{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T15:30:45Z","timestamp":1788622245450,"version":"build-2803163510"},"reference-count":39,"publisher":"Japanese Society of Veterinary Science","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1292\/jvms.12-0163","type":"journal-article","created":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T22:55:17Z","timestamp":1364856917000},"page":"1035-1040","source":"Crossref","is-referenced-by-count":17,"title":["&lt;i&gt;In Vitro&lt;\/i&gt; Antimicrobial Susceptibility of &lt;i&gt;Brucella melitensis&lt;\/i&gt; Isolates from Sheep in an Area Endemic for Human Brucellosis in Turkey"],"prefix":"10.1292","volume":"75","author":[{"given":"Ziya","family":"ILHAN","sequence":"first","affiliation":[{"name":"Department of Microbiology, Faculty of Veterinary Medicine, Yuzuncu Yil University, 65080 Van, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"SOLMAZ","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Yuzuncu Yil University, 65080 Van, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail Hakki","family":"EKIN","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Faculty of Veterinary Medicine, Yuzuncu Yil University, 65080 Van, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"122","reference":[{"key":"1","unstructured":"1. Akdeniz, H., Irmak, H. and Demiroz, A. P. 1998. Evaluation of brucellosis cases in Van region of western Anatolia: a-3 year experience. Nagoya Med. J. 42: 101&ndash;110."},{"key":"2","unstructured":"2. Al\u0131skan, H., Turunc, T., Demiroglu, Y. Z., Colakoglu, S. and Arslan, H. 2008. Investigation of <i>in vitro<\/i> antibiotic susceptibility of <i>Brucella melitensis<\/i>. Microbiol. Bul. 42: 125&ndash;129 (in Turkish)."},{"key":"3","unstructured":"3. Alton, G. G., Jones, L. M., Angus, R. D. and Verger, J. M. 1988. Bacteriological methods. pp. 13&ndash;61. <i>In<\/i>: Techniques for the Brucellosis Laboratory, Institute National de la Recherche Agronomique, Paris."},{"key":"4","unstructured":"4. Altun, B., Hascelik, G. and Gur, D. 2009. <i>In vitro<\/i> activity of tigecycline against <i>Brucella<\/i> spp. Med. J. Trakya Univ. 26: 261&ndash;263."},{"key":"5","unstructured":"5. Arda, M., Bisping, W., Ayd\u0131n, N., Istanbulluoglu, E., Akay, O., Izgur, M., Diker, K. S. and Karaer, Z. 1987. An etiologic and serologic investigation of ovine abortion in Central Anatolia Region. Vet. J. Ankara Univ. 34: 195&ndash;206."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Ariza, J., Bosilkovski, M., Cascio, A., Colmenero, J. D., Corbel, M. J., Falagas, M. E., Memish, Z. A., Roushan, M. R. H., Rubinstein, E., Sipsas, N. V., Solera, J., Young, E. J. and Pappas, G. 2007. Perspective for the treatment of brucellosis in the 21st century: the loannina recommendations. PLoS Med. 4: 1872&ndash;1878.","DOI":"10.1371\/journal.pmed.0040317"},{"key":"7","unstructured":"7. Ayaslioglu, E., K\u0131l\u0131c, S., Ayd\u0131n, K., K\u0131l\u0131c, D., Kaygusuz, S. and Agalar, C. 2008. Antimicrobial susceptibility of <i>Brucella melitensis<\/i> isolates from blood samples. Turk. J. Med. Sci. 38: 257&ndash;262."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Bauer, A. U., Kirby, W. M., Sherris, J. C. and Tack, M. 1966. Antibiotic susceptibility testing by a standardized single disc method. J. Clin. Pathol. 45: 493&ndash;494.","DOI":"10.1093\/ajcp\/45.4_ts.493"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Baykam, N., Esener, H., Ergonul, O., Eren, S., Celikbas, A. K. and Dokuzoguz, B. 2004. <i>In vitro<\/i> antimicrobial susceptibility of <i>Brucella<\/i> species. Int. J. Antimicrob. Agents 23: 405&ndash;407.","DOI":"10.1016\/j.ijantimicag.2003.09.024"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Bayram, Y., Korkoca, H., Aypak, C., Parlak, M., Cikman, A., K\u0131l\u0131c, S. and Berktas, M. 2011. Antimicrobial susceptibilities of <i>Brucella<\/i> isolates from various clinical specimens. Int. J. Med. Sci. 8: 198&ndash;202.","DOI":"10.7150\/ijms.8.198"},{"key":"11","unstructured":"11. Bricker, B. J. and Halling, S. M. 1994. Differentiation of <i>Brucella abortus<\/i> bv. 1, 2 and 4, <i>Brucella melitensis, Brucella ovis<\/i> and <i>Brucella suis<\/i> bv. 1 by PCR. J. Clin. Microbiol. 32: 2660&ndash;2666."