{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:38:03Z","timestamp":1790267883300,"version":"4.1.0"},"reference-count":28,"publisher":"Japanese Society of Veterinary Science","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Veterinary Medical Science","J. Vet. Med. Sci."],"published-print":{"date-parts":[[2014]]},"DOI":"10.1292\/jvms.14-0258","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T01:59:25Z","timestamp":1410919165000},"page":"1555-1561","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of Surgical Methods of Transient Middle Cerebral Artery Occlusion between Rats and Mice"],"prefix":"10.1292","volume":"76","author":[{"given":"Seunghoon","family":"LEE","sequence":"first","affiliation":[{"name":"Biohealth Products Research Center (BPRC), Inje University, Gimhae, Korea"},{"name":"Ubiquitous Healthcare &amp; Anti-aging Research Center (u-HARC), Inje University, Gimhae, Korea"},{"name":"Department of Physical Therapy, College of Biomedical Science &amp; Engineering, Inje University, Gimhae, Korea"},{"name":"Department of Rehabilitation Science, Graduate School of Inje University, Gimhae, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunkyung","family":"HONG","sequence":"additional","affiliation":[{"name":"Biohealth Products Research Center (BPRC), Inje University, Gimhae, Korea"},{"name":"Ubiquitous Healthcare &amp; Anti-aging Research Center (u-HARC), Inje University, Gimhae, Korea"},{"name":"Department of Physical Therapy, College of Biomedical Science &amp; Engineering, Inje University, Gimhae, Korea"},{"name":"Department of Rehabilitation Science, Graduate School of Inje University, Gimhae, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sookyoung","family":"PARK","sequence":"additional","affiliation":[{"name":"Ubiquitous Healthcare &amp; Anti-aging Research Center (u-HARC), Inje University, Gimhae, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Rae","family":"LEE","sequence":"additional","affiliation":[{"name":"National Primate Research Center (NPRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-Tae","family":"CHANG","sequence":"additional","affiliation":[{"name":"National Primate Research Center (NPRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Ochang, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonggeun","family":"HONG","sequence":"additional","affiliation":[{"name":"Biohealth Products Research Center (BPRC), Inje University, Gimhae, Korea"},{"name":"Ubiquitous Healthcare &amp; Anti-aging Research Center (u-HARC), Inje University, Gimhae, Korea"},{"name":"Department of Physical Therapy, College of Biomedical Science &amp; Engineering, Inje University, Gimhae, Korea"},{"name":"Department of Rehabilitation Science, Graduate School of Inje University, Gimhae, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Alonso de Leci\u00f1ana, M., D\u00edez-Tejedor, E., Carceller, F. and Roda, J. M. 2001. Cerebral ischemia: from animal studies to clinical practice. Should the methods be reviewed? <i>Cerebrovasc. Dis.<\/i> 11 Suppl 1: 20\u201330.","DOI":"10.1159\/000049122"},{"key":"2","unstructured":"2. Armstead, W. M., Ganguly, K., Kiessling, J. W., Riley, J., Chen, X. H., Smith, D. H., Stein, S. C., Higazi, A. A., Cines, D. B., Bdeir, K., Zaitsev, S. and Muzykantov, V. R. 2010. Signaling, delivery and age as emerging issues in the benefit\/risk ratio outcome of tPA For treatment of CNS ischemic disorders. <i>J. Neurochem.<\/i> 113: 303\u2013312."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Aspey, B. S., Taylor, F. L., Terruli, M. and Harrison, M. J. 2000. Temporary middle cerebral artery occlusion in the rat: consistent protocol for a model of stroke and reperfusion. <i>Neuropathol. Appl. Neurobiol.<\/i> 26: 232\u2013242.","DOI":"10.1046\/j.1365-2990.2000.00221.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Bederson, J. B., Pitts, L. H., Tsuji, M., Nishimura, M. C., Davis, R. L. and Bartkowski, H. 1986. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. <i>Stroke<\/i> 17: 472\u2013476.","DOI":"10.1161\/01.STR.17.3.472"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Blanpain, C. 2013. Tracing the cellular origin of cancer. <i>Nat. Cell Biol.<\/i> 15: 126\u2013134.","DOI":"10.1038\/ncb2657"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Chiang, T., Messing, R. O. and Chou, W. H. 2011. Mouse model of middle cerebral artery occlusion. <i>J. Vis. Exp.<\/i> 48: 2761.","DOI":"10.3791\/2761"},{"key":"7","unstructured":"7. Durukan, A. and Tatlisumak, T. 2007. Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. <i>Pharmacol. Biochem. Behav.<\/i> 87: 179\u2013197."},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Engel, O., Kolodziej, S., Dirnagl, U. and Prinz, V. 2011. Modeling stroke in mice - middle cerebral artery occlusion with the filament model. <i>J. Vis. Exp.<\/i> 47: 2423.","DOI":"10.3791\/2423"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Jung, J. E., Kim, G. S., Chen, H., Maier, C. M., Narasimhan, P., Song, Y. S., Niizuma, K., Katsu, M., Okami, N., Yoshioka, H., Sakata, H., Goeders, C. E. and Chan, P. H. 2010. Reperfusion and neurovascular dysfunction in stroke: from basic mechanisms to potential strategies for neuroprotection. <i>Mol. Neurobiol.<\/i> 41: 172\u2013179.","DOI":"10.1007\/s12035-010-8102-z"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Lee, S., Lee, M., Hong, Y., Won, J., Kang, S. G. and Hong, Y. 2014. Comparison of middle cerebral artery occlusion methods in rat pand mouse transient focal cerebral ischemic stroke models. <i>Neural Regen. Res.<\/i> 9: 757\u2013758.","DOI":"10.4103\/1673-5374.131582"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Lee, S., Shin, J., Hong, Y., Lee, M., Kim, K., Lee, S. R., Chang, K. T. and Hong, Y. 2012. Beneficial effects of melatonin on stroke-induced muscle atrophy in focal cerebral ischemic rats. <i>Lab. Anim. Res.<\/i> 28: 47\u201354.","DOI":"10.5625\/lar.2012.28.1.47"},{"key":"12","unstructured":"12. Lee, S., Shin, J., Lee, M., Hong, Y., Lee, S. K., Lee, Y., Lkhavasuren, T., Kim, D. W., Yang, Y. A., Chang, K. T. and Hong, Y. 2012. Melatonin combined with exercise cannot alleviate cerebral injury in a rat model of focal cerebral ischemia\/reperfusion injury. <i>Neural Regen. Res.<\/i> 7: 993\u2013999."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Liu, F. and McCullough, L. D. 2011. Middle cerebral artery occlusion model in rodents: methods and potential pitfalls. <i>J. Biomed. Biotechnol.<\/i> 2011: 464701.","DOI":"10.1155\/2011\/464701"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Longa, E. Z., Weinstein, P. R., Carlson, S. and Cummins, R. 1989. Reversible middle cerebral artery occlusion without craniectomy in rats. <i>Stroke<\/i> 20: 84\u201391.","DOI":"10.1161\/01.STR.20.1.84"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Maeda, K., Hata, R. and Hossmann, K. A. 1998. Differences in the cerebrovascular anatomy of C57black\/6 and SV129 mice. <i>Neuroreport<\/i> 9: 1317\u20131319.","DOI":"10.1097\/00001756-199805110-00012"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Maeda, K., Hata, R. and Hossmann, K. A. 1999. Regional metabolic disturbances and cerebrovascular anatomy after permanent middle cerebral artery occlusion in C57black\/6 and SV129 mice. <i>Neurobiol. Dis.<\/i> 6: 101\u2013108.","DOI":"10.1006\/nbdi.1998.0235"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Matute, C. 2011. Therapeutic potential of kainate receptors. <i>CNS Neurosci. Ther.<\/i> 17: 661\u2013669.","DOI":"10.1111\/j.1755-5949.2010.00204.x"},{"key":"18","unstructured":"18. Megyesi, J. F., Vollrath, B., Cook, D. A. and Findlay, J. M. 2000. <i>In vivo<\/i> animal models of cerebral vasospasm: a review. <i>Neurosurgery<\/i> 46: 448\u2013460, discussion 460\u2013461."