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Albers, J. W., Herman, W. H., Pop-Busui, R., Feldman, E. L., Martin, C. L., Cleary, P. A., Waberski, B. H. and Lachin, J. M. 2010. Effect of prior intensive insulin treatment during the Diabetes Control and Complications Trial (DCCT) on peripheral neuropathy in type 1 diabetes during the Epidemiology of Diabetes Interventions and Complications (EDIC) Study. Diabetes Care 33: 1090&ndash;1096.","DOI":"10.2337\/dc09-1941"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Biessels, G. J., Stevens, E. J., Mahmood, S. J., Gispen, W. H. and Tomlinson, D. R. 1996. Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes. J. Neurol. Sci. 140: 12&ndash;20.","DOI":"10.1016\/0022-510X(96)00080-9"},{"key":"3","unstructured":"3. Britland, S. and Sharma, A. 1990. A comparison of the effects of conventional insulin treatment and continuous insulin infusion therapy on established morphological and biochemical abnormalities of peripheral nerve in experimental diabetes. Diabetes Res. 15: 143&ndash;150."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Britland, S. T., Young, R. J., Sharma, A. K. and Clarke, B. F. 1990. Relationship of endoneurial capillary abnormalities to type and severity of diabetic polyneuropathy. Diabetes 39: 909&ndash;913.","DOI":"10.2337\/diabetes.39.8.909"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Brussee, V., Cunningham, F. A. and Zochodne, D. W. 2004. Direct insulin signaling of neurons reverses diabetic neuropathy. Diabetes 53: 1824&ndash;1830.","DOI":"10.2337\/diabetes.53.7.1824"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Giannini, C. and Dyck, P. J. 1995. Basement membrane reduplication and pericyte degeneration precede development of diabetic polyneuropathy and are associated with its severity. Ann. Neurol. 37: 498&ndash;504.","DOI":"10.1002\/ana.410370412"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Hoybergs, Y. M. and Meert, T. F. 2007. The effect of low-dose insulin on mechanical sensitivity and allodynia in type I diabetes neuropathy. Neurosci. Lett. 417: 149&ndash;154.","DOI":"10.1016\/j.neulet.2007.02.087"},{"key":"8","unstructured":"8. Low, P. A. 2005. Pathogenesis of diabetic neuropathy. pp. 839&ndash;851. <i>In:<\/i> Joslin&rsquo;s Diabetes Mellitus (Kahn, C. R., <i>et al.<\/i> eds.), Lippincott Williams & Wilkins, Boston."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Malik, R. A., Newrick, P. G., Sharma, A. K., Jennings, A., Ah-See, A. K., Mayhew, T. M., Jakubowski, J., Boulton, A. J. and Ward, J. D. 1989. Microangiopathy in human diabetic neuropathy: relationship between capillary abnormalities and the severity of neuropathy. Diabetologia 32: 92&ndash;102.","DOI":"10.1007\/BF00505180"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Martin, C. L., Albers, J., Herman, W. H., Cleary, P., Waberski, B., Greene, D. A., Stevens, M. J. and Feldman, E. L. 2006. Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion. Diabetes Care 29: 340&ndash;344.","DOI":"10.2337\/diacare.29.02.06.dc05-1549"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. McCallum, K. N., Sharma, A. K., Blanchard, D. S., Stribling, D., Mirrlees, D. J., Duguid, I. G. and Thomas, P. K. 1986. The effect of continuous subcutaneous insulin infusion therapy on morphological and biochemical abnormalities of peripheral nerves in experimental diabetes. J. Neurol. Sci. 74: 55&ndash;67.","DOI":"10.1016\/0022-510X(86)90191-7"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Mohseni, S. and Hildebrand, C. 1998. Neuropathy in diabetic BB\/Wor rats treated with insulin implants. Acta Neuropathol. (Berl) 96: 144&ndash;150.","DOI":"10.1007\/s004010050874"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Nakama, K., Shichinohe, K., Kobayashi, K., Naito, K., Uchida, O., Yasuhara, K. and