},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Buzgan, T., Karahocagil, M. K., Irmak, H., Baran, A. I., Karsen, H., Evirgen, O. and Akdeniz, H. 2010. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int. J. Infect. Dis. 14: e469&ndash;e478.","DOI":"10.1016\/j.ijid.2009.06.031"},{"key":"13","unstructured":"13. Esel, D., Doganay, M., Alp, E. and Sumerkan, B. 2003. Prospective evaluation of blood cultures in a Turkish university hospital: epidemiology, microbiology and patient outcome. Clin. Microbiol. Infect. 9: 1038&ndash;1044."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Falagas, M. E. and Bliziotis, I. A. 2006. Minireview: quinolones for treatment of human brucellosis: critical review of the evidence from microbiological and clinical studies. Antimicrob. Agents Chemother. 50: 22&ndash;33.","DOI":"10.1128\/AAC.50.1.22-33.2006"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Franco, M. P., Mulder, M., Gilman, R. H. and Smits, H. L. 2007. Human brucellosis. Lancet Infect. Dis. 7: 775&ndash;786.","DOI":"10.1016\/S1473-3099(07)70286-4"},{"key":"16","unstructured":"16. Gurturk, K., Aksakal, A. and Baydas, B. 1995. Etiological and serological examinations on brucellosis in aborted sheep in Van region. J. Health Sci. U.Y.Y. 2: 13&ndash;15."},{"key":"17","unstructured":"17. Ilhan, Z., Solmaz, H., Aksakal, A., Gulhan, T., Ekin, I. H. and Boynukara, B. 2007. Comparison of PCR assay and bacteriological culture method for the detection of <i>Brucella melitensis<\/i> in stomach content samples of aborted sheep fetuses. Dtsch. Tierarztl. Wochenschr. 114: 460&ndash;464."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Irmak, H., Buzgan, T., Evirgen, O., Akdeniz, H., Demir&ouml;z, A. P., Abdoel, T. H. and Smits, H. L. 2004. Use of the <i>Brucella<\/i> IgM and IgG flow assays in the serodiagnosis in an area endemic for brucellosis. Am. J. Trop. Med. Hyg. 70: 688&ndash;694.","DOI":"10.4269\/ajtmh.2004.70.688"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Kaya, O., Akcam, F. Z. and Yayl\u0131, G.2012. Investigation of the <i>in vitro<\/i> activities of various antibiotics against <i>Brucella melitensis<\/i> strains. Turk. J. Med. Sci. 42: 145&ndash;148.","DOI":"10.3906\/sag-1009-1129"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kinsara, A., Al-Mowallad, A. and Osoba, A. O. 1999. Increasing resistance of <i>Brucellae<\/i> to co-trimoxazole. Antimicrob. Agents Chemother. 43: 1531.","DOI":"10.1128\/AAC.43.6.1531"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Leal-Klevezas, D. S., Martinez-Vazquez, O. I., Lo&rsquo;pez-Merino, A. and Martinez-Soriano, J. P. 1995. Single-step PCR for detection of <i>Brucella<\/i> spp. from blood and milk of infected animals. J. Clin. Microbiol. 33: 3087&ndash;3090.","DOI":"10.1128\/JCM.33.12.3087-3090.1995"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Leyla, G., Kadri, G. and Umran, O. 2003. Comparison of polymerase chain reaction and bacteriological culture for the diagnosis of sheep brucellosis using aborted fetus samples. Vet. Microbiol. 93: 53&ndash;61.","DOI":"10.1016\/S0378-1135(02)00442-X"},{"key":"23","unstructured":"23. Lopez-Merino, A., Contreras-Rodriguez, A., Migranas-Ortiz, R., Orrantia-Gradin, R., Hernandez-Oliva, G. M., Guttierrez-Rubio, A. T. and Cardenosa, O. 2004. Susceptibility of Mexican <i>Brucella<\/i> isolates to moxifloxacin, ciprofloxacin and other antimicrobials used in the treatment of human brucellosis. Scand. J. Infect. Dis. 36: 636&ndash;638."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Marianelli, C., Ciuchini, F., Tarantino, M., Pasquali, P. and Adone, R. 2004. Genetic bases of the rifampicin resistance phenotype in <i>Brucella<\/i> spp. J. Clin. Microbiol. 42: 5439&ndash;5443.","DOI":"10.1128\/JCM.42.12.5439-5443.2004"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Marianelli, C., Graziani, C., Santangelo, C., Xibilia, M. T., Imbriani, A., Amato, R., Neri, D., Cuccia, M., Rinnone, S., Di Marco, V. and Ciuchini, F. 2007. Molecular epidemiological and antibiotic susceptibility characterization of <i>Brucella<\/i> isolates from humans in Sicily, Italy. J. Clin. Microbiol. 45: 2923&ndash;2928.","DOI":"10.1128\/JCM.00822-07"},{"key":"26","unstructured":"26. Members of the SFM Antibiogram Committee. 