{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T18:31:08Z","timestamp":1767983468556,"version":"3.49.0"},"reference-count":10,"publisher":"SMC Media","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Introduction:\u00a0Foix-Chavany-Marie syndrome (FCMS) or bilateral opercular syndrome (OPS) is a rare pseudobulbar palsy characterized by facial, lingual, pharyngeal, and masticatory voluntary muscle paralysis resulting in anarthria with preservation of autonomic, involuntary, and reflexive functions. Damage to the posterior part of the inferior frontal gyrus and inferior part of precentral gyrus play a role in the pathogenesis of FCMS. Case description:\u00a0We report a rare case of bilateral OPS following an acute right middle cerebral artery (MCA) infarct in a patient with history of glioblastoma, and resection in the left MCA territory within the cingulate gyrus, showing recovery of speech and swallowing despite intensive bilateral opercular lesions owing to extensive multidisciplinary team support. However, the patient was discharged with a percutaneous endoscopic gastrostomy tube for long-term enteral feeding support due to partial recovery. Discussion:\u00a0The patient\u2019s history of glioblastoma, left MCA cingulate gyrus resection and right MCA infarction with automatic-voluntary dissociation led to the diagnosis of FCMS. Rehabilitation surprisingly showed mild improvement in speech and swallowing despite extensive bilateral opercular lesions proving that there are still chances of improvement in speech and swallowing in OPS with the right multidisciplinary approach. Conclusion:\u00a0Patients with a history of brain tumours like glioblastoma can develop bilateral OPS later in life in case of other vascular events that cause lesions in a previously unaffected operculum, triggering symptoms. Extensive involvement of the speech and language team is of significant in the management of FCMS cases as above where some recovery might still be seen.<\/jats:p>","DOI":"10.12890\/2025_006016","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T10:39:32Z","timestamp":1766399972000},"source":"Crossref","is-referenced-by-count":0,"title":["A case of Foix-Chavany-Marie syndrome with history of glioblastoma showing partial recovery"],"prefix":"10.12890","volume":"13","author":[{"given":"Deeksha","family":"Seth","sequence":"first","affiliation":[{"name":"Stroke Department, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Musab","family":"Eltahir","sequence":"first","affiliation":[{"name":"Neurology Department, Southmead Hospital \u2013 North Bristol NHS Trust, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gita","family":"Gramizadeh-Naeini","sequence":"first","affiliation":[{"name":"Stroke Department, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10397","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"10.12890\/2025_006016_ref1","unstructured":"Ann MY, Liu OK, Wu YL. Foix-Chavany-Marie syndrome. Zhonghua Yi Xue Za Zhi (Taipei) 2001;64:540-544."},{"key":"10.12890\/2025_006016_ref2","doi-asserted-by":"crossref","unstructured":"Weller M. Anterior opercular cortex lesions cause dissociated lower cranial nerve palsies and anarthria but no aphasia: Foix-Chavany-Marie syndrome and \u201cautomatic voluntary dissociation\u201d revisited. J Neurol 1993;240:199\u2013208. doi: 10.1007\/BF00818705","DOI":"10.1007\/BF00818705"},{"key":"10.12890\/2025_006016_ref3","doi-asserted-by":"crossref","unstructured":"S\u00e1 F, Menezes Cordeiro I, Mestre S, Nzwalo H. Unilateral opercular infarction presenting with Foix-Chavany-Marie syndrome. BMJ Case Rep 2014;2014:bcr2014204238. doi: 10.1136\/bcr-2014-206439","DOI":"10.1136\/bcr-2014-206439"},{"key":"10.12890\/2025_006016_ref4","doi-asserted-by":"crossref","unstructured":"Hopf HC, M\u00fcller-Forell W, Hopf NJ. Localization of emotional and volitional facial paresis. Neurology 1992;42:1918-23. doi: 10.1212\/wnl.42.10.1918","DOI":"10.1212\/WNL.42.10.1918"},{"key":"10.12890\/2025_006016_ref5","unstructured":"Lekhjung T, Raju P, Rijal PVS. Opercular syndrome: case reports and review of literature. Neurol Asia 2010;15:145\u2013152."},{"key":"10.12890\/2025_006016_ref6","doi-asserted-by":"crossref","unstructured":"Shoji R, Kono Y, Furuhashi H, Nakano M, Torisu Y. Foix-Chavany-Marie syndrome induced by a unilateral brain abscess. Intern Med 2019;58:581\u2013583. doi: 10.2169\/internalmedicine","DOI":"10.2169\/internalmedicine.1500-18"},{"key":"10.12890\/2025_006016_ref7","doi-asserted-by":"crossref","unstructured":"Zaheer T. Unmasking bilateral opercular syndrome: a rare case of Foix\u2013Chavany\u2013Marie syndrome. Int J Sci Res Publ 2025;15:41\u201347. doi: 10.29322\/IJSRP.15.08.2025.p16407","DOI":"10.29322\/IJSRP.15.08.2025.p16407"},{"key":"10.12890\/2025_006016_ref8","doi-asserted-by":"crossref","unstructured":"Mateos V, Salas-Puig J, Campos DM, Carrero V, Andermann F. Acquired bilateral opercular lesions or Foix-Chavany-Marie syndrome and eating epilepsy. J Neurol Neurosurg Psychiatry 1995;59:559-560. doi: 10.1136\/jnnp.59.5.559-a","DOI":"10.1136\/jnnp.59.5.559-a"},{"key":"10.12890\/2025_006016_ref9","unstructured":"Qiu X, Zhang B, Chen C, Gao T, Sun C, et al. Recovery of Foix-Chavany-Marie syndrome with multi-modal rehabilitation therapy: a case report and review of literature. J Trauma Treat 2019;8:445. doi: 10.4172\/2167-1222.1000445"},{"key":"10.12890\/2025_006016_ref10","doi-asserted-by":"crossref","unstructured":"Rivas K, Pan J, Chen A, Guti\u00e9rrez B, Julayanont P. Foix-Chavany-Marie syndrome due to unilateral anterior opercular infarction with leukoaraiosis. Proc (Bayl Univ Med Cent) 2021;34:389-390. doi: 10.1080\/08998280.2021.1878976","DOI":"10.1080\/08998280.2021.1878976"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/6016\/5023","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/6016\/5024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/6016\/5024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T13:52:35Z","timestamp":1767966755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/6016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,22]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.12890\/2025_006016","relation":{"has-manifestation":[{"id-type":"other","id":"1-133-6016-g5023","asserted-by":"subject"},{"id-type":"other","id":"1-133-6016-g5024","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-133","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,22]]}}}