, NV, McDermott LA, Walk ST, Snydman DR. A repeat offender: recurrent extraintestinal Clostridium difficile infection following fecal microbiota transplantation. <em>Anaerobe<\/em> 2018;51:68-72.<\/li>","DOI":"10.1016\/j.anaerobe.2018.04.007"},{"key":"10.12890\/2023_003711_ref14","doi-asserted-by":"crossref","unstructured":"<li>Herberts M, Hicks B, Sohail MR, Jagtiani A. Secondary bacterial peritonitis and pelvic abscess due to Clostridium difficile. <em>BMJ Case Rep<\/em> 2018;<strong>2018<\/strong>.<\/li>","DOI":"10.1136\/bcr-2018-225252"},{"key":"10.12890\/2023_003711_ref15","doi-asserted-by":"crossref","unstructured":"<li>Mattila E, Arkkila P, Mattila PS, Tarkka E, Tissari P, Anttila V-J. Extraintestinal Clostridium difficile infections. <em>Clin Infect Dis<\/em> 2013;<strong>57<\/strong>:e148-53.<\/li>","DOI":"10.1093\/cid\/cit392"},{"key":"10.12890\/2023_003711_ref16","doi-asserted-by":"crossref","unstructured":"<li>Basnet N, Thapaliya S, Shrotriya S, Kar P, Mitra S. Extraintestinal Clostridium difficile infection: scrotal abscess. <em>Anaerobe<\/em> 2020;<strong>61<\/strong>:102147.<\/li>","DOI":"10.1016\/j.anaerobe.2019.102147"},{"key":"10.12890\/2023_003711_ref17","doi-asserted-by":"crossref","unstructured":"<li>Babar S, Kurdi BE, Iskandarani ME, Haddad I, Imam Z, Alomari M, et al. Oral vancomycin prophylaxis for the prevention of Clostridium difficile infection: a systematic review and meta-analysis. <em>Infect Control Hosp Epidemiol<\/em> 2020;<strong>41<\/strong>:1302-1309.<\/li>","DOI":"10.1017\/ice.2020.277"},{"key":"10.12890\/2023_003711_ref18","doi-asserted-by":"crossref","unstructured":"<li>Tariq R, Laguio-Vila M, Tahir MW, Orenstein R, Pardi DS, Khanna S. et al. Efficacy of oral vancomycin prophylaxis for prevention of <em>Clostridioides difficile<\/em> infection: a systematic review and meta-analysis. <em>Therap Adv Gastroenterol<\/em> 2021;<strong>14<\/strong>:1756284821994046.<\/li>","DOI":"10.1177\/1756284821994046"},{"key":"10.12890\/2023_003711_ref19","doi-asserted-by":"crossref","unstructured":"<li>Zhang K, Beckett P, Abouanaser S, Stankus V, Lee C. Prolonged oral vancomycin for secondary prophylaxis of relapsing Clostridium difficile infection. <em>BMC Infect Dis<\/em> 2019;<strong>19:51.<\/li>","DOI":"10.1186\/s12879-019-3676-1"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3711\/3326","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3711\/3327","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3711\/3327","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T13:22:58Z","timestamp":1755696178000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,3]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.12890\/2023_003711","relation":{"has-manifestation":[{"id-type":"other","id":"1-94-3711-g3326","asserted-by":"subject"},{"id-type":"other","id":"1-94-3711-g3327","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-94","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2023,2,3]]}}}