{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:27:57Z","timestamp":1755800877463,"version":"3.44.0"},"reference-count":3,"publisher":"SMC Media","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction: The Fontan procedure is used to treat congenital heart defects and has improved long-term survival. Long-term complications include liver disease due to congestive hepatopathy. Fontan-related cirrhosis can manifest with ascites, gastrointestinal bleeding and encephalopathy. Case description: A 43-year-old man with history of Fontan surgery was admitted with COVID-19 pneumonia. There was rapid clinical and neurological deterioration, with coma and shock. CT imaging showed thrombosis of the Fontan conduit. The patient was successfully subjected to recanalization of the Fontan circulation, with progressive improvement of coma. Discussion: Fontan-associated liver disease is a major complication following the Fontan procedure. Clinicians must be aware of this pathology during patient follow-up.<\/jats:p>","DOI":"10.12890\/2023_003817","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T08:44:55Z","timestamp":1679906695000},"source":"Crossref","is-referenced-by-count":0,"title":["Hepatic coma secondary to Fontan Conduit thrombosis"],"prefix":"10.12890","volume":"10","author":[{"given":"Jo\u00e3o Lu\u00eds","family":"Cavaco","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Rita","family":"Ferreira","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constan\u00e7a","family":"Abecasis Jalles","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas","family":"Matias Lopes","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"Braz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Oliveira Pedro","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f3nio","family":"Pais de Lacerda","sequence":"first","affiliation":[{"name":"Department of Internal Medicine II, Centro Hospitalar Universit\u00e1rio Lisboa Norte, E.P.E., Lisbon, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2023,4,6]]},"reference":[{"key":"10.12890\/2023_003817_ref1","doi-asserted-by":"crossref","unstructured":"<li>T\u00e9llez L, Rodr\u00edguez-Santiago E, Albillos A. Fontan-associated liver disease: a review. <em>Ann Hepatol<\/em> 2018;<strong>17<\/strong>:192\u2013204. doi: 10.5604\/01.3001.0010.8634. PMID: 29469053.<\/li>","DOI":"10.5604\/01.3001.0010.8634"},{"key":"10.12890\/2023_003817_ref2","doi-asserted-by":"crossref","unstructured":"<li>Emamaullee J, Zaidi AN, Schiano T, Kahn J, Valentino PL, Hofer RE, et al. Fontan-associated liver disease: screening, management, and transplant considerations. <em>Circulation<\/em> 2020;<strong>142<\/strong>:591\u2013604. doi: 10.1161\/CIRCULATIONAHA.120.045597. PMID: 32776846; PMCID: PMC7422927.<\/li>","DOI":"10.1161\/CIRCULATIONAHA.120.045597"},{"key":"10.12890\/2023_003817_ref3","doi-asserted-by":"crossref","unstructured":"<li>Gordon-Walker TT, Bove K, Veldtman G. Fontan-associated liver disease: a review. <em>J Cardiol<\/em> 2019;<strong>74<\/strong>:223\u2013232. doi: 10.1016\/j.jjcc.2019.02.016. PMID: 30928109.<\/li>","DOI":"10.1016\/j.jjcc.2019.02.016"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3817\/3467","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3817\/3468","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3817\/3468","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T12:09:08Z","timestamp":1755691748000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,6]]},"references-count":3,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.12890\/2023_003817","relation":{"has-manifestation":[{"id-type":"other","id":"1-97-3817-g3467","asserted-by":"subject"},{"id-type":"other","id":"1-97-3817-g3468","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-97","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2023,4,6]]}}}