{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T16:25:20Z","timestamp":1768580720305,"version":"3.49.0"},"reference-count":32,"publisher":"Japanese Society of Veterinary Science","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Veterinary Medical Science","J. Vet. Med. Sci."],"published-print":{"date-parts":[[2018]]},"DOI":"10.1292\/jvms.17-0569","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T22:20:36Z","timestamp":1512512436000},"page":"116-124","source":"Crossref","is-referenced-by-count":10,"title":["Annexin A1 is a novel target gene of gonadotropin-releasing hormone in L\u03b2T2 gonadotrope cells"],"prefix":"10.1292","volume":"80","author":[{"given":"Numfa","family":"FUNGBUN","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doungrut","family":"TUNGMAHASUK","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"TERASHIMA","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiro","family":"KURUSU","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsumori","family":"KAWAMINAMI","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Physiology, School of Veterinary Medicine, Kitasato University, Towada, Aomori 034-8628, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Buckingham, J. C. 1996. Fifteenth Gaddum Memorial Lecture December 1994. Stress and the neuroendocrine-immune axis: the pivotal role of glucocorticoids and lipocortin 1. <i>Br. J. Pharmacol.<\/i> 118: 1\u201319.","DOI":"10.1111\/j.1476-5381.1996.tb15360.x"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Buckingham, J. C. and Flower, R. J. 1997. Lipocortin 1: a second messenger of glucocorticoid action in the hypothalamo-pituitary-adrenocortical axis. <i>Mol. Med. Today<\/i> 3: 296\u2013302.","DOI":"10.1016\/S1357-4310(97)88908-3"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Cirino, G., Peers, S. H., Flower, R. J., Browning, J. L. and Pepinsky, R. B. 1989. Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> 86: 3428\u20133432.","DOI":"10.1073\/pnas.86.9.3428"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Crompton, M. R., Moss, S. E. and Crumpton, M. J. 1988. Diversity in the lipocortin\/calpactin family. <i>Cell<\/i> 55: 1\u20133.","DOI":"10.1016\/0092-8674(88)90002-5"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. De Loof, A., Lindemans, M., Liu, F., De Groef, B. and Schoofs, L. 2012. Endocrine archeology: do insects retain ancestrally inherited counterparts of the vertebrate releasing hormones GnRH, GHRH, TRH, and CRF? <i>Gen. Comp. Endocrinol.<\/i> 177: 18\u201327.","DOI":"10.1016\/j.ygcen.2012.02.002"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Flower, R. J. 1986. The mediators of steroid action. <i>Nature<\/i> 320: 20.","DOI":"10.1038\/320020a0"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Gerke, V. and Moss, S. E. 2002. Annexins: from structure to function. <i>Physiol. Rev.<\/i> 82: 331\u2013371.","DOI":"10.1152\/physrev.00030.2001"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Hannon, R., Croxtall, J. D., Getting, S. J., Roviezzo, F., Yona, S., Paul-Clark, M. J., Gavins, F. N., Perretti, M., Morris, J. F., Buckingham, J. C. and Flower, R. J. 2003. Aberrant inflammation and resistance to glucocorticoids in annexin 1-\/- mouse. <i>FASEB J.<\/i> 17: 253\u2013255.","DOI":"10.1096\/fj.02-0239fje"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Hoque, M., Rentero, C., Cairns, R., Tebar, F., Enrich, C. and Grewal, T. 2014. Annexins - scaffolds modulating PKC localization and signaling. <i>Cell. Signal.<\/i> 26: 1213\u20131225.","DOI":"10.1016\/j.cellsig.2014.02.012"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kakar, S. S. and Jennes, L. 1995. Expression of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor mRNAs in various non-reproductive human tissues. <i>Cancer Lett.