Tobe, M. 1985. Spontaneous diabetes-like syndrome in WBN\/KOB rats. Acta Diabetol. Lat. 22: 335&ndash;342.","DOI":"10.1007\/BF02624752"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Narama, I. and Kino, I. 1989. Peripheral motor neuropathy in spontaneously diabetic WBN\/Kob rats: a morphometric and electron microscopic study. Acta Neuropathol. (Berl.) 79: 52&ndash;60.","DOI":"10.1007\/BF00308958"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Ogawa, K., Sasaki, H., Yamasaki, H., Okamoto, K., Matsuno, S., Shono, T., Doi, T., Arimoto, K., Furuta, H., Nishi, M., Nakao, T. and Nanjo, K. 2006. Peripheral nerve functions may deteriorate parallel to the progression of microangiopathy in diabetic patients. Nutr. Metab. Cardiovasc. Dis. 16: 313&ndash;321.","DOI":"10.1016\/j.numecd.2005.06.003"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Ozaki, K., Miura, K., Tsuchitani, M. and Narama, I. 1996. Peripheral neuropathy in the spontaneously diabetic WBN\/Kob rat. Acta Neuropathol. (Berl.) 92: 603&ndash;607.","DOI":"10.1007\/s004010050567"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Pierson, C. R., Zhang, W., Murakawa, Y. and Sima, A. A. 2003. Insulin deficiency rather than hyperglycemia accounts for impaired neurotrophic responses and nerve fiber regeneration in type 1 diabetic neuropathy. J. Neuropathol. Exp. Neurol. 62: 260&ndash;271.","DOI":"10.1093\/jnen\/62.3.260"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Sugimoto, K., Baba, M., Suda, T., Yasujima, M. and Yagihashi, S. 2003. Peripheral neuropathy and microangiopathy in rats with insulinoma: association with chronic hyperinsulinemia. Diabetes Metab. Res. Rev. 19: 392&ndash;400.","DOI":"10.1002\/dmrr.395"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Sugimoto, K., Murakawa, Y., Zhang, W., Xu, G. and Sima, A. A. 2000. Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms. Diabetes Metab. Res. Rev. 16: 354&ndash;363.","DOI":"10.1002\/1520-7560(200009\/10)16:5<354::AID-DMRR149>3.0.CO;2-H"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Tsuchitani, M., Saegusa, T., Narama, I., Nishikawa, T. and Gonda, T. 1985. A new diabetic strain of rat (WBN\/Kob). Lab. Anim. 19: 200&ndash;207.","DOI":"10.1258\/002367785780893575"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. van Dam, P. S., Bravenboer, B., van Asbeck, B. S., van Oirschot, J. F., Marx, J. J. and Gispen, W. H. 1996. Effects of insulin treatment on endoneurial and systemic oxidative stress in relation to nerve conduction in streptozotocin-diabetic rats. Eur. J. Clin. Invest. 26: 1143&ndash;1149.","DOI":"10.1046\/j.1365-2362.1996.510601.x"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Westfall, S. G., Felten, D. L., Mandelbaum, J. A., Moore, S. A. and Peterson, R. G. 1983. Degenerative neuropathy in insulin-treated diabetic rats. J. Neurol. Sci. 61: 93&ndash;107.","DOI":"10.1016\/0022-510X(83)90057-6"},{"key":"23","unstructured":"23. Yagihashi, S., Kamijo, M. and Watanabe, K. 1990. Reduced myelinated fiber size correlates with loss of axonal neurofilaments in peripheral nerve of chronically streptozotocin diabetic rats. Am. J. Pathol. 136: 1365&ndash;1373."},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Yagihashi, S., Kudo, K. and Nishihira, M. 1979. Peripheral nerve structures of experimental diabetes rats and the effect of insulin treatment. Tohoku J. Exp. Med. 127: 35&ndash;44.","DOI":"10.1620\/tjem.127.35"},{"key":"25","unstructured":"25. Yagihashi, S., Wada, R., Kamijo, M. and Nagai, K. 1993. Peripheral neuropathy in the WBN\/Kob rat with chronic pancreatitis and spontaneous diabetes. Lab. 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