{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:31:19Z","timestamp":1758396679133},"reference-count":26,"publisher":"Japanese Society of Veterinary Science","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Vet. Med. Sci.","The Journal of Veterinary Medical Science"],"published-print":{"date-parts":[[2007]]},"DOI":"10.1292\/jvms.69.103","type":"journal-article","created":{"date-parts":[[2007,3,6]],"date-time":"2007-03-06T05:35:05Z","timestamp":1173159305000},"page":"103-109","source":"Crossref","is-referenced-by-count":20,"title":["Evaluation of the Low Dose Level of a Heat-Killed and Dried Cell Preparation of Enterococcus faecalis to Prevent Porcine Edema Disease Using Experimental Infection Model with Enterotoxcemic Escherichia coli in Weaning Pigs"],"prefix":"10.1292","volume":"69","author":[{"given":"Takamitsu","family":"TSUKAHARA","sequence":"first","affiliation":[{"name":"Laboratory of Animal Science, Kyoto Prefectural University"},{"name":"Kyoto Institute of Nutrition & Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"INOUE","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Science, Kyoto Prefectural University"},{"name":"Kyoto Institute of Nutrition & Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"NAKANISHI","sequence":"additional","affiliation":[{"name":"KYODOKEN Institute"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keizo","family":"NAKAYAMA","sequence":"additional","affiliation":[{"name":"Kyoto Institute of Nutrition & Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noritaka","family":"MATSUBARA","sequence":"additional","affiliation":[{"name":"Combi Corporation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunari","family":"USHIDA","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Science, Kyoto Prefectural University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"122","reference":[{"key":"1","unstructured":"1. Arima, M. 2004. Differentiation of eosinophils in allergy. Igakuno Ayumi 211: 701-706 (in Japanese)."},{"key":"2","unstructured":"2. Bertschinger, H. U. and Gyles, C. L. 1994. Oedema disease of pigs. pp. 193-219. <i>In<\/i>: <i>Escherichia coli<\/i> in Domestic Animals (Gyles, C. L. ed.), CAB International, Wallingford."},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Bosworth, B. T., Dean-Nystrom, E. A., Casey, T. A. and Neibergs, H. L. 1998. Differentiation of F18ab<sup>+<\/sup> from F18ac<sup>+<\/sup> <i>Escherichia coli<\/i> by single-strand conformational polymorphism analysis of the major fimbrial subunit gene (<i>fedA<\/i>). Clin. Diagn. Lab. Immunol. 5: 299-302.","DOI":"10.1128\/CDLI.5.3.299-302.1998"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.11.5134-5146.2003"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Fukuyama, M., Furuhata, K., Oonaka, K., Yakiwara, R., Koizumi, T., Hara, M., Dogasaki, C. and Watanabe, T. 2003. Isolation and serotyping of vero toxin-producing <i>Escherichia coli<\/i> (VTEC) from pig. Kansensyogaku-Zasshi 77: 1032-1039 (in Japanese with English summary).","DOI":"10.11150\/kansenshogakuzasshi1970.77.1032"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2323\/jgam.51.257"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.10.4200-4204.2000"},{"key":"8","unstructured":"8. Kojima, S. and Okamoto, Y. 1997. NIH Image Shin-Kouza, Youdosya, Tokyo (in Japanese)."},{"key":"9","unstructured":"9. Kuramoto, Y., Kobayashi, N., Otsuka, M., Yamaguchi, K., Kaneko, H., Kan, T., Bukawa, W. and Suzuki, T. 2004. The effect of the heat-killed Enterococci, EC-12, on a host defense mechanism in mice after infection with <i>Listeria monocytogenes<\/i>. J. New Rem. Clin. 53: 298-308 (in Japanese with English summary)."},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Nanno, M., Shimizu, T., Mike, A., Ohwaki, M. and Mutai, M. 1988. Role of macrophages in serum colony-stimulating factor induction by <i>Lactobacillus casei<\/i> in mice. Infect. Immun. 