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Amimoto,                A.,              Noguchi, M.,                Hachimura,              H., Suzuki,                T. and                Nakano,            M.          1999. Survey of the incidence of calculus deposition and            periodontal disease in cats. <i>J. Anim. Clin.              Med.<\/i>          8: 99\u2013102."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Culham,              N. and                Rawlings, J.              M.          1998. Oral malodor and its relevance to periodontal disease in            the dog. <i>J. Vet. Dent.<\/i>          15: 165\u2013168.","DOI":"10.1177\/089875649801500401"},{"key":"3","unstructured":"3. Dec,              M. and                Puchalski,              A.          2008. Use of oromucosally administered IFN-\u03b1 in the prevention            and treatment of animal diseases. <i>Pol. J. Vet.              Sci.<\/i>          11: 171\u2013182."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Eubanks, D.                L.          2010. Periodontal disease assessment.              <i>J. Vet. Dent.<\/i>          27: 58\u201360.","DOI":"10.1177\/089875641002700112"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Gorrel,              C.          2004. Periodontal disease. pp. 87\u2013110. <i>In<\/i>: Veterinary          Dentistry for the General Practitioner, Elsevier Health Science, London.","DOI":"10.1016\/B978-0-7020-2747-5.50012-8"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Guarda,              G., Braun,                M.,              Staehli, F.,                Tardivel,              A., Mattmann,                C.,              F\u00f6rster, I.,                Farlik, M.,                Decker, T.,                Du Pasquier, R.              A., Romero,                P. and                Tschopp,            J.          2011. Type I interferon inhibits interleukin-1 production and            inflammasome activation. <i>Immunity<\/i>          34: 213\u2013223.","DOI":"10.1016\/j.immuni.2011.02.006"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Hardham,                J., Dreier,                K., Wong,                J.,                Sfintescu,              C. and Evans,                R. T.          2005. Pigmented-anaerobic bacteria associated with canine            periodontitis. <i>Vet. Microbiol.<\/i>          106: 119\u2013128.","DOI":"10.1016\/j.vetmic.2004.12.018"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Holmstrom, S.                E., Bellows,                J., Juriga,                S.,              Knutson, K.,                Niemiec, B.              A., Perrone,                J., American            Veterinary Dental College          2013. 2013 AAHA dental care guidelines for dogs and            cats. <i>J. Am. Anim. Hosp. Assoc.<\/i>          49: 75\u201382.","DOI":"10.5326\/JAAHA-MS-4013"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ito,              A., Isogai,                E.,                Yoshioka,              K., Sato,                K., Himeno,                N. and                Gotanda,            T.          2010. Ability of orally administered IFN-\u03b14 to inhibit            naturally occurring gingival inflammation in dogs. <i>J.              Vet. Med. Sci.<\/i>          72: 1145\u20131151.","DOI":"10.1292\/jvms.09-0201"},{"key":"10","unstructured":"10. Malireddi, R.                K. and Kanneganti,                T. D.          2013. Role of type I interferons in inflammasome activation,            cell death, and disease during microbial infection.              <i>Front. Cell. Infect. Microbiol.<\/i>          3: 77."},{"key":"11","unstructured":"11. Miyazaki,                H., Arao,                M.,              Okamura, K.,                Kawaguchi,              Y., Toyofuku,                A., Hoshi,                K. and                Yaegaki,            K.          1999. Tentative classification for halitosis patients and its            treatment needs. <i>Niigata<\/i>. <i>Dent.              J.<\/i>          29: 11\u201315."},{"key":"12","unstructured":"12. Niemiec, B.                A., Gawor,                J., Nemec,                A., Clarke,                D., Tutt,                D., Gioso,                M.,              Stegall, P.,                Chandler,              M.,              Morgenegg,            G., Jouppi,                R. and                Stewart,            K.          2017. World Small Animal Veterinary Association Global Dental Guidelines,            https:\/\/www.wsava.org\/WSAVA\/media\/Documents\/Guidelines\/Dental-Guidleines-for-endorsement_0.pdf          [accessed on January 5, 2019]."},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. P\u00e9rez-Salcedo,                L.,              Herrera, D.,                Esteban-Saltiveri,              D., Le\u00f3n,                R.,                Jeusette,              I., Torre,                C.,                O\u2019Connor,              A., Gonz\u00e1lez,                I. and                Gonz\u00e1lez,              I.          2013. Isolation and identification of Porphyromonas spp. and            other putative pathogens from cats with periodontal disease.              <i>J. Vet. Dent.<\/i>          30: 208\u2013213.","DOI":"10.1177\/089875641303000402"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Senhorinho, G. N.                A., Nakano,                V., Liu,                C., Song,                Y.,                Finegold, S.              M. and Avila-Campos,                M. J.          2011. Detection of <i>Porphyromonas gulae<\/i> from            subgingival biofilms of dogs with and without periodontitis.              <i>Anaerobe<\/i>          17: 257\u2013258.","DOI":"10.1016\/j.anaerobe.2011.06.002"},{"key":"15","unstructured":"15. Ueda,                I.          1990. Ekigaku. pp. 59\u201388. <i>In<\/i>: Koukuueiseigaku (Nakao, S.,          Iizuka, K., Ueda, I. and Konishi, K. eds.), Quintessence Publishing, Tokyo (in          Japanse)."},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Yamaki,              S.,              Hachimura,            H., Wada,                S., Oonari,                A., Ogawa,                M.,              Kanegae, S.            and Amimoto,            A.          2017. Long-term follow-up study after the administration of            canine interferon-\u03b1 preparation for gingivitis in dogs.              <i>J. Jpn. Med. 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