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Psychiatry<\/i> 87: 29\u201336.","DOI":"10.1136\/jnnp-2014-309831"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Santhosh, S. R., Parida, M. M., Dash, P. K., Pateriya, A., Pattnaik, B., Pradhan, H. K., Tripathi, N. K., Ambuj, S., Gupta, N., Saxena, P. and Lakshmana Rao, P. V. 2007. Development and evaluation of SYBR Green I-based one-step real-time RT-PCR assay for detection and quantitation of Japanese encephalitis virus. <i>J. Virol. Methods<\/i> 143: 73\u201380.","DOI":"10.1016\/j.jviromet.2007.02.011"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Shu, P. Y., Chang, S. F., Kuo, Y. C., Yueh, Y. Y., Chien, L. J., Sue, C. L., Lin, T. H. and Huang, J. H. 2003. Development of group- and serotype-specific one-step SYBR green I-based real-time reverse transcription-PCR assay for dengue virus. <i>J. Clin. Microbiol.<\/i> 41: 2408\u20132416.","DOI":"10.1128\/JCM.41.6.2408-2416.2003"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Sofroniew, M. 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