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Aguirre-Hernandez, J., Milne, B. S., Queen, C., O&rsquo;Brien, P. C., Hoather, T., Haugland, S., Ferguson-Smith, M. A., Dobson, J. M. and Sargan, D. R. 2009. Disruption of chromosome 11 in canine fibrosarcomas highlights an unusual variability of CDKN2B in dogs. BMC Vet. Res. 5: 27.","DOI":"10.1186\/1746-6148-5-27"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Amara, K., Trimeche, M., Ziadi, S., Laatiri, A., Hachana, M. and Korbi, S. 2008. Prognostic significance of aberrant promoter hypermethylation of CpG islands in patients with diffuse large B-cell lymphomas. Ann. Oncol. 19: 1774&ndash;1786.","DOI":"10.1093\/annonc\/mdn374"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Baur, A. S., Shaw, P., Burri, N., Delacretaz, F., Bosman, F. T. and Chaubert, P. 1999. Frequent methylation silencing of p15(INK4b) (MTS2) and p16(INK4a) (MTS1) in B-cell and T-cell lymphomas. 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Hangaishi, A., Ogawa, S., Imamura, N., Miyawaki, S., Miura, Y., Uike, N., Shimazaki, C., Emi, N., Takeyama, K., Hirosawa, S., Kamada, N., Kobayashi, Y., Takemoto, Y., Kitani, T., Toyama, K., Ohtake, S., Yazaki, Y., Ueda, R. and Hirai, H. 1996. Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1\/p16INK4A\/CDKN2, MTS2\/p15INK4B, p53, and Rb genes in primary lymphoid malignancies. Blood 87: 4949&ndash;4958."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S. and Peters, G. 1996. Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol. 16: 859&ndash;867.","DOI":"10.1128\/MCB.16.3.859"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.769"},{"key":"16","unstructured":"16. Hutter, G., Scheubner, M., Zimmermann, Y., Kalla, J., Katzenberger, T., Hubler, K., Roth, S., Hiddemann, W., Ott, G. and Dreyling, M. 2006. Differential effect of epigenetic alterations and genomic deletions of CDK inhibitors [p16(INK4a), p15(INK4b), p14(ARF)] in mantle cell lymphoma. Genes Chromosomes Cancer 45: 203&ndash;210."},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-10-247122"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Kees, U. R., Terry, P. A., Ford, J., Everett, J., Murch, A., De Klerk, N. and Baker, D. L. 2005. Detection of hemizygous deletions in genomic DNA from leukaemia specimens for the diagnosis of patients. Leuk. Res. 29: 165&ndash;171.","DOI":"10.1016\/j.leukres.2004.05.021"},{"key":"19","unstructured":"19. Kim, M., Yim, S. H., Cho, N. S., Kang, S. H., Ko, D. H., Oh, B., Kim, T. Y., Min, H. J., She, C. J., Kang, H. J., Shin, H. Y., Ahn, H. S., Yoon, S. S., Kim, B. K., Shin, H. R., Han, K. S., Cho, H. I. and Lee, D. S. 2009. 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Kohno, T., Yamada, Y., Tawara, M., Takasaki, Y., Kamihira, S., Tomonaga, M. and Matsuyama, T. 2007. Inactivation of p14ARF as a key event for the progression of adult T cell leukemia\/lymphoma. Leuk. Res. 31: 1625&ndash;1632.","DOI":"10.1016\/j.leukres.2006.12.007"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1205322"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Lee, S. M., Lee, E. J., Ko, Y. H., Lee, S. H., Maeng, L. and Kim, K. M. 2009. Prognostic significance of O6-methylguanine DNA methyltransferase and p57 methylation in patients with diffuse large B-cell lymphomas. APMIS 117: 87&ndash;94.","DOI":"10.1111\/j.1600-0463.2008.00017.x"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1021\/bi200642e"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Masumoto, N., Fujii, T., Ishikawa, M., Saito, M., Iwata, T., Fukuchi, T., Susumu, N., Mukai, M., Kubushiro, K., Tsukazaki, K. and Nozawa, S. 2003. P16 overexpression and human papillomavirus infection in small cell carcinoma of the uterine cervix. Hum. Pathol. 34: 778&ndash;783.","DOI":"10.1016\/S0046-8177(03)00284-3"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Modiano, J. F., Breen, M., Valli, V. E., Wojcieszyn, J. W. and Cutter, G. R. 2007. Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin&rsquo;s lymphoma. Leukemia 21: 184&ndash;187.","DOI":"10.1038\/sj.leu.2404392"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(97)00053-6"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.58.469"},{"key":"30","unstructured":"30. Omura-Minamisawa, M., Diccianni, M. B., Batova, A., Chang, R. C., Bridgeman, L. J., Yu, J., Pullen, J., Bowman, W. P. and Yu, A. L. 2000. Universal inactivation of both p16 and p15 but not downstream components is an essential event in the pathogenesis of T-cell acute lymphoblastic leukemia. Clin. Cancer Res. 6: 1219&ndash;1228."},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Parry, D., Bates, S., Mann, D. J. and Peters, G. 1995. Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4\/MTS1 tumour suppressor gene product. EMBO J. 14: 503&ndash;511.","DOI":"10.1002\/j.1460-2075.1995.tb07026.x"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Popov, N. and Gil, J. 2010. Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in health. Epigenetics 5: 685&ndash;690.","DOI":"10.4161\/epi.5.8.12996"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Russo, A. A., Tong, L., Lee, J. O., Jeffrey, P. D. and Pavletich, N. P. 1998. Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature 395: 237&ndash;243.","DOI":"10.1038\/26155"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2010.01.021"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81079-X"},{"key":"36","doi-asserted-by":"crossref","unstructured":"36. Shiozawa, E., Takimoto, M., Makino, R., Adachi, D., Saito, B., Yamochi-Onizuka, T., Yamochi, T., Shimozuma, J., Maeda, T., Kohno, Y., Kawakami, K., Nakamaki, T., Tomoyasu, S., Shiokawa, A. and Ota, H. 2006. Hypermethylation of CpG islands in p16 as a prognostic factor for diffuse large B-cell lymphoma in a high-risk group. Leuk. Res. 30: 859&ndash;867.","DOI":"10.1016\/j.leukres.2005.11.004"},{"key":"37","doi-asserted-by":"crossref","unstructured":"37. Starrak, G. S., Berry, C. R., Page, R. L., Johnson, J. L. and Thrall, D. E. 1997. Correlation between thoracic radiographic changes and remission\/survival duration in 270 dogs with lymphosarcoma. Vet. Radiol. Ultrasound 38: 411&ndash;418.","DOI":"10.1111\/j.1740-8261.1997.tb00863.x"},{"key":"38","doi-asserted-by":"crossref","unstructured":"38. Takasaki, Y., Yamada, Y., Sugahara, K., Hayashi, T., Dateki, N., Harasawa, H., Kawabata, S., Soda, H., Ikeda, S., Tomonaga, M. and Kamihira, S. 2003. Interruption of p16 gene expression in adult T-cell leukaemia\/lymphoma: clinical correlation. Br. J. Haematol. 122: 253&ndash;259.","DOI":"10.1046\/j.1365-2141.2003.04377.x"},{"key":"39","doi-asserted-by":"crossref","unstructured":"39. Taniguchi, T., Chikatsu, N., Takahashi, S., Fujita, A., Uchimaru, K., Asano, S., Fujita, T. and Motokura, T. 1999. Expression of p16INK4A and p14ARF in hematological malignancies. Leukemia 13: 1760&ndash;1769.","DOI":"10.1038\/sj.leu.2401557"},{"key":"40","doi-asserted-by":"crossref","unstructured":"40. Thomas, R., Seiser, E. L., Motsinger-Reif, A., Borst, L., Valli, V. E., Kelley, K., Suter, S. E., Argyle, D., Burgess, K., Bell, J., Lindblad-Toh, K., Modiano, J. F. and Breen, M. 2011. Refining tumor-associated aneuploidy through &lsquo;genomic recoding&rsquo; of recurrent DNA copy number aberrations in 150 canine non-Hodgkin lymphomas. Leuk. Lymphoma 52: 1321&ndash;1335.","DOI":"10.3109\/10428194.2011.559802"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1354\/vp.43-3-241"},{"key":"42","doi-asserted-by":"crossref","unstructured":"42. Wong, I. H., Ng, M. H., Huang, D. P. and Lee, J. C. 2000. Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: potential prognostic implications. 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