{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:16:00Z","timestamp":1755800160151,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction:\u00a0We present a clinical case of a 45-year-old man with recurrent deep vein thrombosis (DVT) and multiple hospital admissions due to severe infectious conditions. A newfound hypoalbuminemia raised the suspicion of a protein-losing condition, with an upper endoscopy revealing lesions at the D2 level compatible with coeliac sprue and HLA typing positive for both DQ-2 and DQ-8. Methods:\u00a0A gluten free diet was started and apixaban was suspended. Results:\u00a0No new complications were reported. Discussion:\u00a0Multiple mechanisms are believed to be behind the association between DVT and coeliac disease. However, to this date, no consensus exists regarding the ideal duration of anticoagulation.<\/jats:p>","DOI":"10.12890\/2023_003977","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T06:35:46Z","timestamp":1692599746000},"source":"Crossref","is-referenced-by-count":0,"title":["Deep vein thrombosis revealing a \"silent\" coeliac disease"],"prefix":"10.12890","volume":"10","author":[{"given":"Sofia","family":"Miranda","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Hospital do Divino Esp\u00edrito Santo, Ponta Delgada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia","family":"Clara","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Tr\u00e1s-os-Montes e Alto Douro, Vila Real, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Rua","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Tr\u00e1s-os-Montes e Alto Douro, Vila Real, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Cimbron","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Hospital do Divino Esp\u00edrito Santo, Ponta Delgada, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Salvador","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Centro Hospitalar de Tr\u00e1s-os-Montes e Alto Douro, Vila Real, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"key":"10.12890\/2023_003977_ref1","doi-asserted-by":"crossref","unstructured":"<li>Pantic N, Pantic I, Jevtic D, Mogulla V, Oluic S, Durdevic M et al. Celiac disease and thrombotic events: A systematic review of published cases. <em>Nutrients<\/em> 2022;<strong>14<\/strong>:2162.<\/li>","DOI":"10.3390\/nu14102162"},{"key":"10.12890\/2023_003977_ref2","doi-asserted-by":"crossref","unstructured":"<li>Fousekis FS, Beka ET, Mitselos IV, Milionis H, Christodoulou DK. Thromboembolic complications and cardiovascular events associated with celiac disease. <em>Ir J Med Sci<\/em> 2021;<strong>190<\/strong>:133\u2013141.<\/li>","DOI":"10.1007\/s11845-020-02315-2"},{"key":"10.12890\/2023_003977_ref3","doi-asserted-by":"crossref","unstructured":"<li>Dumic I, Martin S, Salfiti N, Watson R, Alempijevic T. Deep vein thrombosis and bilateral pulmonary embolism revealing silent celiac disease: Case report and review of literature. <em>Case Rep Gastrointest Med<\/em> 2017;<strong>2017<\/strong>:5236918.<\/li>","DOI":"10.1155\/2017\/5236918"},{"key":"10.12890\/2023_003977_ref4","doi-asserted-by":"crossref","unstructured":"<li>Alhosain D, Kouba L. Concurrent cerebral arterial and venous sinus thrombosis revealing celiac disease\u2014A case report and literature review. <em>BMC Gastroenterol<\/em> 2020;<strong>20<\/strong>:327.<\/li>","DOI":"10.1186\/s12876-020-01483-w"},{"key":"10.12890\/2023_003977_ref5","doi-asserted-by":"crossref","unstructured":"<li>Grigg AP. Deep venous thrombosis as the presenting feature in a patient with celiac disease and homocysteinemia. <em>Aust N Z J Med<\/em> 1999;<strong>29<\/strong>:566\u20137.<\/li>","DOI":"10.1111\/j.1445-5994.1999.tb00764.x"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3977\/3625","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3977\/3626","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/3977\/3626","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T07:58:59Z","timestamp":1755676739000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/3977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,18]]},"references-count":5,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.12890\/2023_003977","relation":{"has-manifestation":[{"id-type":"other","id":"1-104-3977-g3625","asserted-by":"subject"},{"id-type":"other","id":"1-104-3977-g3626","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-104","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2023,8,18]]}}}