{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:56:31Z","timestamp":1761598591483,"version":"3.44.0"},"reference-count":6,"publisher":"SMC Media","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Autoimmune\/inflammatory syndrome is a complex condition characterized by various autoimmune and inflammatory symptoms following the exposure to an adjuvant such as silicone. Autoimmune\/inflammatory syndrome induced by adjuvants (ASIA) is challenging to diagnose because it can mimic other autoimmune diseases and requires specific criteria for identification. We report a case of a 35-year-old woman who developed inflammatory joint pain, fatigue and myalgia after receiving silicone breast implants. Symptoms improved significantly after administration of steroids. Based on the fulfilment of the ASIA diagnostic criteria, the diagnosis was made. This case emphasizes the importance of understanding this condition in patients with unexplained systemic symptoms after exposure to adjuvants.<\/jats:p>","DOI":"10.12890\/2025_005048","type":"journal-article","created":{"date-parts":[[2025,2,4]],"date-time":"2025-02-04T08:35:17Z","timestamp":1738658117000},"source":"Crossref","is-referenced-by-count":3,"title":["Autoimmune\/inflammatory syndrome induced by adjuvants (ASIA) after silicone breast implants"],"prefix":"10.12890","volume":"12","author":[{"given":"Jaouad","family":"Yousfi","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Mohammed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soukaina","family":"Oumlil","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Mohammed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lamiaa","family":"Essaadouni","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, University Hospital of Mohammed VI, Marrakesh, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"doi-asserted-by":"crossref","unstructured":"<li>Shoenfeld Y, Agmon-Levin N. \u2018ASIA\u2019 - autoimmune\/inflammatory syndrome induced by adjuvants. <em>J Autoimmun<\/em> 2011;<strong>36<\/strong>:4-8.<\/li>","key":"10.12890\/2025_005048_ref1","DOI":"10.1016\/j.jaut.2010.07.003"},{"doi-asserted-by":"crossref","unstructured":"<li>Watad A, Quaresma M, Brown S, Cohen Tervaert JW, Rodr\u00edguez-Pint I, Cervera R, et al. Autoimmune\/inflammatory syndrome induced by adjuvants (Shoenfeld\u2019s syndrome) - An update. <em>Lupus<\/em> 2017;<strong>26<\/strong>:675-681.<\/li>","key":"10.12890\/2025_005048_ref2","DOI":"10.1177\/0961203316686406"},{"doi-asserted-by":"crossref","unstructured":"<li>Watad A, Sharif K, Shoenfeld Y. The ASIA syndrome: basic concepts. <em>MJR<\/em> 2017;<strong>28<\/strong>:64\u201369.<\/li>","key":"10.12890\/2025_005048_ref3","DOI":"10.31138\/mjr.28.2.64"},{"doi-asserted-by":"crossref","unstructured":"<li>Nunes E Silva D, Gr\u00fcndler C, Spengler MDGMT, Horimoto AMC, Machado MA, Fraz\u00e3o IC et al. Autoimmune Syndrome Induced by Adjuvants (ASIA) after Silicone Breast Augmentation Surgery. <em>Plast Reconstr Surg Glob Open<\/em> 2017;<strong>5<\/strong>:e1487.<\/li>","key":"10.12890\/2025_005048_ref4","DOI":"10.1097\/GOX.0000000000001487"},{"doi-asserted-by":"crossref","unstructured":"<li>Hoa S, Milord K, Hudson M, Nicolaidis SC, Bourr\u00e9-Tessier J. Risk of rheumatic disease in breast implant users: a qualitative systematic review. <em>Gland Surg<\/em> 2021;<strong>10<\/strong>:2557-2576.<\/li>","key":"10.12890\/2025_005048_ref5","DOI":"10.21037\/gs-21-266"},{"doi-asserted-by":"crossref","unstructured":"<li>Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, et al. A method for estimating the probability of adverse drug reactions. <em>Clin Pharmacol Ther<\/em> 1981;<strong>30<\/strong>:239-245.<\/li>","key":"10.12890\/2025_005048_ref6","DOI":"10.1038\/clpt.1981.154"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/5048\/4430","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/5048\/4432","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/5048\/4432","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T09:42:36Z","timestamp":1755596556000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/5048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,7]]},"references-count":6,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.12890\/2025_005048","relation":{"has-manifestation":[{"id-type":"other","id":"1-122-5048-g4430","asserted-by":"subject"},{"id-type":"other","id":"1-122-5048-g4432","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-122","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2025,1,7]]}}}