{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:43:44Z","timestamp":1770270224400,"version":"3.49.0"},"reference-count":20,"publisher":"Japanese Society of Veterinary Science","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Veterinary Medical Science","J. Vet. Med. Sci."],"published-print":{"date-parts":[[2014]]},"DOI":"10.1292\/jvms.14-0166","type":"journal-article","created":{"date-parts":[[2014,8,31]],"date-time":"2014-08-31T19:32:56Z","timestamp":1409513576000},"page":"1641-1645","source":"Crossref","is-referenced-by-count":6,"title":["Molecular Cloning and Gene Expression of Canine Apoptosis Inhibitor of Macrophage"],"prefix":"10.1292","volume":"76","author":[{"given":"Shintaro","family":"TOMURA","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Clinical Pathobiology, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1\u20131\u20131 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"UCHIDA","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Pathobiology, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1\u20131\u20131 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"YONEZAWA","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Pathobiology, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1\u20131\u20131 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masato","family":"KOBAYASHI","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, 1\u20137\u20131 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"BONKOBARA","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Pathology, Nippon Veterinary and Life Science University, 1\u20137\u20131 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoko","family":"ARAI","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, 7\u20133\u20131 Hongo Bunkyo-ku, Tokyo 113-0033, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"MIYAZAKI","sequence":"additional","affiliation":[{"name":"CREST, Japan Science and Technology Agency, Hongo Bunkyo-ku, Tokyo 113-0033, Japan"},{"name":"Laboratory of Molecular Biomedicine for Pathogenesis, Center for Disease Biology and Integrative Medicine, Faculty of Medicine, The University of Tokyo, 7\u20133\u20131 Hongo Bunkyo-ku, Tokyo 113-0033, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"TAMAHARA","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Pathobiology, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1\u20131\u20131 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoaki","family":"MATSUKI","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Clinical Pathobiology, Department of Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1\u20131\u20131 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Affolter, V. K. and Moore, P. F. 2002. Localized and disseminated histiocytic sarcoma of dendritic cell origin in dogs. <i>Vet. Pathol.<\/i> 39: 74\u201383.","DOI":"10.1354\/vp.39-1-74"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Arai, S., Shelton, J. M., Chen, M., Bradley, M. N., Castrillo, A., Bookout, A. L., Mak, P. A., Edwards, P. A., Mangelsdorf, D. J., Tontonoz, P. and Miyazaki, T. 2005. A role for the apoptosis inhibitory factor AIM\/Spalpha\/Api6 in atherosclerosis development. <i>Cell Metab.<\/i> 1: 201\u2013213.","DOI":"10.1016\/j.cmet.2005.02.002"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Azakami, D., Bonkobara, M., Washizu, T., Iida, A., Kondo, M., Kato, R., Niikura, Y., Iwaki, S., Tamahara, S., Matsuki, N. and Ono, K. 2006. Establishment and biological characterization of canine histiocytic sarcoma cell lines. <i>J. Vet. Med. Sci.<\/i> 68: 1343\u20131346.","DOI":"10.1292\/jvms.68.1343"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Febbraio, M., Podrez, E. A., Smith, J. D., Hajjar, D. P., Hazen, S. L., Hoff, H. F., Sharma, K. and Silverstein, R. L. 2000. Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. <i>J. Clin. Invest.<\/i> 105: 1049\u20131056.","DOI":"10.1172\/JCI9259"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Freeman, M., Ashkenas, J., Rees, D. J., Kingsley, D. M., Copeland, N. G., Jenkins, N. A. and Krieger, M. 1990. An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> 87: 8810\u20138814.","DOI":"10.1073\/pnas.87.22.8810"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Gangadharan, B., Antrobus, R., Dwek, R. A. and Zitzmann, N. 2007. Novel serum biomarker candidates for liver fibrosis in hepatitis C patients. <i>Clin. Chem.<\/i> 53: 1792\u20131799.","DOI":"10.1373\/clinchem.2007.089144"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Gebe, J. A., Kiener, P. A., Ring, H. Z., Li, X., Francke, U. and Aruffo, A. 1997. Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins. <i>J. Biol. Chem.<\/i> 272: 6151\u20136158.","DOI":"10.1074\/jbc.272.10.6151"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Gray, J., Chattopadhyay, D., Beale, G. S., Patman, G. L., Miele, L., King, B. P., Stewart, S., Hudson, M., Day, C. P., Manas, D. M. and Reeves, H. L. 2009. A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease. <i>BMC Cancer<\/i> 9: 271.","DOI":"10.1186\/1471-2407-9-271"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Kim, W. K., Hwang, H. R., Kim, H., Lee, P. Y., In, Y. J., Ryu, H. Y., Park, S. G., Bae, K. H. and Lee, S. C. 2008. Glycoproteomic analysis of plasma from patients with atopic dermatitis: CD5L and ApoE as potential biomarkers. <i>Exp. Mol. Med.<\/i> 40: 677\u2013685.","DOI":"10.3858\/emm.2008.40.6.677"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Krieger, M. 1992. Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor. <i>Trends Biochem. Sci.<\/i> 17: 141\u2013146.","DOI":"10.1016\/0968-0004(92)90322-Z"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kurokawa, J., Arai, S., Nakashima, K., Nagano, H., Nishijima, A., Miyata, K., Ose, R., Mori, M., Kubota, N., Kadowaki, T., Oike, Y., Koga, H., Febbraio, M., Iwanaga, T. and Miyazaki, T. 2010. Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity. <i>Cell Metab.<\/i> 11: 479\u2013492.","DOI":"10.1016\/j.cmet.2010.04.013"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Kurokawa, J., Nagano, H., Ohara, O., Kubota, N., Kadowaki, T., Arai, S. and Miyazaki, T. 2011. Apoptosis inhibitor of macrophage (AIM) is required for obesity-associated recruitment of inflammatory macrophages into adipose tissue. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> 108: 12072\u201312077.","DOI":"10.1073\/pnas.1101841108"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Kuwata, K., Watanabe, H., Jiang, S. Y., Yamamoto, T., Tomiyama-Miyaji, C., Abo, T., Miyazaki, T. and Naito, M. 2003. AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. <i>Am. J. Pathol.<\/i> 162: 837\u2013847.","DOI":"10.1016\/S0002-9440(10)63880-1"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Miyazaki, T., Hirokami, Y., Matsuhashi, N., Takatsuka, H. and Naito, M. 1999. Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. <i>J. Exp. Med.<\/i> 189: 413\u2013422.","DOI":"10.1084\/jem.189.2.413"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Moore, P. F., Affolter, V. K. and Vernau, W. 2006. Canine hemophagocytic histiocytic sarcoma: a proliferative disorder of CD11d+ macrophages. <i>Vet. Pathol.<\/i> 43: 632\u2013645.","DOI":"10.1354\/vp.43-5-632"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Neels, J. G. and Olefsky, J. M. 2006. Inflamed fat: what starts the fire? <i>J. Clin. Invest.<\/i> 116: 33\u201335.","DOI":"10.1172\/JCI27280"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Resnick, D., Chatterton, J. E., Schwartz, K., Slayter, H. and Krieger, M. 1996. Structures of class A macrophage scavenger receptors. Electron microscopic study of flexible, multidomain, fibrous proteins and determination of the disulfide bond pattern of the scavenger receptor cysteine-rich domain. <i>J. Biol. Chem.<\/i> 271: 26924\u201326930.","DOI":"10.1074\/jbc.271.43.26924"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Resnick, D., Pearson, A. and Krieger, M. 1994. The SRCR superfamily: a family reminiscent of the Ig superfamily. <i>Trends Biochem. Sci.<\/i> 19: 5\u20138.","DOI":"10.1016\/0968-0004(94)90165-1"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Shoelson, S. E., Lee, J. and Goldfine, A. B. 2006. Inflammation and insulin resistance. <i>J. Clin. Invest.<\/i> 116: 1793\u20131801.","DOI":"10.1172\/JCI29069"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Yusa, S., Ohnishi, S., Onodera, T. and Miyazaki, T. 1999. AIM, a murine apoptosis inhibitory factor, induces strong and sustained growth inhibition of B lymphocytes in combination with TGF-beta1. <i>Eur. J. Immunol.<\/i> 29: 1086\u20131093.","DOI":"10.1002\/(SICI)1521-4141(199904)29:04<1086::AID-IMMU1086>3.0.CO;2-X"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T15:39:28Z","timestamp":1498145968000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/76\/12\/76_14-0166\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":20,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.14-0166","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}