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Conclusion:\u00a0This case supports JAK inhibitors as a promising therapeutic strategy in refractory DCS, highlighting their potential role in managing challenging inflammatory dermatoses.<\/jats:p>","DOI":"10.12890\/2025_005743","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T14:39:23Z","timestamp":1756478363000},"source":"Crossref","is-referenced-by-count":4,"title":["Janus kinase inhibitors as a breakthrough treatment for refractory dissecting cellulitis of the scalp"],"prefix":"10.12890","volume":"12","author":[{"given":"Ali","family":"Al-Mamoori","sequence":"first","affiliation":[{"name":"Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajjad Ghanim Awad","family":"Al-Badri","sequence":"first","affiliation":[{"name":"College of Medicine, University of Warith Al-Anbiyaa, Karbala, Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabry Babiker H.","family":"Sayed","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health Sciences, International University of Africa, Khartoum, Sudan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael","family":"Al-Daraji","sequence":"first","affiliation":[{"name":"Dermatology Department, Ain Shams University Hospital, Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10397","published-online":{"date-parts":[[2025,8,29]]},"reference":[{"key":"10.12890\/2025_005743_ref1","doi-asserted-by":"crossref","unstructured":"Scheinfeld N. Dissecting cellulitis (Perifolliculitis Capitis Abscedens et Suffodiens): a comprehensive review focusing on new treatments and findings of the last decade with commentary comparing the therapies and causes of dissecting cellulitis to hidradenitis suppurativa. Dermatol Online J 2014;20:22692.","DOI":"10.5070\/D3205022692"},{"key":"10.12890\/2025_005743_ref2","doi-asserted-by":"crossref","unstructured":"Vasanth V, Chandrashekar BS. Follicular occlusion tetrad. Indian Dermatol Online J 2014;5:491-493. doi: 10.4103\/2229-5178.142517","DOI":"10.4103\/2229-5178.142517"},{"key":"10.12890\/2025_005743_ref3","doi-asserted-by":"crossref","unstructured":"Masson R, Jeong CY, Ma E, Crew AB, Fragoso NM, Shi VY, et al. Treatments for Dissecting Cellulitis of the Scalp: A Systematic Review and Treatment Algorithm. Dermatol Ther (Heidelb) 2023;13:2487-2526. doi: 10.1007\/s13555-023-01018-7","DOI":"10.1007\/s13555-023-01018-7"},{"key":"10.12890\/2025_005743_ref4","doi-asserted-by":"crossref","unstructured":"Zouboulis CC, Frew JW, Giamarellos-Bourboulis EJ, Jemec GBE, Del Marmol V, Marzano AV, et al. Target molecules for future hidradenitis suppurativa treatment. Exp Dermatol 2021;30:8-17. doi: 10.1111\/exd.14338","DOI":"10.1111\/exd.14338"},{"key":"10.12890\/2025_005743_ref5","doi-asserted-by":"crossref","unstructured":"Howell MD, Kuo FI, Smith PA. Targeting the Janus Kinase Family in Autoimmune Skin Diseases. Front Immunol 2019;10:2342. doi: 10.3389\/fimmu.2019.02342","DOI":"10.3389\/fimmu.2019.02342"},{"key":"10.12890\/2025_005743_ref6","doi-asserted-by":"crossref","unstructured":"Mansilla-Polo M, Escutia-Mu\u00f1oz B, Botella-Estrada R. Narrative Review and Update on Biologic and Small Molecule Drugs for Hidradenitis Suppurativa: An Entity With a Promising Future. Actas Dermosifiliogr 2023;114:772-783. doi: 10.1016\/j.ad.2023.05.015","DOI":"10.1016\/j.ad.2023.05.015"},{"key":"10.12890\/2025_005743_ref7","doi-asserted-by":"crossref","unstructured":"Sadeghzadeh Bazargan A, Pashaei A, Goodarzi A. Successful treatment of Hidradenitis Suppurativa with tofacitinib: two cases and a review of the literature. Oxf Med Case Reports 2023;2023:omad003. doi: 10.1093\/omcr\/omad003","DOI":"10.1093\/omcr\/omad003"},{"key":"10.12890\/2025_005743_ref8","doi-asserted-by":"crossref","unstructured":"Islam Z, Toker M, Gandhi IM, Sher A, Campton K. Improvement of Recalcitrant Dissecting Cellulitis of the Scalp After a Trial of Upadacitinib. Cureus 2024;16:e52377. doi: 10.7759\/cureus.52377","DOI":"10.7759\/cureus.52377"},{"key":"10.12890\/2025_005743_ref9","doi-asserted-by":"crossref","unstructured":"Mohan S, Singh N, Mohan L. Tofacitinib as a potential therapeutic agent: a review. Int J Res Dermatol 2024;10:215\u2013219. doi:10.18203\/issn.2455-4529.IntJResDermatol2024159","DOI":"10.18203\/issn.2455-4529.IntJResDermatol20241595"},{"key":"10.12890\/2025_005743_ref10","doi-asserted-by":"crossref","unstructured":"Qiu M, Man X, Jing J. Dissecting Cellulitis of the Scalp Successfully Treated with a Combination of Ixekizumab and Tofacitinib. 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