56: 357-362.","DOI":"10.1128\/IAI.56.2.357-362.1988"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Nowak-Wegrzyn, A. 2003. Future approaches to food allergy. Pediatrics 111: 1672-1680.","DOI":"10.1542\/peds.111.4.829"},{"issue":"19","key":"12","doi-asserted-by":"crossref","first-page":"5636","DOI":"10.1128\/jb.178.19.5636-5643.1996","volume":"178","year":"1996","journal-title":"J. Bacteriol.","ISSN":"http:\/\/id.crossref.org\/issn\/0021-9193","issn-type":"print"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Shu, Q., Qu, F. and Gill, H. S. 2001. Probiotic treatment using <i>Bifidobacterium lactis<\/i> HN019 reduces weanling diarrhea associated with rotavirus and <i>Escherichia coli<\/i> infection in a piglet model. J. Pediatr. Gastroenterol. Nutr. 33: 171-177.","DOI":"10.1097\/00005176-200108000-00014"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Terada, A., Bukawa, W., Kan, T. and Mitsuoka, T. 2004. Effects of the consumption of heat-killed <i>Enterococcus faecalis<\/i> EC-12 preparation on microbiota and metabolic activity of the feces in healthy adults. Microb. Ecol. Health Dis. 16: 188-194.","DOI":"10.1080\/08910600410017346"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1080\/08910600510044507"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.65.301"},{"issue":"6","key":"17","doi-asserted-by":"crossref","first-page":"414","DOI":"10.3177\/jnsv.49.414","volume":"49","author":"TSUKAHARA T","year":"2003","journal-title":"J. Nutr. Sci. Vitaminol.","ISSN":"http:\/\/id.crossref.org\/issn\/0301-4800","issn-type":"print"},{"key":"18","unstructured":"18. Tsukahara, T., Nakanishi, N., Matsubara, N., Itoh, M. and Ushida, K. 2006. The effect of <i>Enterococcus faecalis<\/i> cell preparation (EC-12) against the diarrhea in the nursing and weaning piglets under the clinical condition. Proc. Jpn. Pig Vet. Soc. 48: 19-23 (in Japanese)."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Tsukahara, T., Nakanishi, N., Nakayama, K., Matsubara, N. and Ushida, K. 2005. Experimental infection of enterotoxemic <i>Escherichia coli<\/i> associated with porcine edema disease and its pathologic characteristics in the intestine. J. Vet. Med. Sci. 67: 1169-1173.","DOI":"10.1292\/jvms.67.1167"},{"key":"20","unstructured":"20. Tsukahara, T., Nakanishi, N., Shiga, A., Matsubara, N. and Ushida, K. 2004. <i>Enterococcus faecalis<\/i> cell preparation (EC-12) significantly alleviating diarrhea diseases in nursing piglets may replace antimicrobials. Reprod. Nutr. Dev. 44: S49."},{"issue":"1","key":"21","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1348-0421.2003.tb02786.x","volume":"47","author":"UEMURA R","year":"2003","journal-title":"Microbiol. Immunol.","ISSN":"http:\/\/id.crossref.org\/issn\/0385-5600","issn-type":"print"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.66.899"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Ushida, K. and Sakata, T. 1998. Effect of pH on oligosaccharide fermentation by porcine cecal digesta. Anim. Sci. Technol. (Jpn.) 69: 100-107.","DOI":"10.2508\/chikusan.69.100"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Watanabe, K. and Yoshiura, N. 2001. Economical losses and effects of the strategies against edema disease in one pig farm. J. Vet. Epidemiol. 5: 25-29 (in Japanese with English summary).","DOI":"10.2743\/jve.5.25"},{"key":"25","unstructured":"25. Yanai, H. 1998. Excel-toukei. Seiunsya, Tokyo (in Japanese)."},{"key":"26","unstructured":"26. Yuji, H., Tsuji, A. and Sueyoshi, M. 2000. Control measure of edema disease in pigs with probiotics and antibiotics. J. Vet. Clin. 47: 423-428 (in Japanese with English summary)."}],"container-title":["Journal of Veterinary Medical Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jvms\/69\/2\/69_2_103\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T01:59:05Z","timestamp":1617069545000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jstage.jst.go.jp\/article\/jvms\/69\/2\/69_2_103\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":26,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1292\/jvms.69.103","relation":{},"ISSN":["0916-7250","1347-7439"],"issn-type":[{"value":"0916-7250","type":"print"},{"value":"1347-7439","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}