<\/i> 98: 57\u201362.","DOI":"10.1016\/S0304-3835(06)80010-8"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Kakar, S. S., Winters, S. J., Zacharias, W., Miller, D. M. and Flynn, S. 2003. Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis. <i>Gene<\/i> 308: 67\u201377.","DOI":"10.1016\/S0378-1119(03)00446-3"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Kawaminami, M., Etoh, S., Miyaoka, H., Sakai, M., Nishida, M., Kurusu, S. and Hashimoto, I. 2002. Annexin 5 messenger ribonucleic acid expression in pituitary gonadotropes is induced by gonadotropin-releasing hormone (GnRH) and modulates GnRH stimulation of gonadotropin release. <i>Neuroendocrinology<\/i> 75: 2\u201311.","DOI":"10.1159\/000048216"},{"key":"13","unstructured":"13. Kawaminami, M., Kawamoto, T., Tanabe, T., Yamaguchi, K., Mutoh, K., Kurusu, S. and Hashimoto, I. 1998. Immunocytochemical localization of annexin 5, a calcium-dependent phospholipid-binding protein, in rat endocrine organs. <i>Cell Tissue Res.<\/i> 292: 85\u201389."},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Kawaminami, M., Shibata, Y., Yaji, A., Kurusu, S. and Hashimoto, I. 2003. Prolactin inhibits annexin 5 expression and apoptosis in the corpus luteum of pseudopregnant rats: involvement of local gonadotropin-releasing hormone. <i>Endocrinology<\/i> 144: 3625\u20133631.","DOI":"10.1210\/en.2003-0118"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Kawaminami, M., Tanaka, K., Asawa, T., Osugi, S., Kawauchi, H., Kurusu, S. and Hashimoto, I. 1992. Association of annexin V with prolactin in the rat anterior pituitary gland. <i>Biochem. Biophys. Res. Commun.<\/i> 186: 894\u2013898.","DOI":"10.1016\/0006-291X(92)90830-E"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Kawaminami, M., Tsuchiyama, Y., Saito, S., Katayama, M., Kurusu, S. and Hashimoto, I. 2002. Gonadotropin-releasing hormone stimulates annexin 5 messenger ribonucleic acid expression in the anterior pituitary cells. <i>Biochem. Biophys. Res. Commun.<\/i> 291: 915\u2013920.","DOI":"10.1006\/bbrc.2002.6573"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Kawaminami, M., Yamaguchi, K., Miyagawa, S., Numazawa, S., Ioka, H., Kurusu, S. and Hashimoto, I. 1998. Ovariectomy enhances the expression and nuclear translocation of annexin 5 in rat anterior pituitary gonadotrophs. <i>Mol. Cell. Endocrinol.<\/i> 141: 73\u201378.","DOI":"10.1016\/S0303-7207(98)00091-4"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Lin, X. W., Otto, C. J. and Peter, R. E. 1998. Evolution of neuroendocrine peptide systems: gonadotropin-releasing hormone and somatostatin. <i>Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol.<\/i> 119: 375\u2013388.","DOI":"10.1016\/S0742-8413(98)00025-5"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Morgan, K. and Millar, R. P. 2004. Evolution of GnRH ligand precursors and GnRH receptors in protochordate and vertebrate species. <i>Gen. Comp. Endocrinol.<\/i> 139: 191\u2013197.","DOI":"10.1016\/j.ygcen.2004.09.015"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Morgan, R. O. and Fern\u00e1ndez, M. P. 1997. Annexin gene structures and molecular evolutionary genetics. <i>Cell. Mol. Life Sci.<\/i> 53: 508\u2013515.","DOI":"10.1007\/s000180050064"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Neill, J. D. 2002. GnRH and GnRH receptor genes in the human genome. <i>Endocrinology<\/i> 143: 737\u2013743.","DOI":"10.1210\/en.143.3.737"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Powell, J. F., Reska-Skinner, S. M., Prakash, M. O., Fischer, W. H., Park, M., Rivier, J. E., Craig, A. G., Mackie, G. O. and Sherwood, N. M. 1996. Two new forms of gonadotropin-releasing hormone in a protochordate and the evolutionary implications. <i>Proc. Natl. Acad. Sci. U.S.A.