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Ozdemir, Y. G., Bolay, H., Erdem, E. and Dalkara, T. 1999. Occlusion of the MCA by an intraluminal filament may cause disturbances in the hippocampal blood flow due to anomalies of circle of Willis and filament thickness. <i>Brain Res.<\/i> 822: 260\u2013264.","DOI":"10.1016\/S0006-8993(99)01175-0"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Park, S., Shin, J., Hong, Y., Kim, S., Lee, S., Park, K., Lkhagvasuren, T., Lee, S. R., Chang, K. T. and Hong, Y. 2012. Forced exercise enhances functional recovery after focal cerebral ischemia in spontaneously hypertensive rats. <i>Brain Sci.<\/i> 2: 483\u2013503.","DOI":"10.3390\/brainsci2040483"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Rodriguez, R., Santiago-Mejia, J., Gomez, C. and San-Juan, E. R. 2005. A simplified procedure for the quantitative measurement of neurological deficits after forebrain ischemia in mice. <i>J. Neurosci. Methods<\/i> 147: 22\u201328.","DOI":"10.1016\/j.jneumeth.2005.02.013"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Rosamond, W., Flegal, K., Furie, K., Go, A., Greenlund, K., Haase, N., Hailpern, S. M., Ho, M., Howard, V., Kissela, B., Kittner, S., Lloyd-Jones, D., McDermott, M., Meigs, J., Moy, C., Nichol, G., O\u2019Donnell, C., Roger, V., Sorlie, P., Steinberger, J., Thom, T., Wilson, M., Hong, Y., American Heart Association Statistics Committee and Stroke Statistics Subcommittee2008. Heart disease and stroke statistics\u20142008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. <i>Circulation<\/i> 117: e25\u2013e146.","DOI":"10.1161\/CIRCULATIONAHA.107.187998"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Rousselet, E., Kriz, J. and Seidah, N. G. 2012. Mouse model of intraluminal MCAO: cerebral infarct evaluation by cresyl violet staining. <i>J. Vis. Exp.<\/i> 69: 4038.","DOI":"10.3791\/4038"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Traystman, R. J. 2003. Animal models of focal and global cerebral ischemia. <i>ILAR J.<\/i> 44: 85\u201395.","DOI":"10.1093\/ilar.44.2.85"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Tsuchiya, D., Hong, S., Kayama, T., Panter, S. S. and Weinstein, P. R. 2003. Effect of suture size and carotid clip application upon blood flow and infarct volume after permanent and temporary middle cerebral artery occlusion in mice. <i>Brain Res.<\/i> 970: 131\u2013139.","DOI":"10.1016\/S0006-8993(03)02300-X"},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Verkman, A. S. 2009. Knock-out models reveal new aquaporin functions. <i>Handbook Exp. Pharmacol.<\/i> 190: 359\u2013381.","DOI":"10.1007\/978-3-540-79885-9_18"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Wexler, E. J., Peters, E. E., Gonzales, A., Gonzales, M. L., Slee, A. M. and Kerr, J. S. 2002. An objective procedure for ischemic area evaluation of the stroke intraluminal thread model in the mouse and rat. <i>J. Neurosci. Methods<\/i> 113: 51\u201358.","DOI":"10.1016\/S0165-0270(01)00476-9"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Yang, G., Kitagawa, K., Matsushita, K., Mabuchi, T., Yagita, Y., Yanagihara, T. and Matsumoto, M. 1997. C57BL\/6 strain is most susceptible to cerebral ischemia following bilateral common carotid occlusion among seven mouse strains: selective neuronal death in the murine transient forebrain ischemia. <i>Brain Res.<\/i> 752: 209\u2013218.","DOI":"10.1016\/S0006-8993(96)01453-9"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","deposited":{"date-parts":[[2019,8,15]],"date-time":"2019-08-15T02:45:40Z","timestamp":1565837140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/76\/12\/76_14-0258\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":28,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.14-0258","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}