{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T12:53:25Z","timestamp":1778763205504,"version":"3.51.4"},"reference-count":11,"publisher":"SMC Media","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Peritonitis, the inflammation of the protective membrane surrounding parts of the abdominal organs, is a common clinical pathology with multifactorial aetiologies. While bacterial infections are well-recognised as a cause of peritonitis, fungal infections remain relatively uncommon especially\u00a0Saccharomyces cerevisiae, which is commonly used for breadmaking and as a nutritional supplement. This fungus has been reported to induce peritonitis in patients on peritoneal dialysis. However, it has never been reported as secondary to percutaneous endoscopic gastrostomy (PEG) tube insertion in immunocompromised patients. We present a 64-year-old female with a history of human immunodeficiency virus (HIV) who developed\u00a0S. cerevisiae\u00a0peritonitis following PEG tube insertion. The case highlights the importance of considering rare organisms when treating immunocompromised patients with peritonitis, especially after gastrointestinal tract penetration or peritoneal membrane disruption.<\/jats:p>","DOI":"10.12890\/2024_004354","type":"journal-article","created":{"date-parts":[[2024,3,4]],"date-time":"2024-03-04T06:50:18Z","timestamp":1709535018000},"source":"Crossref","is-referenced-by-count":1,"title":["Baker\u2019s yeast might not always be good for everyone \u2013 a case of percutaneous gastrostomy tube induced Saccharomyces cerevisiae peritonitis in an immunocompromised patient"],"prefix":"10.12890","volume":"11","author":[{"given":"Mohammad","family":"Kloub","sequence":"first","affiliation":[{"name":"Saint Michael's Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Hussain","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Michael\u2019s Medical Center, Newark, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fnu","family":"Marium","sequence":"first","affiliation":[{"name":"Jinnah Sindh Medical University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atheer","family":"Anwar","sequence":"first","affiliation":[{"name":"General Physician"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Haddad","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Saint Michael\u2019s Medical Center, Newark, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihad","family":"Slim","sequence":"first","affiliation":[{"name":"Department of Infectious Disease, Saint Michael\u2019s Medical Center, Newark, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yatinder","family":"Bains","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Michael\u2019s Medical Center, Newark, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2024,3,1]]},"reference":[{"key":"10.12890\/2024_004354_ref1","doi-asserted-by":"crossref","unstructured":"<li>Swann H, Hughes D. Diagnosis and management of peritonitis. <em>Vet Clin North Am Small Anim Pract<\/em> 2000;<strong>30<\/strong>:603\u2013615.<\/li>","DOI":"10.1016\/S0195-5616(00)50041-2"},{"key":"10.12890\/2024_004354_ref2","doi-asserted-by":"crossref","unstructured":"<li>Duina AA, Miller ME, Keeney JB. Budding yeast for budding geneticists: a primer on the Saccharomyces cerevisiae model system. <em>Genetics<\/em> 2014;<strong>197<\/strong>:33\u201348. <\/li>","DOI":"10.1534\/genetics.114.163188"},{"key":"10.12890\/2024_004354_ref3","unstructured":"<li>Bouza E, Munoz P. Saccharomyces cerevisiae: the end of the innocence. <em>Rev Esp Quimioter<\/em> 2004;<strong>17<\/strong>:227-231. <\/li>"},{"key":"10.12890\/2024_004354_ref4","doi-asserted-by":"crossref","unstructured":"<li>Kiehn TE, Edwards FF, Armstrong D. The prevalence of yeasts in clinical specimens from cancer patients. <em>Am J Clin Pathol<\/em> 1980;<strong>73<\/strong>:518-521. <\/li>","DOI":"10.1093\/ajcp\/73.4.518"},{"key":"10.12890\/2024_004354_ref5","doi-asserted-by":"crossref","unstructured":"<li>Wombwell E, Bransteitter B, Gillen LR. Incidence of Saccharomyces cerevisiae fungemia in hospitalised patients administered Saccharomyces boulardii probiotic. <em>Mycoses<\/em> 2021;<strong>64<\/strong>:1521\u20131526. <\/li>","DOI":"10.1111\/myc.13375"},{"key":"10.12890\/2024_004354_ref6","doi-asserted-by":"crossref","unstructured":"<li>Dougherty SH, Simmons RL. Postoperative peritonitis caused by Saccharomyces cerevisiae. <em>Arch Surg<\/em> 1982;<strong>117<\/strong>:248. <\/li>","DOI":"10.1001\/archsurg.1982.01380260114019"},{"key":"10.12890\/2024_004354_ref7","unstructured":"<li>Hamoud S, Keidar Z, Hayek T. Recurrent Saccharomyces cerevisiae fungemia in an otherwise healthy patient. <em>Isr Med Assoc J<\/em> 2011;<strong>13<\/strong>:575\u2013576. <\/li>"},{"key":"10.12890\/2024_004354_ref8","doi-asserted-by":"crossref","unstructured":"<li>Perez-Torrado R, Querol A. Saccharomyces cerevisiae show low levels of traversal across human endothelial barrier <em>in vitro<\/em>. <em>F1000Res<\/em> 2017;<strong>6<\/strong>:944. <\/li>","DOI":"10.12688\/f1000research.11782.2"},{"key":"10.12890\/2024_004354_ref9","doi-asserted-by":"crossref","unstructured":"<li>Yoshida M, Obayashi T, Iwama A, Ito M, Tsunoda S, Suzuki T, et al. Detection of plasma (1-3)-beta-D-glucan in patients with Fusarium, Trichosporon, Saccharomyces and Acremonium fungaemias. <em>J Med Vet Mycol<\/em> 1997;<strong>35<\/strong>:371\u2013374. <\/li>","DOI":"10.1080\/02681219780001441"},{"key":"10.12890\/2024_004354_ref10","doi-asserted-by":"crossref","unstructured":"<li>Popiel KY, Wong P, Lee MJ, Langelier M, Sheppard DC, Vinh DC. Invasive Saccharomyces cerevisiae in a liver transplant patient: case report and review of infection in transplant recipients. <em>Transpl Infect Dis<\/em> 2015;<strong>17<\/strong>:435\u2013441. <\/li>","DOI":"10.1111\/tid.12384"},{"key":"10.12890\/2024_004354_ref11","unstructured":"<li>Gomila Sard B, T\u00e9llez-Castillo CJ, Garc\u00eda P\u00e9rez H, Moreno Munoz R. [Peritonitis caused by Saccharomyces cerevisiae in an ambulatory peritoneal dialysis patient]. <em>Nefrolog\u00eda (English Edition)<\/em> 2009;<strong>29<\/strong>:371\u2013372<\/li>"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4354\/3882","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4354\/3883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/4354\/3883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T10:37:38Z","timestamp":1755599858000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/4354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,1]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.12890\/2024_004354","relation":{"has-manifestation":[{"id-type":"other","id":"1-111-4354-g3882","asserted-by":"subject"},{"id-type":"other","id":"1-111-4354-g3883","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-111","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,1]]}}}