<\/i> 93: 10461\u201310464.","DOI":"10.1073\/pnas.93.19.10461"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Raynal, P., Hullin, F., Ragab-Thomas, J. M., Fauvel, J. and Chap, H. 1993. Annexin 5 as a potential regulator of annexin 1 phosphorylation by protein kinase C. In vitro inhibition compared with quantitative data on annexin distribution in human endothelial cells. <i>Biochem. J.<\/i> 292: 759\u2013765.","DOI":"10.1042\/bj2920759"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Rieanrakwong, D., Laoharatchatathanin, T., Terashima, R., Yonezawa, T., Kurusu, S., Hasegawa, Y. and Kawaminami, M. 2016. Prolactin Suppression of Gonadotropin-Releasing Hormone Initiation of Mammary Gland Involution in Female Rats. <i>Endocrinology<\/i> 157: 2750\u20132758.","DOI":"10.1210\/en.2016-1180"},{"key":"25","unstructured":"25. Roviezzo, F., Getting, S. J., Paul-Clark, M. J., Yona, S., Gavins, F. N., Perretti, M., Hannon, R., Croxtall, J. D., Buckingham, J. C. and Flower, R. J. 2002. The annexin-1 knockout mouse: what it tells us about the inflammatory response. <i>J. Physiol. Pharmacol.<\/i> 53: 541\u2013553."},{"key":"26","doi-asserted-by":"crossref","unstructured":"26. Taylor, A. D., Flower, R. J. and Buckingham, J. C. 1995. Dexamethasone inhibits the release of TSH from the rat anterior pituitary gland in vitro by mechanisms dependent on de novo protein synthesis and lipocortin 1. <i>J. Endocrinol.<\/i> 147: 533\u2013544.","DOI":"10.1677\/joe.0.1470533"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Taylor, A. D., Cowell, A. M., Flower, J. and Buckingham, J. C. 1993. Lipocortin 1 mediates an early inhibitory action of glucocorticoids on the secretion of ACTH by the rat anterior pituitary gland in vitro. <i>Neuroendocrinology<\/i> 58: 430\u2013439.","DOI":"10.1159\/000126572"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Taylor, A. D., Cowell, A. M., Flower, R. J. and Buckingham, J. C. 1995. Dexamethasone suppresses the release of prolactin from the rat anterior pituitary gland by lipocortin 1 dependent and independent mechanisms. <i>Neuroendocrinology<\/i> 62: 530\u2013542.","DOI":"10.1159\/000127044"},{"key":"29","unstructured":"29. Taylor, A. D., Philip, J. G., John, C. D., Cover, P. O., Morris, J. F., Flower, R. J. and Buckingham, J. C. 2000. Annexin 1 (lipocortin 1) mediates the glucocorticoid inhibition of cyclic adenosine 3\u2032,5\u2032-monophosphate-stimulated prolactin secretion. <i>Endocrinology<\/i> 141: 2209\u20132219."},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Traverso, V., Christian, H. C., Morris, J. F. and Buckingham, J. C. 1999. Lipocortin 1 (annexin 1): a candidate paracrine agent localized in pituitary folliculo-stellate cells. <i>Endocrinology<\/i> 140: 4311\u20134319.","DOI":"10.1210\/en.140.9.4311"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Ueki, H., Mizushina, T., Laoharatchatathanin, T., Terashima, R., Nishimura, Y., Rieanrakwong, D., Yonezawa, T., Kurusu, S., Hasegawa, Y., Brachvogel, B., P\u00f6schl, E. and Kawaminami, M. 2012. Loss of maternal annexin A5 increases the likelihood of placental platelet thrombosis and foetal loss. <i>Sci. Rep.<\/i> 2: 827.","DOI":"10.1038\/srep00827"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. Yao, B. and Kawaminami, M. 2008. Stimulation of annexin A5 expression by gonadotropin releasing hormone (GnRH) in the Leydig cells of rats. <i>J. Reprod. Dev.<\/i> 54: 259\u2013264.","DOI":"10.1262\/jrd.20039"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/80\/1\/80_17-0569\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,7]],"date-time":"2019-10-07T13:20:43Z","timestamp":1570454443000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/80\/1\/80_17-0569\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.17-0569","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}