2003. Comit&eacute; de l&rsquo;antibiogramme de la soci&eacute;t&eacute; franc,aise de microbiologie report 2003, members of the SFM antibiogram committee. Int. J. Antimicrob. Agents 21: 364&ndash;391."},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Memish, Z., Mah, M. W., Al Mahmoud, S., Al Shaalan, M. and Khan, M. Y. 2000. <i>Brucella<\/i> bacteraemia: clinical and laboratory observations in 160 patients. J. Infect. 40: 59&ndash;63.","DOI":"10.1053\/jinf.1999.0586"},{"key":"28","unstructured":"28. National Committe for Clinical Laboratory Standards. 2007. Performance Standards for Antimicrobial Susceptibility Testing. Eighteenth Informational Supplement. Document M100-S18, PA: NCCLS, Wayne."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Pappas, G., Solera, J., Akritidis, N. and Tsianos, E. 2005. New approaches to the antibiotic treatment of brucellosis. Int. J. Antimicrob. Agents 26: 101&ndash;105.","DOI":"10.1016\/j.ijantimicag.2005.06.001"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Pappas, G., Papadimitriou, P., Akritidis, N., Christou, L. and Tsianos, E. V. 2006. The new global map of human brucellosis. Lancet Infect. Dis. 6: 91&ndash;99.","DOI":"10.1016\/S1473-3099(06)70382-6"},{"key":"31","unstructured":"31. Quinn, P. J., Carter, M. E., Markey, B. K. and Carter, G. R. 1994. Corynebacterium species and <i>Rhodococcus equi<\/i>, the actiomycetes, mycobacterium species. pp. 137&ndash;169. <i>In<\/i>: Clinical Veterinary Microbiology, Mosby International Ltd., Barcelona."},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Radwan, A. I., Bekairi, S. I. and Mukayel, A. A. 1992. Treatment of <i>Brucella melitensis<\/i> infection in sheep and goats with oxytetracycline combined with streptomycin. Rev. Sci. Tech. 11: 845&ndash;857.","DOI":"10.20506\/rst.11.3.630"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Radwan, A. I., Bekairi, S. I., Mukayel, A. A., Al-Bokmy, A. M., Prasad, P. V., Azar, F. N. and Coloyan, E. R. 1995. Control of <i>Brucella melitensis<\/i> infection in a large camel herd in Saudi Arabia using antibiotherapy and vaccination with Rev. 1 vaccine. Rev. Sci. Tech. 14: 719&ndash;732.","DOI":"10.20506\/rst.14.3.860"},{"key":"34","doi-asserted-by":"crossref","unstructured":"34. Sayan, M., Kilic, S. and Uyan\u0131k, M. H. 2012. Epidemiological survey of rifampicin resistance in clinic isolates of <i>Brucella melitensis<\/i> obtained from all regions of Turkey. J. Infect. Chemother. 18: 41&ndash;46.","DOI":"10.1007\/s10156-011-0281-7"},{"key":"35","unstructured":"35. Turan, H., Arslan, H., Uncu, H., Azap, O. and Serefhanoglu, K. 2007. <i>In vitro<\/i> activity of tigecycline against <i>Brucella<\/i> strains: a comparative study with doxycycline, ciprofloxacin and rifampin. Turk. J. Infect. 21: 147&ndash;151."},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Vancelik, S., Guraksin, A. and Ayyildiz, A. 2008. Seroprevalence of human brucellosis in rural endemic areas in eastern Turkey. Trop. Doct. 38: 42&ndash;43.","DOI":"10.1258\/td.2007.060004"},{"key":"37","unstructured":"37. World Health Organization. 2006. World Health Organization in Collaboration with the Food and Agriculture Organization of the United Nations and World Organisation for Animal Health (WHO\/CDS\/EPR\/2006.7), Brucellosis in Humans and Animals. pp. 1&ndash;89. WHO Press, Geneva."},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Yamazhan, T., Aydemir, S., Tunger, A., Serter, D. and Gokengin, D. 2005. <i>In vitro<\/i> activities of various antimicrobials against <i>Brucella melitensis<\/i> strains in the Aegean Region in Turkey. Med. Princ. Pract. 14: 413&ndash;416.","DOI":"10.1159\/000088122"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Young, E. J. 1983. Human brucellosis. Rev. Infect. Dis. 5: 821&ndash;842.","DOI":"10.1093\/clinids\/5.5.821"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/8\/75_12-0163\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T19:29:13Z","timestamp":1688153353000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/8\/75_12-0163\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":39,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.12-0163","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}