{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:27:20Z","timestamp":1774466840871,"version":"3.50.1"},"reference-count":30,"publisher":"Japanese Society of Hypertension","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hypertens Res"],"published-print":{"date-parts":[[2008]]},"DOI":"10.1291\/hypres.31.127","type":"journal-article","created":{"date-parts":[[2008,3,21]],"date-time":"2008-03-21T05:52:06Z","timestamp":1206078726000},"page":"127-133","source":"Crossref","is-referenced-by-count":6,"title":["Chronic Insulin Infusion Normalizes Blood Pressure and the Gene Expressions of Angiotensin II Type 1 Receptor in Fructose-Fed Rats"],"prefix":"10.1291","volume":"31","author":[{"given":"Tomoyasu","family":"FUKUI","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"HIRANO","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"SHIRAISHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaharu","family":"NAGASHIMA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"ADACHI","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"119","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Rowe JW, Young JB, Minaker KL, et al<\/i>: Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes<\/i> 1981; 30<\/b>: 219-225.","DOI":"10.2337\/diab.30.3.219"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. DeFronzo RA: The effect of insulin on renal sodium metabolism. A review with clinical implications. Diabetologia<\/i> 1981; 21<\/b>: 165-171.","DOI":"10.1007\/BF00252649"},{"issue":"3","key":"3","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1161\/01.HYP.32.3.482","volume":"32","author":"KAMIDE K","year":"1998","ISSN":"https:\/\/id.crossref.org\/issn\/0194-911X","issn-type":"print"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Vettor R, Mazzonetto P, Macor C, et al<\/i>: Effect of endogenous organic hyperinsulinaemia on blood pressure and serum triglycerides. Eur J Clin Invest<\/i> 1994; 24<\/b>: 350-354.","DOI":"10.1111\/j.1365-2362.1994.tb01096.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Leonetti F, Iozzo P, Giaccari A, et al<\/i>: Absence of clinically overt atherosclerotic vascular disease and adverse changes in cardiovascular risk factors in 70 patients with insulinoma. J Endocrinol Invest<\/i> 1993; 16<\/b>: 875-880.","DOI":"10.1007\/BF03348949"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Hwang IS, Ho H, Hoffman BB, et al<\/i>: Fructose-induced insulin resistance and hypertension in rats. Hypertension<\/i> 1987; 10<\/b>: 512-516.","DOI":"10.1161\/01.HYP.10.5.512"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.26.169"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.27.293"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000111136.86976.26"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Catena C, Giacchetti G, Novello M, et al<\/i>: Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension. Am J Hypertens<\/i> 2003; 16<\/b>: 973-978.","DOI":"10.1016\/S0895-7061(03)01002-1"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Katovich MJ, Reaves PY, Francis SC, et al<\/i>: Gene therapy attenuates the elevated blood pressure and glucose intolerance in an insulin-resistant model of hypertension. J Hypertens<\/i> 2001; 19<\/b>: 1553-1558.","DOI":"10.1097\/00004872-200109000-00006"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200018060-00006"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Nickenig G, Roling J, Strehlow K, et al<\/i>: Insulin induces upregulation of vascular AT1 receptor gene expression by posttranscriptional mechanisms. Circulation<\/i> 1998; 98<\/b>: 2453-2460.","DOI":"10.1161\/01.CIR.98.22.2453"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Ran J, Hirano T, Adachi M: Chronic ANG II infusion increases plasma triglyceride level by stimulating hepatic triglyceride production in rats. Am J Physiol Endocrinol Metab<\/i> 2004; 287<\/b>: E955-E961.","DOI":"10.1152\/ajpendo.00199.2004"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Hsieh PS: Attenuation of insulin-mediated pressor effect and nitric oxide release in rats with fructose-induced insulin resistance. Am J Hypertens<\/i> 2004; 17<\/b>: 707-711.","DOI":"10.1016\/j.amjhyper.2004.04.006"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Bursztyn M, Mekler J, Peleg E, et al<\/i>: Subpressor dose of L-NAME unmasks hypertensive effect of chronic hyperinsulinemia. Hypertension<\/i> 2000; 36<\/b>: 872-877.","DOI":"10.1161\/01.HYP.36.5.872"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Kahiwagi A, Shinozaki K, Nishio Y, et al<\/i>: Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats. Am J Physiol Endocrinol Metab<\/i> 1999; 277<\/b>: E976-E983.","DOI":"10.1152\/ajpendo.1999.277.6.E976"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Juan C-C, Shen Y-W, Chien Y, et al<\/i>: Insulin infusion induces endothelin-1−dependent hypertension in rats. Am J Physiol Endocrinol Metab<\/i> 2004; 287<\/b>: E948-E954.","DOI":"10.1152\/ajpendo.00536.2003"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Fang T-C, Wu C-C, Huang WC: Inhibition of nitric oxide synthesis accentuates blood pressure elevation in hyperinsulinemic rats. J Hypertens<\/i> 2001; 19<\/b>: 1255-1262.","DOI":"10.1097\/00004872-200107000-00010"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Sundell J, Nuutila P, Laine H, et al<\/i>: Dose-dependent vasodilating effects of insulin on adenosine-stimulated myocardial blood flow. Diabetes<\/i> 2002; 51<\/b>: 1125-1130.","DOI":"10.2337\/diabetes.51.4.1125"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Ter Maaten JC, Bakker SJ, Serne EH, et al<\/i>: Insulin-mediated increases in renal plasma flow are impaired in insulin-resistant normal subjects. Eur J Clin Invest<\/i> 2000; 30<\/b>: 1090-1098.","DOI":"10.1046\/j.1365-2362.2000.00749.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000082806.73530.68"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Fisslthaler B, Benzing T, Busse R, et al<\/i>: Insulin enhances the expression of the endothelial nitric oxide synthase in native endothelial cells: a dual role for Akt and AP-1. Nitric Oxide<\/i> 2003; 8<\/b>: 253-261.","DOI":"10.1016\/S1089-8603(03)00042-9"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Scherrer U, Randin D, Vollenweider P, et al<\/i>: Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest<\/i> 1994; 94<\/b>: 2511-2515.","DOI":"10.1172\/JCI117621"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.12.2437"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Reed MJ, Ho H, Donnelly R, et al<\/i>: Salt-sensitive and carbohydrate-sensitive rodent hypertension: evidence of strain differences. Blood Pressure<\/i> 1994; 3<\/b>: 197-201.","DOI":"10.3109\/08037059409102253"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1291\/hypres.24.127"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Iyer SN, Raizada MK, Katovich MJ: AT1 receptor density changes during development of hypertension in hyperinsulinemic rats. Clin Exp Hypertens<\/i> 1996; 18<\/b>: 793-810.","DOI":"10.3109\/10641969609081781"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(99)00301-5"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Reaven GM, Ho H, Hoffmann BB: Somatostatin inhibition of fructose-induced hypertension. Hypertension<\/i> 1989; 14<\/b>: 117-120.","DOI":"10.1161\/01.HYP.14.2.117"}],"container-title":["Hypertension Research"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T09:45:01Z","timestamp":1557395101000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nature.com\/doifinder\/10.1291\/hypres.31.127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1291\/hypres.31.127","relation":{},"ISSN":["0916-9636","1348-4214"],"issn-type":[{"value":"0916-9636","type":"print"},{"value":"1348-4214","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008]]}}}