{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:49Z","timestamp":1756425769056,"version":"3.44.0"},"reference-count":5,"publisher":"SMC Media","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>The authors present the case of a 65-year-old Caucasian man who had previously lived in Guinea-Bissau. The patient was diagnosed in Portugal with an anti-neutrophil cytoplasmic antibody-associated vasculitis and started on corticosteroids plus cyclophosphamide, with clinical improvement. Some months later, his general status deteriorated, iatrogenic bicytopenia developed and immunosuppressive drugs were tapered. Microbiological tests identified numerous larvae and eggs of Strongyloides stercoralis in various biological samples, and a diagnosis of hyperinfection syndrome was established. The patient was started on antihelminthic drugs but developed septic shock and died. This case highlights a rare and severe complication of immunosuppression in developed countries.<\/jats:p>","DOI":"10.12890\/2015_000286","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T09:52:37Z","timestamp":1621936357000},"source":"Crossref","is-referenced-by-count":1,"title":["Strongyloides stercoralis - a Legacy from the Past"],"prefix":"10.12890","volume":"2","author":[{"given":"In\u00eas","family":"Chora","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de S\u00e3o Jo\u00e3o"}]},{"given":"Rodrigo","family":"Pimentel","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de S\u00e3o Jo\u00e3o"}]},{"given":"Fernando","family":"Fri\u00f5es","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de S\u00e3o Jo\u00e3o"}]},{"given":"Paula","family":"Dias","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de S\u00e3o Jo\u00e3o"}]},{"given":"S\u00e9rgio","family":"Silva","sequence":"additional","affiliation":[{"name":"Centro Hospitalar de S\u00e3o Jo\u00e3o"}]}],"member":"10397","published-online":{"date-parts":[[2015,10,16]]},"reference":[{"key":"10.12890\/2015_000286_ref1","doi-asserted-by":"crossref","unstructured":"Villa-Forte A, European League Against Rheumatism\/European Vasculitis Study Group. European League Against Rheumatism\/European Vasculitis Study Group recommendations for the management of vasculitis.<em> Curr Opin Rheumatol <\/em>2010;<strong>22<\/strong>:49\u201353.","DOI":"10.1097\/BOR.0b013e328332c9d1"},{"key":"10.12890\/2015_000286_ref2","doi-asserted-by":"crossref","unstructured":"Greaves D, Coggle S, Pollard C, Aliyu SH, Moore EM. Strongyloides stercoralis infection.<em> BMJ <\/em>2013;<strong>347<\/strong>:f4610.","DOI":"10.1136\/bmj.f4610"},{"key":"10.12890\/2015_000286_ref3","unstructured":"Kassalik M, M\u00f6nkem\u00fcller K. Strongyloides stercoralis hyperinfection syndrome and disseminated disease. <em>Gastroenterol Hepatol<\/em> 2011;<strong>7<\/strong>:766\u2013768."},{"key":"10.12890\/2015_000286_ref4","doi-asserted-by":"crossref","unstructured":"Pukkila-Worley R, Nardi V, Branda JA. Case records of the Massachusetts General Hospital. Case 28-2014. A 39-year-old man with a rash, headache, fever, nausea, and photophobia.<em> N Engl J Med<\/em> 2014;<strong>371<\/strong>:1051\u20131060.","DOI":"10.1056\/NEJMcpc1405886"},{"key":"10.12890\/2015_000286_ref5","doi-asserted-by":"crossref","unstructured":"Montes M, Sawhney C, Barros N. <em>Strongyloides stercoralis<\/em>: there but not seen. <em>Curr Opin Infect Dis<\/em> 2010;<strong>23<\/strong>:500\u2013504.","DOI":"10.1097\/QCO.0b013e32833df718"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/286\/484","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/286\/485","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/286\/485","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:24:49Z","timestamp":1756365889000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,16]]},"references-count":5,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.12890\/2015_000286","relation":{"has-manifestation":[{"id-type":"other","id":"1-10-286-g484","asserted-by":"subject"},{"id-type":"other","id":"1-10-286-g485","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-10","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"type":"electronic","value":"2284-2594"}],"subject":[],"published":{"date-parts":[[2015,10,16]]},"article-number":"2"}}