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This case highlights the limitations of current diagnostic modalities and emphasises the urgent need for further research into improved early detection methods, molecular characterisation and effective treatment strategies for this rare and lethal subtype of pancreatic cancer.<\/jats:p>","DOI":"10.12890\/2025_005662","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T15:34:10Z","timestamp":1755876850000},"source":"Crossref","is-referenced-by-count":0,"title":["Rapid metastatic growth of a pancreatic signet ring cell carcinoma within 6 weeks of a negative CT"],"prefix":"10.12890","volume":"12","author":[{"given":"Toni","family":"Habib","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micaela","family":"Prisco","sequence":"first","affiliation":[{"name":"CUNY School of Medicine, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Mounas","sequence":"first","affiliation":[{"name":"Rowan-Virtua School of Osteopathic Medicine, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chloe","family":"Lahoud","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saif","family":"Yasin","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Sohail","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan Al Moussawi","family":"Hassan Al Moussawi","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, Staten Island University Hospital, Northwell Health, Staten Island, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2025,8,22]]},"reference":[{"key":"10.12890\/2025_005662_ref1","doi-asserted-by":"crossref","unstructured":"Siegel RL, Miller KD, Jemal A. 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