{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T19:02:36Z","timestamp":1757617356321,"version":"3.44.0"},"reference-count":24,"publisher":"Japanese Society of Veterinary Science","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2025]]},"DOI":"10.1292\/jvms.25-0198","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T22:07:43Z","timestamp":1752703663000},"page":"1100-1106","source":"Crossref","is-referenced-by-count":0,"title":["Pre-contrast hyperattenuating metastatic lymph node on computed tomography due to iodide accumulation in a dog with thyroid carcinoma"],"prefix":"10.1292","volume":"87","author":[{"given":"Sang-Kwon","family":"LEE","sequence":"first","affiliation":[{"name":"Department of Veterinary Medical Imaging, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su-Min","family":"BAEK","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Kyu","family":"PARK","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsu","family":"KANG","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"JANG","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kija","family":"LEE","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medical Imaging, College of Veterinary Medicine, Kyungpook National University, Daegu, Republic of Korea"},{"name":"Institute for Veterinary Biomedical Science, Kyungpook National University, Daegu, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Amor\u00f3s O, Espada Y, Vila A, Jim\u00e9nez A, Novellas R.  2021. Pre-contrast CT attenuation of the thyroid gland is lower in brachycephalic dogs versus non-brachycephalic dogs. <i>Vet Radiol Ultrasound<\/i> 62: 54\u201360.","DOI":"10.1111\/vru.12922"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Athey JM, Vieson MD, Bailey K, Rudmann D, Baumgartner WA, Selting KA.  2024. Canine thyroid carcinomas: A review with emphasis on comparing the compact subtype of follicular thyroid carcinomas and medullary thyroid carcinomas. <i>Vet Pathol<\/i> 61: 7\u201319.","DOI":"10.1177\/03009858231177225"},{"key":"3","unstructured":"3. Belotta AF, Sukut S, Lowe C, Waldner C, Randall EK, MacDonald VS, Gagnon J, Mayer MN.  2022. Computed tomography features of presumed normal mandibular and medial retropharyngeal lymph nodes in dogs. <i>Can J Vet Res<\/i> 86: 27\u201334."},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Cho SJ, Suh CH, Baek JH, Chung SR, Choi YJ, Lee JH.  2019. Diagnostic performance of CT in detection of metastatic cervical lymph nodes in patients with thyroid cancer: a systematic review and meta-analysis. <i>Eur Radiol<\/i> 29: 4635\u20134647.","DOI":"10.1007\/s00330-019-06036-8"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Eisenkraft BL, Som PM.  1999. The spectrum of benign and malignant etiologies of cervical node calcification. <i>AJR Am J Roentgenol<\/i> 172: 1433\u20131437.","DOI":"10.2214\/ajr.172.5.10227533"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Gegin S, Pazarl\u0131 AC, \u00d6zdemir B, \u00d6zdemir L, Aksu EA.  2024. The effect of hounsfield unit value on the differentiation of malignant\/benign mediastinal lymphadenopathy and masses diagnosed by endobronchial ultrasonography. <i>Cancer Manag Res<\/i> 16: 1013\u20131020.","DOI":"10.2147\/CMAR.S473653"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Goldschmidt S, Stewart N, Ober C, Bell C, Wolf-Ringwall A, Kent M, Lawrence J.  2023. Contrast-enhanced and indirect computed tomography lymphangiography accurately identifies the cervical lymphocenter at risk for metastasis in pet dogs with spontaneously occurring oral neoplasia. <i>PLoS One<\/i> 18: e0282500.","DOI":"10.1371\/journal.pone.0282500"},{"key":"8","unstructured":"8. Hayashi T, Tanaka R, Taira S, Koyama J, Katsura K, Kobayashi F.  2003. Non-contrast-enhanced CT findings of high attenuation within metastatic cervical lymph nodes in patients with stage I or II tongue carcinoma during a follow-up period. <i>AJNR Am J Neuroradiol<\/i> 24: 1330\u20131333."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Kim SH, Lee KN, Kang EJ, Kim DW, Hong SH.  2012. Hounsfield units upon PET\/CT are useful in evaluating metastatic regional lymph nodes in patients with oesophageal squamous cell carcinoma. <i>Br J Radiol<\/i> 85: 606\u2013612.","DOI":"10.1259\/bjr\/73516936"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Kogai T, Brent GA.  2012. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. <i>Pharmacol Ther<\/i> 135: 355\u2013370.","DOI":"10.1016\/j.pharmthera.2012.06.007"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Lee JY, Kim YH, Park YJ, Park SB, Chung HW, Zo JI, Shim YM, Lee KS, Choi JY.  2019. Improved detection of metastatic lymph nodes in oesophageal squamous cell carcinoma by combined interpretation of fluorine-18-fluorodeoxyglucose positron-emission tomography\/computed tomography. <i>Cancer Imaging<\/i> 19: 40.","DOI":"10.1186\/s40644-019-0225-5"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Menghini TL, Schwarz T, Dancer S, Gray C, MacGillivray T, Blacklock KLB.  2023. Contrast-enhanced CT predictors of lymph nodal metastasis in dogs with oral melanoma. <i>Vet Radiol Ultrasound<\/i> 64: 694\u2013705.","DOI":"10.1111\/vru.13254"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Milovancev M, Nemanic S, Bobe G.  2017. Computed tomographic assessment of sternal lymph node dimensions and attenuation in healthy dogs. <i>Am J Vet Res<\/i> 78: 289\u2013294.","DOI":"10.2460\/ajvr.78.3.289"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Nemanic S, Nelson NC.  2012. Ultrasonography and noncontrast computed tomography of medial retropharyngeal lymph nodes in healthy cats. <i>Am J Vet Res<\/i> 73: 1377\u20131385.","DOI":"10.2460\/ajvr.73.9.1377"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Roh YH, Chung SR, Baek JH, Choi YJ, Sung TY, Song DE, Kim TY, Lee JH.  2023. Validation of CT-based risk stratification system for lymph node metastasis in patient with thyroid cancer. <i>Korean J Radiol<\/i> 24: 1028\u20131037.","DOI":"10.3348\/kjr.2023.0308"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Skinner OT, Boston SE, Giglio RF, Whitley EM, Colee JC, Porter EG.  2018. Diagnostic accuracy of contrast-enhanced computed tomography for assessment of mandibular and medial retropharyngeal lymph node metastasis in dogs with oral and nasal cancer. <i>Vet Comp Oncol<\/i> 16: 562\u2013570.","DOI":"10.1111\/vco.12415"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Skinner OT, Kim DY, Story AL, Karnia JJ, Selmic LE, Lapsley JM, Dornbusch JA, Johnson C, Oblak ML, McKenna C, Garrett CJ, Hoehn MM, Mickelson MA.  2024. Prospective assessment of canine thyroid cancer-part I: nodal metastatic rate and impact of nodal immunohistochemistry in 70 dogs. <i>J Am Vet Med Assoc<\/i> 262: 1\u201310.","DOI":"10.2460\/javma.24.03.0223"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Skinner OT, Souza CHM, Kim DY.  2021. Metastasis to ipsilateral medial retropharyngeal and deep cervical lymph nodes in 22 dogs with thyroid carcinoma. <i>Vet Surg<\/i> 50: 150\u2013157.","DOI":"10.1111\/vsu.13549"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Soultani C, Patsikas MN, Mayer M, Kazakos GM, Theodoridis TD, Vignoli M, Ilia TSM, Karagiannopoulou M, Ilia GM, Tragoulia I, Angelou VN, Chatzimisios K, Tselepidis S, Papadopoulou PL, Papazoglou LG.  2021. Contrast enhanced computed tomography assessment of superficial inguinal lymph node metastasis in canine mammary gland tumors. <i>Vet Radiol Ultrasound<\/i> 62: 557\u2013567.","DOI":"10.1111\/vru.13002"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Taeymans O, Schwarz T, Duchateau L, Barberet V, Gielen I, Haskins M, Van Bree H, Saunders JH.  2008. Computed tomographic features of the normal canine thyroid gland. <i>Vet Radiol Ultrasound<\/i> 49: 13\u201319.","DOI":"10.1111\/j.1740-8261.2007.00310.x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Urata M, Kijima Y, Hirata M, Shinden Y, Arima H, Nakajo A, Koriyama C, Arigami T, Uenosono Y, Okumura H, Maemura K, Ishigami S, Yoshinaka H, Natsugoe S.  2014. Computed tomography Hounsfield units can predict breast cancer metastasis to axillary lymph nodes. <i>BMC Cancer<\/i> 14: 730.","DOI":"10.1186\/1471-2407-14-730"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. van der Laan L, Le Roux C.  2024. Malignant melanoma and lymph node metastases appearing as hyperattenuating masses on computed tomography in a dog. <i>Vet Radiol Ultrasound<\/i> 65: 339\u2013343.","DOI":"10.1111\/vru.13366"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Wang ZL, Yan Y, Li XT, Li YL, Li ZW, Sun YS.  2023. Usefulness of attenuation value on computed tomography plain scan for diagnosing enlarged mediastinal lymph nodes metastases. <i>Quant Imaging Med Surg<\/i> 13: 5759\u20135769.","DOI":"10.21037\/qims-22-1305"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Willcox JL, Spriet M, Zwingenberger AL, Phillips KL, Burton JH, Skorupski KA, Hansen KS, Affolter VK, Woolard KD, Beylin D, Giuffrida MA.  2021. Evaluation of accuracy for <sup>18<\/sup> F-FDG positron emission tomography and computed tomography for detection of lymph node metastasis in canine oral malignant melanoma. <i>Vet Comp Oncol<\/i> 19: 463\u2013472.","DOI":"10.1111\/vco.12651"}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/87\/9\/87_25-0198\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T03:17:56Z","timestamp":1757128676000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/jvms\/87\/9\/87_25-0198\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":24,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.25-0198","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"type":"print","value":"0916-7250"},{"type":"electronic","value":"1347-7439"}],"subject":[],"published":{"date-parts":[[2025]]},"article-number":"25-0198"}}