{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:30:17Z","timestamp":1769160617955,"version":"3.49.0"},"reference-count":11,"publisher":"SMC Media","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Adult-onset Still\u2019s disease (AOSD) is a rare autoinflammatory disorder that can lead to a cytokine storm, causing a range of symptoms. Acute intestinal pseudo-obstruction is another rare condition that results in intestinal obstruction without anatomical cause. Although the two conditions are rarely reported together, we present the case of a 62-year-old male who developed acute intestinal pseudo-obstruction in the context of an AOSD flare. This led to severe hypokalaemia and a critical condition. Other symptoms included a high-spiking fever lasting for weeks, polyarthralgias and a typical salmon-coloured rash. After ruling out other potential causes, the patient was diagnosed with AOSD. Our findings suggest that the cytokine storm associated with this disease triggered the acute intestinal pseudo-obstruction and life-threatening hypokalaemia, establishing a causal relationship. Only four other cases of AOSD complicated by intestinal pseudo-obstruction have been reported, and this is the first to present with life-threatening hypokalaemia. This case serves as a crucial reminder that, despite being a diagnosis of exclusion, Still\u2019s disease should be considered as a potential cause of intestinal pseudo-obstruction, as prompt recognition and treatment of the underlying cause is crucial in managing this potentially life-threatening condition.<\/jats:p>","DOI":"10.12890\/2023_003887","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T05:54:20Z","timestamp":1685426060000},"source":"Crossref","is-referenced-by-count":2,"title":["Intestinal pseudo-obstruction with life-threatening hypokalaemia in a patient with adult-onset Still\u2019s disease"],"prefix":"10.12890","volume":"10","author":[{"given":"Pierre","family":"Rossignon","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Moliere-Longchamp Hospital, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Soupart","sequence":"first","affiliation":[{"name":"Research Unit for the Study of Hydromineral Metabolism, Department of Internal Medicine, Erasmus University Hospital, ULB, Brussels, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"10.12890\/2023_003887_ref1","doi-asserted-by":"crossref","unstructured":"<li>Tomaras S, Goetzke CC, Kallinich T, Feist E. Adult-onset Still\u2019s Disease: clinical aspects and therapeutic approach. <em>JCM<\/em> 2021;<strong>10<\/strong>:733.<\/li>","DOI":"10.3390\/jcm10040733"},{"key":"10.12890\/2023_003887_ref2","doi-asserted-by":"crossref","unstructured":"<li>Batke M, Cappell MS. Adynamic ileus and acute colonic pseudo-obstruction. <em>Med Clin North Am<\/em> 2008;<strong>92<\/strong>:649\u201370.<\/li>","DOI":"10.1016\/j.mcna.2008.01.002"},{"key":"10.12890\/2023_003887_ref3","unstructured":"<li>Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, et al. Preliminary criteria for classification of adult Still\u2019s disease. <em>J Rheumatol<\/em> 1992;<strong>19<\/strong>:424\u201330.<\/li>"},{"key":"10.12890\/2023_003887_ref4","doi-asserted-by":"crossref","unstructured":"<li>Gerfaud-Valentin M, Jamilloux Y, Iwaz J, S\u00e8ve P. 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Calcinosis cutis and intestinal pseudoobstruction in a patient with adult onset Still\u2019s disease associated with recurrent relapses of disordered coagulopathy. <em>Intern Med<\/em> 1999;<strong>38<\/strong>:516\u201320.<\/li>","DOI":"10.2169\/internalmedicine.38.516"},{"key":"10.12890\/2023_003887_ref7","doi-asserted-by":"crossref","unstructured":"<li>El Younsi S, Perlemuter G, Clerc D, Buffet C, Pelletier G. Maladie de Still et pseudo-obstruction intestinale [Still\u2019s disease and intestinal pseudo-obstruction]. <em>Gastroenterol Clin Biol<\/em> 2004;<strong>28<\/strong>:309\u201310.<\/li>","DOI":"10.1016\/S0399-8320(04)94925-1"},{"key":"10.12890\/2023_003887_ref8","doi-asserted-by":"crossref","unstructured":"<li>Hori H, Yabe H, Fukuchi T, Sugawara H. 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Adult-onset Still disease. <em>Best Pract Res Clin Rheumatol<\/em> 2008;<strong>22<\/strong>:773\u201392.<\/li>","DOI":"10.1016\/j.berh.2008.08.006"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3887\/3528","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3887\/3529","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3887\/3529","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T10:14:54Z","timestamp":1755684894000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3887"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,30]]},"references-count":11,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.12890\/2023_003887","relation":{"has-manifestation":[{"id-type":"other","id":"1-100-3887-g3528","asserted-by":"subject"},{"id-type":"other","id":"1-100-3887-g3529","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-100","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,30]]}}}