{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T15:14:58Z","timestamp":1767626098179,"version":"3.44.0"},"reference-count":7,"publisher":"SMC Media","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction:\u00a0Guillain-Barr\u00e9 syndrome is an acute, inflammatory polyradiculoneuropathy of autoimmune aetiology. It is a rare disease seen in 1 in 100,000 person-years. Up to 20% of those affected develop severe disability; mortality in Guillain-Barr\u00e9 syndrome is 5%. Guillain-Barr\u00e9, associated with many malignancies as a paraneoplastic phenomenon, has been reported \u2013 especially in haematological malignancies such as lymphoma and leukaemia. Solid tumours associated with paraneoplastic Guillain-Barr\u00e9 syndrome are breast and lung cancers. The association between paraneoplastic Guillain-Barr\u00e9 syndrome and gynaecological malignancies are rare, and only a handful of cases have been previously reported in gynaecological cancers. Case description:\u00a0We discuss a 65-year-old Sri Lankan female patient diagnosed with metastatic endometrial carcinoma who presented with paraneoplastic Guillain-Barr\u00e9 syndrome. The patient was treated appropriately and eventually recovered from her condition. Conclusion:\u00a0Paraneoplastic Guillain-Barr\u00e9 syndrome is a rare phenomenon that clinicians can easily miss, and it has rarely been described in gynaecological cancers. Our patient was diagnosed with this rare phenomenon. The timely recognition and prompt treatment of this potentially life-threatening condition with multiple complications is essential in managing patients with malignancies and neuropathy. Further studies on paraneoplastic Guillain-Barr\u00e9 syndrome are needed as cases may be underreported.<\/jats:p>","DOI":"10.12890\/2023_004077","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T11:11:55Z","timestamp":1700219515000},"source":"Crossref","is-referenced-by-count":1,"title":["A rare case of paraneoplastic Guillain-Barr\u00e9 syndrome in a patient with endometrial cancer"],"prefix":"10.12890","volume":"10","author":[{"given":"Asif Mohamed","family":"Farook","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilshan","family":"Priyankara","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chamali","family":"Aluwihare","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Mendis","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2023,11,17]]},"reference":[{"key":"10.12890\/2023_004077_ref1","doi-asserted-by":"crossref","unstructured":"<li>Svarna A, Liontos M, Reppas G, Fiste O, Andrikopoulou A, Dimopoulos MA, et al. What to expect from paraneoplastic syndromes of the nervous system in uterine cancer: a review of the literature. <em>Gynecol Oncol Rep<\/em> 2023;<strong>45<\/strong>:101136.<\/li>","DOI":"10.1016\/j.gore.2023.101136"},{"key":"10.12890\/2023_004077_ref2","doi-asserted-by":"crossref","unstructured":"<li>Willison HJ. The immunobiology of Guillain-Barr\u00e9 syndromes. <em>J Peripher Nerv Syst<\/em> 2005;<strong>10<\/strong>:94\u2013112.<\/li>","DOI":"10.1111\/j.1085-9489.2005.0010202.x"},{"key":"10.12890\/2023_004077_ref3","doi-asserted-by":"crossref","unstructured":"<li>Vallat JM, De Mascarel HA, Bordessoule D, Jauberteau MO, Tabaraud F, Gelot A, et al. Non-Hodgkin malignant lymphomas and peripheral neuropathies\u201413 cases. <em>Brain<\/em> 1995;<strong>118<\/strong>:1233\u20131245.<\/li>","DOI":"10.1093\/brain\/118.5.1233"},{"key":"10.12890\/2023_004077_ref4","doi-asserted-by":"crossref","unstructured":"<li>Vigliani MC, Magistrello M, Polo P, Mutani R, Chi\u00f2 A. 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Vincristine neuropathy and a Guillain-Barr\u00e9 syndrome: a case with acute lymphatic leukemia and quadriparesis. <em>Eur J Haematol<\/em> 1987;<strong>39<\/strong>:75\u201376.<\/li>","DOI":"10.1111\/j.1600-0609.1987.tb00168.x"},{"key":"10.12890\/2023_004077_ref7","doi-asserted-by":"crossref","unstructured":"<li>Brzezinska BN, Higgins RV, Rungruang B. Guillain-Barr\u00e9 Syndrome in a patient with uterine adenocarcinoma undergoing treatment with immune-checkpoint inhibitor therapy: a case report and review of the literature. <em>Gynecol Oncol Rep<\/em> 2021;<strong>36<\/strong>:100739.<\/li>","DOI":"10.1016\/j.gore.2021.100739"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4077\/3722","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4077\/3723","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4077\/3723","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T07:30:02Z","timestamp":1755675002000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/4077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,17]]},"references-count":7,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.12890\/2023_004077","relation":{"has-manifestation":[{"id-type":"other","id":"1-107-4077-g3722","asserted-by":"subject"},{"id-type":"other","id":"1-107-4077-g3723","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-107","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2023,11,17]]}}}