{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T01:50:22Z","timestamp":1772502622511,"version":"3.50.1"},"reference-count":7,"publisher":"SMC Media","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:p>Acute copper toxicity is uncommon in Western countries and is often the result of accidental consumption or a suicide attempt. We report the case of a 65-year-old man presenting to the accident and emergency department after a suicide attempt with ingestion of Bordeaux mixture, ibuprofen, acetaminophen and bleach. Primary evaluation showed caustic oesophagitis, toxic hepatitis and acute renal injury, which were treated with supportive care. During admission, he developed a non-immune haemolytic anaemia associated with high levels of copper in urine and blood. Chelation treatment with penicillamine was started and evolution was favourable after 1 month of treatment. Copper poisoning can be lethal. Prompt diagnosis and treatment are key for a favourable prognosis.<\/jats:p>","DOI":"10.12890\/2021_002785","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T03:33:36Z","timestamp":1630985616000},"source":"Crossref","is-referenced-by-count":3,"title":["Copper-induced Haemolytic Anaemia"],"prefix":"10.12890","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4405-3302","authenticated-orcid":false,"given":"Joana","family":"Azevedo Carvalho","sequence":"additional","affiliation":[{"name":"Hospital Prof. Dr. Fernando Fonseca \u2013 Medicina IV, Amadora, Portugal"}]},{"given":"Leonor","family":"Boavida","sequence":"additional","affiliation":[{"name":"Hospital Prof. Dr. Fernando Fonseca \u2013 Medicina IV, Amadora, Portugal"}]},{"given":"Ricardo","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Hospital Prof. Dr. Fernando Fonseca \u2013 Oncologia, Amadora, Portugal"}]},{"given":"Catarina","family":"Favas","sequence":"additional","affiliation":[{"name":"Hospital Prof. Dr. Fernando Fonseca \u2013 Medicina IV, Amadora, Portugal"}]},{"given":"Jos\u00e9","family":"Delgado Alves","sequence":"additional","affiliation":[{"name":"Hospital Prof. Dr. Fernando Fonseca \u2013 Medicina IV, Amadora, Portugal"}]}],"member":"10397","published-online":{"date-parts":[[2021,10,8]]},"reference":[{"key":"10.12890\/2021_002785_ref1","doi-asserted-by":"crossref","unstructured":"<li>Agrios GN. Control of plant diseases. In: Plant pathology. 5th ed. Amsterdam: Elsevier; 2005, chapter 9. <\/li>","DOI":"10.1016\/B978-0-08-047378-9.50015-4"},{"key":"10.12890\/2021_002785_ref2","doi-asserted-by":"crossref","unstructured":"<li>Sonal Sekhar M, Rao M. Clinical toxicology of copper: source, toxidrome, mechanism of toxicity, and management. In: Bagchi D, Bagchi M, editors. Metal toxicology handbook. Boca Raton: CRC Press; 2020, pp. 199\u2013217.<\/li>","DOI":"10.1201\/9780429438004-19"},{"key":"10.12890\/2021_002785_ref3","unstructured":"<li>Moussiegt A, Ferreira L, Aboab J, Silva D. She has the blues: an unusual case of copper sulphate intoxication. <em>EJCRIM<\/em> 2020;<strong>7<\/strong>(2):001394.<\/li>"},{"key":"10.12890\/2021_002785_ref4","doi-asserted-by":"crossref","unstructured":"<li>Higny J, Vanpee D, Boulouffe C. Bluish vomiting: a rare clinical presentation of poisoning. <em>Acta Clin Belg<\/em> 2014;<strong>69<\/strong>(4):299\u2013301.<\/li>","DOI":"10.1179\/2295333714Y.0000000033"},{"key":"10.12890\/2021_002785_ref5","unstructured":"<li>Royer A, Sharman T. Copper toxicity. [Updated 2021 Apr 3]. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK557456\/<\/li>"},{"key":"10.12890\/2021_002785_ref6","doi-asserted-by":"crossref","unstructured":"<li>Saravu K, Jose J, Bhat M, Jimmy B, Shastry B. Acute ingestion of copper sulphate: a review on its clinical manifestations and management. <em>Indian J Crit Care Med<\/em> 2007;<strong>11<\/strong>:74\u201380.<\/li>","DOI":"10.4103\/0972-5229.33389"},{"key":"10.12890\/2021_002785_ref7","unstructured":"<li>World Health Organization. Suicide. Available from: https:\/\/www.euro.who.int\/en\/health-topics\/noncommunicable-diseases\/mental-health\/areas-of-work\/suicide (accessed 14 July 2021).<\/li>"}],"container-title":["European Journal of Case Reports in Internal Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2785\/2825","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2785\/2826","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/download\/2785\/2826","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T13:27:09Z","timestamp":1756128429000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ejcrim.com\/index.php\/EJCRIM\/article\/view\/2785"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,8]]},"references-count":7,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.12890\/2021_002785","relation":{"has-manifestation":[{"id-type":"other","id":"1-77-2785-g2825","asserted-by":"subject"},{"id-type":"other","id":"1-77-2785-g2826","asserted-by":"subject"}],"is-part-of":[{"id-type":"other","id":"1-77","asserted-by":"subject"}]},"ISSN":["2284-2594"],"issn-type":[{"value":"2284-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,8]]},"article-number":"11"}}