{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:38:50Z","timestamp":1722991130145},"reference-count":0,"publisher":"SMC Media","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Chylothorax is the accumulation of lymphatic fluid (chyle) within the pleural space. There are multiple causes, including traumatic and non-traumatic mechanisms. Trauma can cause disruption of the thoracic duct either by direct damage or indirect crushing or avulsion mechanisms. Non-traumatic causes include infections, inflammatory processes, malignancies, and iatrogenic injury (during surgery or central venous access). The traditional management of traumatic chylothorax has been either a conservative approach, including complete nil per os, or a low-fat diet with medium-chain triglyceride supplementation with the administration of somatostatin or its analog, octreotide, versus a surgical approach consisting of thoracic duct ligation. Recently a less invasive approach via thoracic duct embolization has gained popularity. There have been a few reports of the successful use of an alpha 1-adrenergic agonist (midodrine) as an adjunct in the conservative approach. We describe the utility of midodrine in three cases of chylothorax and propose a management algorithm.<\/jats:p>","DOI":"10.12890\/2024_004705","type":"journal-article","created":{"date-parts":[[2024,7,29]],"date-time":"2024-07-29T15:04:40Z","timestamp":1722265480000},"source":"Crossref","is-referenced-by-count":0,"title":["Utility of an alpha-1 adrenergic agonist in the management of chylothorax: a case series and management algorithm"],"prefix":"10.12890","author":[{"given":"Ruben","family":"Peralta","sequence":"first","affiliation":[{"name":"Department of Surgery, Trauma Surgery, Hamad Medical Corporation (HMC), Doha, Qatar; Department of Surgery, Universidad Nacional Pedro Henriquez Urena, Santo Domingo, Dominican Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed F.","family":"Ramzee","sequence":"first","affiliation":[{"name":"Department of Surgery, Trauma Surgery, Hamad Medical Corporation (HMC), Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeenat Khuda","family":"Bakhsh","sequence":"first","affiliation":[{"name":"Department of Surgery, Trauma Surgery, Hamad Medical Corporation (HMC), Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"El-Menyar","sequence":"first","affiliation":[{"name":"Department of Surgery, Clinical Research, Trauma & Vascular Surgery, HMC, Doha, Qatar; Department of Clinical Medicine, Weill Cornell Medical College, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Ajaj","sequence":"first","affiliation":[{"name":"Department of Surgery, Trauma Surgery, Hamad Medical Corporation (HMC), Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Al-Thani","sequence":"first","affiliation":[{"name":"Department of Surgery, Trauma Surgery, Hamad Medical Corporation (HMC), Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2024,7,29]]},"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T08:23:25Z","timestamp":1722932605000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/4705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,29]]},"references-count":0,"URL":"https:\/\/doi.org\/10.12890\/2024_004705","relation":{"has-manifestation":[{"id-type":"other","id":"1-116-4705-g4179","asserted-by":"subject"},{"id-type":"other","id":"1-116-4705-g4180","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-116","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2024,7,29]]}}}