{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T22:08:29Z","timestamp":1774649309247,"version":"3.50.1"},"reference-count":10,"publisher":"Japanese Society of Veterinary Science","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2022]]},"DOI":"10.1292\/jvms.21-0346","type":"journal-article","created":{"date-parts":[[2021,12,5]],"date-time":"2021-12-05T22:08:20Z","timestamp":1638742100000},"page":"36-39","source":"Crossref","is-referenced-by-count":3,"title":["Lokivetmab improved pruritus in a dog with cutaneous epitheliotropic lymphoma"],"prefix":"10.1292","volume":"84","author":[{"given":"Kiyohiko","family":"INAI","sequence":"first","affiliation":[{"name":"Sakura Animal Hospital, 5-3-1 Kasuga, Toyonaka, Osaka 560-0052, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita","family":"KITAGAWA","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine and Integrated Biology, College of Veterinary Medicine, Michigan State University, 736 Wilson Rd, East Lansing, MI 48824, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mami","family":"MURAKAMI","sequence":"additional","affiliation":[{"name":"Joint Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiroh","family":"IWASAKI","sequence":"additional","affiliation":[{"name":"Pet Skin Clinic, 59-5 Fukaehama, Higashinada, Kobe, Hyogo 658-0023, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Chan, C. M., Frimberger, A. E. and Moore, A. S. 2018. Clinical outcome and prognosis of dogs with histopathological features consistent with epitheliotropic lymphoma: a retrospective study of 148 cases (2003\u20132015). <i>Vet. Dermatol.<\/i> 29: 154\u2013e59.","DOI":"10.1111\/vde.12504"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Fontaine, J., Heimann, M. and Day, M. J. 2010. Canine cutaneous epitheliotropic T-cell lymphoma: a review of 30 cases. <i>Vet. Dermatol.<\/i> 21: 267\u2013275.","DOI":"10.1111\/j.1365-3164.2009.00793.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Gonzales, A. J., Humphrey, W. R., Messamore, J. E., Fleck, T. J., Fici, G. J., Shelly, J. A., Teel, J. F., Bammert, G. F., Dunham, S. A., Fuller, T. E. and McCall, R. B. 2013. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. <i>Vet. Dermatol.<\/i> 24: 48\u201353.e11, 2.","DOI":"10.1111\/j.1365-3164.2012.01098.x"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Hill, P. B., Lau, P. and Rybnicek, J. 2007. Development of an owner-assessed scale to measure the severity of pruritus in dogs. <i>Vet. Dermatol.<\/i> 18: 301\u2013308.","DOI":"10.1111\/j.1365-3164.2007.00616.x"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Holtermann, N., Kiupel, M., Kessler, M., Teske, E., Betz, D. and Hirschberger, J. 2016. Masitinib monotherapy in canine epitheliotropic lymphoma. <i>Vet. Comp. Oncol.<\/i> 14 Suppl 1: 127\u2013135.","DOI":"10.1111\/vco.12157"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Ignatenko, N., Gonzales, A. J., Messamore, J. E., Hirschberger, J., Udraite-Vovk, L., Boehm, T. M. S. A., Troedson, K., Fejos, C. and Mueller, R. S. 2020. Serum concentrations of IL-31 in dogs with nonpruritic mast cell tumours or lymphoma. <i>Vet. Dermatol.<\/i> 31: 466\u2013e124.","DOI":"10.1111\/vde.12887"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Michels, G. M., Ramsey, D. S., Walsh, K. F., Martinon, O. M., Mahabir, S. P., Hoevers, J. D., Walters, R. R. and Dunham, S. A. 2016. A blinded, randomized, placebo-controlled, dose determination trial of lokivetmab (ZTS-00103289), a caninized, anti-canine IL-31 monoclonal antibody in client owned dogs with atopic dermatitis. <i>Vet. Dermatol.<\/i> 27: 478\u2013e129.","DOI":"10.1111\/vde.12376"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Moore, P. F., Affolter, V. K., Graham, P. S. and Hirt, B. 2009. Canine epitheliotropic cutaneous T-cell lymphoma: an investigation of T-cell receptor immunophenotype, lesion topography and molecular clonality. <i>Vet. Dermatol.<\/i> 20: 569\u2013576.","DOI":"10.1111\/j.1365-3164.2009.00814.x"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Ohmatsu, H., Sugaya, M., Suga, H., Morimura, S., Miyagaki, T., Kai, H., Kagami, S., Fujita, H., Asano, Y., Tada, Y., Kadono, T. and Sato, S. 2012. Serum IL-31 levels are increased in patients with cutaneous T-cell lymphoma. <i>Acta Derm. Venereol.<\/i> 92: 282\u2013283.","DOI":"10.2340\/00015555-1345"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Singer, E. M., Shin, D. B., Nattkemper, L. A., Benoit, B. M., Klein, R. S., Didigu, C. A., Loren, A. W., Dentchev, T., Wysocka, M., Yosipovitch, G. and Rook, A. H. 2013. IL-31 is produced by the malignant T-cell population in cutaneous T-Cell lymphoma and correlates with CTCL pruritus. <i>J. Invest. Dermatol.<\/i> 133: 2783\u20132785.","DOI":"10.1038\/jid.2013.227"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/84\/1\/84_21-0346\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,8]],"date-time":"2022-01-08T03:39:37Z","timestamp":1641613177000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/84\/1\/84_21-0346\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.21-0346","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022]]},"article-number":"21-0346"}}