{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:20:44Z","timestamp":1783981244150,"version":"3.55.0"},"reference-count":22,"publisher":"Japanese Society of Veterinary Science","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2013]]},"DOI":"10.1292\/jvms.13-0127","type":"journal-article","created":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T23:02:11Z","timestamp":1371164531000},"page":"1355-1361","source":"Crossref","is-referenced-by-count":9,"title":["Adeno-Associated Viruses Serotype 2-Mediated RNA Interference Efficiently Inhibits Rabies Virus Replication <i>In Vitro<\/i> and <i>In Vivo<\/i>"],"prefix":"10.1292","volume":"75","author":[{"given":"Hong-Xia","family":"WU","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou 510642, P. R. China"},{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Lei","family":"WANG","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Feng","family":"GUO","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, South China Agricultural University, 483 Wushan Road, Guangzhou 510642, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Jiao","family":"YANG","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Zhu","family":"MA","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie-Cheng","family":"WANG","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Wei","family":"GAO","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Kun","family":"ZHAO","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song-Tao","family":"YANG","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian-Zhu","family":"XIA","sequence":"additional","affiliation":[{"name":"Military Veterinary Institute, Academy of Military Medical Sciences, 666 Liuyin Road, Changchun 130122, Jilin Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Afione, S. A., Conrad, C. K., Kearns, W. G., Chunduru, S., Adams, R., Reynolds, T. C., Guggino, W. B., Cutting, G. R., Carter, B. J. and Flotte, T. R. 1996. In vivo<\/i> model of adeno-associated virus vector persistence and rescue. J. Virol. 70: 3235–3241.","DOI":"10.1128\/JVI.70.5.3235-3241.1996"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Brandao, P. E., Castilho, J. G., Fahl, W., Carnieli, P. J., Oliveira, R. N., Macedo, C. I., Carrieri, M. L. and Kotait, I. 2007. Short-interfering RNAs as antivirals against rabies. Braz. J. Infect. Dis. 11: 224–225.","DOI":"10.1590\/S1413-86702007000200011"},{"key":"3","unstructured":"3. Burger, C., Gorbatyuk, O. S., Velardo, M. J., Peden, C. S., Williams, P., Zolotukhin, S., Reier, P. J., Mandel, R. J. and Muzyczka, N. 2004. Recombinant AAV viral vectors pseudotyped with viral capsids from 4. serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Mol. Ther. 10: 302–317."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Daya, S. and Berns, K. I. 2008. Gene therapy using adeno-associated virus vectors. Clin. Microbiol. Rev. 21: 583–593.","DOI":"10.1128\/CMR.00008-08"},{"key":"5","unstructured":"5. Fischer, A., Hacein-Bey-Abina, S., Lagresle, C., Garrigue, A. and Cavazana-Calvo, M. 2005. [Gene therapy of severe combined immunodeficiency disease: proof of principle of efficiency and safety issues. Gene therapy, primary immunodeficiencies, retrovirus, lentivirus, genome]. Bull. Acad. Natl. Med. 189: 779–785 (in French)."},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Fisher, K. J., Jooss, K., Alston, J., Yang, Y., Haecker, S. E., High, K., Pathak, R., Raper, S. E. and Wilson, J. M. 1997. Recombinant adeno-associated virus for muscle directed gene therapy. Nat. Med. 3: 306–312.","DOI":"10.1038\/nm0397-306"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Gupta, P. K., Sonwane, A. A., Singh, N. K., Meshram, C. D., Dahiya, S. S., Pawar, S. S., Gupta, S. P., Chaturvedi, V. K. and Saini, M. 2012. Intracerebral delivery of small interfering RNAs (siRNAs) using adenoviral vector protects mice against lethal peripheral rabies challenge. Virus Res. 163: 11–18.","DOI":"10.1016\/j.virusres.2011.08.004"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Israsena, N., Supavonwong, P., Ratanasetyuth, N., Khawplod, P. and Hemachudha, T. 2009. Inhibition of rabies virus replication by multiple artificial microRNAs. Antiviral Res. 84: 76–83.","DOI":"10.1016\/j.antiviral.2009.07.012"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Jackson, A. C. 2006. Rabies: new insights into pathogenesis and treatment. Curr. Opin. Neurol. 