{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:01:32Z","timestamp":1759939292561},"reference-count":38,"publisher":"Japanese Society of Veterinary Science","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1292\/jvms.13-0036","type":"journal-article","created":{"date-parts":[[2013,3,7]],"date-time":"2013-03-07T02:39:31Z","timestamp":1362623971000},"page":"939-947","source":"Crossref","is-referenced-by-count":5,"title":["Histoplanimetrical Study on the Relationship between Invasion of Indigenous Bacteria into Intestinal Crypts and Proliferation of Epithelial Cells in Rat Ascending Colon"],"prefix":"10.1292","volume":"75","author":[{"given":"Youhei","family":"MANTANI","sequence":"first","affiliation":[{"name":"Laboratory of Histophysiology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ei-ichirou","family":"TAKAHARA","sequence":"additional","affiliation":[{"name":"Laboratory of Histophysiology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"TAKEUCHI","sequence":"additional","affiliation":[{"name":"Department of Veterinary Laboratory Animal Science, Faculty of Agriculture, Tottori University, 4\u2013101 Koyama-cho Minami, Tottori, Tottori 680\u20138553, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"KAWANO","sequence":"additional","affiliation":[{"name":"Laboratory of Microbiology and Immunology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshifumi","family":"YOKOYAMA","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Functional Morphology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiko","family":"HOSHI","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Functional Morphology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"KITAGAWA","sequence":"additional","affiliation":[{"name":"Laboratory of Histophysiology, Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University, 1\u20131 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657\u20138501, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.02.015"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3109\/00365529409096836"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Barthel, L. K. and Raymond, P. A. 1990. Improved method for obtaining 3-&mu;m cryosections for immunocytochemistry. J. Histochem. Cytochem. 38: 1383&ndash;1388.","DOI":"10.1177\/38.9.2201738"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Batt, R. M., Rutgers, H. C. and Sancak, A. A. 1996. Enteric bacteria: friend or foe?J. Small Anim. Pract. 37: 261&ndash;267.","DOI":"10.1111\/j.1748-5827.1996.tb02376.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Cario, E., Rosenberg, I. M., Brandwein, S. L., Beck, P. L., Reinecker, H.C. and Podolsky, D. K. 2000. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J. Immunol. 164: 966&ndash;972.","DOI":"10.4049\/jimmunol.164.2.966"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Cario, E., Brown, D., McKee, M., Lynch-Devaney, K., Gerken, G. and Podolsky, D. K. 2002. Commensal-associated molecular patterns induce selective Toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium. Am. J. Pathol. 160: 165&ndash;173.","DOI":"10.1016\/S0002-9440(10)64360-X"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Cole, A. M. and Ganz, T. 2005. Defensins and other antimicrobial peptides: innate defense of mucosal surfaces. pp. 17&ndash;34. <i>In<\/i>: Colonization of Mucosal Surfaces, 2nd ed. (James, P. N. <i>et al.<\/i> eds.), ASM Press, Washington, D. C.","DOI":"10.1128\/9781555817619.ch2"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1840"},{"key":"9","unstructured":"9. Enss, M.L., Grosse-Siestrup, H., Schmidt-Wittig, U. and G&auml;rtner, K. 1992. Changes in colonic mucins of germfree rats in response to the introduction of a &ldquo;normal&rdquo; rat microbial flora. J. Exp. Anim. Sci. 35: 110&ndash;119."},{"key":"10","unstructured":"10. Enss, M.L., Schmidt-Wittig, U., M&uuml;ller, H., Mai, U. E. H., Coenen, M. and Hedrich, H. J. 1996. Response of germfree rat colonic mucous cells to peroral endotoxin application. Eur. J. Cell Biol. 71: 99&ndash;104."},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/bies.200900192"},{"key":"12","unstructured":"12. Gleeson, M., McFarlin, B. and Flynn, M. 2006. Exercise and Toll-like receptors. Exerc. Immunol. Rev. 12: 34&ndash;53."},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.56.83"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.70.235"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.70.1153"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kim, M., Ashida, H., Ogawa, M., Yoshikawa, Y., Mimuro, H. and Sasakawa, C. 2010. Bacterial interactions with the host epithelium. Cell Host. Microbe 8: 20&ndash;35.","DOI":"10.1016\/j.chom.2010.06.006"},{"key":"17","unstructured":"17. Laubitz, D., Zabielski, R., Wolinski, J., Nieminuszczy, J. and Grzesiuk, E. 2003. Physiological and chemical characteristics of antibacterial activity of pancreatic juice. J. Physiol. Pharmacol. 54: 283&ndash;290."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Laux, D. C., Cohen, P. S. and Conway, T. 2005. Role of the mucus layer in bacterial colonization of the intestine. pp. 199&ndash;212. <i>In<\/i>: Colonization of Mucosal Surfaces, 2nd ed. (James, P. N. <i>et al.<\/i> eds.), ASM Press, Washington, D. C.","DOI":"10.1128\/9781555817619.ch15"},{"key":"19","unstructured":"19. Mantani, Y., Kamezaki, A., Udayanga, K. G. S., Takahara, E., Qi, W.M., Kawano, J., Yokoyama, T., Hoshi, N. and Kitagawa, H. 2011. Site differences of Toll-like receptor expression in the mucous epithelium of rat small intestine. Histol. Histopathol. 26: 1295&ndash;1303."},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.12-0146"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2538"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. McKernan, D. P., Nolan, A., Brint, E. K., O&rsquo;mahony, S. M., Hyland, N. P., Cryan, J. F. and Dinan, T. G. 2009. Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome. PLoS One 4: e8226.","DOI":"10.1371\/journal.pone.0008226"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001060305"},{"key":"24","unstructured":"24. Netea, M. G., Van der Meer, J. W. M. and Kullberg, B. J. 2006. Recognition of pathogenic microorganisms by Toll-like receptors. Drugs Today 42: 99&ndash;105."},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.01.007"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.463"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.745"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Salminen, S., Isolauri, E. and Onnela, T. 1995. Gut flora in normal and disordered states. Chemotherapy 41: 5&ndash;15.","DOI":"10.1159\/000239391"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(82)80075-0"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.58.205"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Sunter, J. P., Watson, A. J., Wright, N. A. and Appleton, D. R. 1979. Cell proliferation at different sites along the length of the rat colon. <i>Virchows Arch<\/i>. B Cell Path. 32: 75&ndash;87.","DOI":"10.1007\/BF02889015"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1007\/s00248-010-9737-z"},{"key":"33","doi-asserted-by":"crossref","unstructured":"33. Wang, Y., Devkota, S., Musch, M. W., Jabri, B., Nagler, C., Antonopoulos, D. A., Chervonsky, A. and Chang, E. B. 2010. Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon. PLoS One 5: e13607.","DOI":"10.1371\/journal.pone.0013607"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.71.621"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.10-0011"},{"key":"36","unstructured":"36. Yamada, K., Yoshitake, K., Sato, M. and Ahnen, D. J. 1992. Proliferating cell nuclear antigen expression in normal, preneoplastic, and neoplastic colonic epithelium of the rat. Gastroenterology 103: 160&ndash;167."},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.10-0293"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.11-0114"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/7\/75_13-0036\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T01:11:34Z","timestamp":1617066694000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/7\/75_13-0036\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":38,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.13-0036","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}