19: 267–270.","DOI":"10.1097\/01.wco.0000227036.93199.3b"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kumar, P., Ban, H. S., Kim, S. S., Wu, H., Pearson, T., Greiner, D. L., Laouar, A., Yao, J., Haridas, V., Habiro, K., Yang, Y. G., Jeong, J. H., Lee, K. Y., Kim, Y. H., Kim, S. W., Peipp, M., Fey, G. H., Manjunath, N., Shultz, L. D., Lee, S. K. and Shankar, P. 2008. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell 134: 577–586.","DOI":"10.1016\/j.cell.2008.06.034"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Li, B. J., Tang, Q., Cheng, D., Qin, C., Xie, F. Y., Wei, Q., Xu, J., Liu, Y., Zheng, B. J., Woodle, M. C., Zhong, N. and Lu, P. Y. 2005. Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat. Med. 11: 944–951.","DOI":"10.1038\/nm1280"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Mease, P. J., Hobbs, K., Chalmers, A., El-Gabalawy, H., Bookman, A., Keystone, E., Furst, D. E., Anklesaria, P. and Heald, A. E. 2009. Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study. Ann. Rheum. Dis. 68: 1247–1254.","DOI":"10.1136\/ard.2008.089375"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Morrissey, D. V., Lockridge, J. A., Shaw, L., Blanchard, K., Jensen, K., Breen, W., Hartsough, K., Machemer, L., Radka, S., Jadhav, V., Vaish, N., Zinnen, S., Vargeese, C., Bowman, K., Shaffer, C. S., Jeffs, L. B., Judge, A., MacLachlan, I. and Polisky, B. 2005. Potent and persistent in vivo<\/i> anti-HBV activity of chemically modified siRNAs. Nat. Biotechnol. 23: 1002–1007.","DOI":"10.1038\/nbt1122"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Padwad, Y. S., Mishra, K. P., Jain, M., Chanda, S., Karan, D. and Ganju, L. 2009. RNA interference mediated silencing of Hsp60 gene in human monocytic myeloma cell line U937 revealed decreased dengue virus multiplication. Immunobiology 214: 422–429.","DOI":"10.1016\/j.imbio.2008.11.010"},{"key":"15","unstructured":"15. Pandiri, A. R., Reed, W. M., Mays, J. K. and Fadly, A. M. 2007. Influence of strain, dose of virus, and age at inoculation on subgroup J avian leukosis virus persistence, antibody response, and oncogenicity in commercial meat-type chickens. Avian Dis. 51: 725–732."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Song, E., Lee, S. K., Wang, J., Ince, N., Ouyang, N., Min, J., Chen, J., Shankar, P. and Lieberman, J. 2003. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9: 347–351.","DOI":"10.1038\/nm828"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Sonwane, A. A., Dahiya, S. S., Saini, M., Chaturvedi, V. K., Singh, R. P. and Gupta, P. K. 2012. Inhibition of rabies virus multiplication by siRNA delivered through adenoviral vector in vitro<\/i> in BHK-21 cells and in vivo<\/i> in mice. Res. Vet. Sci. 93: 498–503.","DOI":"10.1016\/j.rvsc.2011.06.008"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Urabe, M., Ding, C. and Kotin, R. M. 2002. Insect cells as a factory to produce adeno-associated virus type 2 vectors. Hum. Gene Ther. 13: 1935–1943.","DOI":"10.1089\/10430340260355347"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Willoughby, R. E. Jr., Tieves, K. S., Hoffman, G. M., Ghanayem, N. S., Amlie-Lefond, C. M., Schwabe, M. J., Chusid, M. J. and Rupprecht, C. E. 2005. Survival after treatment of rabies with induction of coma. N. Engl. J. Med. 352: 2508–2514.","DOI":"10.1056\/NEJMoa050382"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Yang, Y. J., Zhao, P. S., Zhang, T., Wang, H. L., Liang, H. R., Zhao, L. L., Wu, H. X., Wang, T. C., Yang, S. T. and Xia, X. Z. 2012. Small interfering RNAs targeting the rabies virus nucleoprotein gene. Virus Res. 169: 169–174.","DOI":"10.1016\/j.virusres.2012.07.024"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Zhang, W., Wang, C. Y., Yang, S. T., Qin, C., Hu, J. L. and Xia, X. Z. 2009. Inhibition of highly pathogenic avian influenza virus H5N1 replication by the small interfering RNA targeting polymerase A gene. Biochem. Biophys. Res. Commun. 390: 421–426.","DOI":"10.1016\/j.bbrc.2009.09.039"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Zhang, Y., Chirmule, N., Gao, G. and Wilson, J. 2000. CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo<\/i>: role of immature dendritic cells. J. Virol. 74: 8003–8010.","DOI":"10.1128\/JVI.74.17.8003-8010.2000"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/10\/75_13-0127\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T01:12:04Z","timestamp":1617066724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/75\/10\/75_13-0127\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":22,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.13-0127","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}