{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:51:09Z","timestamp":1787021469661,"version":"build-2736575974"},"reference-count":12,"publisher":"Japanese Society of Toxicologic Pathology","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Toxicol Pathol"],"published-print":{"date-parts":[[2016]]},"DOI":"10.1293\/tox.2016-0017","type":"journal-article","created":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T18:56:34Z","timestamp":1464288994000},"page":"261-264","source":"Crossref","is-referenced-by-count":3,"title":["Acute alloxan toxicity causes granulomatous tubulointerstitial nephritis with severe mineralization"],"prefix":"10.1293","volume":"29","author":[{"given":"Lianshan","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Pathology, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang 050017, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yui","family":"Terayama","sequence":"additional","affiliation":[{"name":"Laboratory of Pathology, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiki","family":"Nishimoto","sequence":"additional","affiliation":[{"name":"Laboratory of Clinicopathological Therapeutics, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hirokoshinkai, Kure, Hiroshima 737-0112, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Kodama","sequence":"additional","affiliation":[{"name":"Laboratory of Clinicopathological Therapeutics, Faculty of Pharmaceutical Sciences, Hiroshima International University, 5-1-1 Hirokoshinkai, Kure, Hiroshima 737-0112, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyokazu","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Laboratory of Pathology, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"121","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Evan AP, Mong SA, Connors BA, Aronoff GR, and Luft FC. The effect of alloxan, and alloxan-induced diabetes on the kidney. Anat Rec. 208: 33\u201347. 1984.","DOI":"10.1002\/ar.1092080105"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Vargas L, Friederici HH, and Maibenco HC. Cortical sponge kidneys induced in rats by alloxan. Diabetes. 19: 33\u201344. 1970.","DOI":"10.2337\/diab.19.1.33"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Bruckmann G, and Wertheimer E. Alloxan studies; the action of alloxan homologues and related compounds. J Biol Chem. 168: 241\u2013256. 1947.","DOI":"10.1016\/S0021-9258(17)35111-6"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. de Water R, Noordermeer C, Houtsmuller AB, Nigg AL, Stijnen T, Schr\u00f6der FH, and Kok DJ. Role of macrophages in nephrolithiasis in rats: an analysis of the renal interstitium. Am J Kidney Dis. 36: 615\u2013625. 2000.","DOI":"10.1053\/ajkd.2000.16203"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Boev\u00e9 ER, Ketelaars GA, Vermeij M, Cao LC, Schr\u00f6der FH, and De Bruijn WC. An ultrastructural study of experimentally induced microliths in rat proximal and distal tubules. J Urol. 149: 893\u2013899. 1993.","DOI":"10.1016\/S0022-5347(17)36254-7"},{"key":"6","unstructured":"6. de Bruijn WC, Boev\u00e9 ER, van Run PR, van Miert PP, Romijn JC, Verkoelen CF, Cao LC, and Schr\u00f6der FH. Etiology of experimental calcium oxalate monohydrate nephrolithiasis in rats. Scanning Microsc. 8: 541\u2013549, discussion 549\u2013550. 1994."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Lieske JC, Spargo BH, and Toback FG. Endocytosis of calcium oxalate crystals and proliferation of renal tubular epithelial cells in a patient with type 1 primary hyperoxaluria. J Urol. 148: 1517\u20131519. 1992.","DOI":"10.1016\/S0022-5347(17)36954-9"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Khan SR. Calcium oxalate crystal interaction with renal tubular epithelium, mechanism of crystal adhesion and its impact on stone development. Urol Res. 23: 71\u201379. 1995.","DOI":"10.1007\/BF00307936"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Mann PC, Vahle J, Keenan CM, Baker JF, Bradley AE, Goodman DG, Harada T, Herbert R, Kaufmann W, Kellner R, Nolte T, Rittinghausen S, and Tanaka T. International harmonization of toxicologic pathology nomenclature: an overview and review of basic principles. Toxicol Pathol. 40(Suppl): 7S\u201313S. 2012.","DOI":"10.1177\/0192623312438738"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Elsner M, Tiedge M, Guldbakke B, Munday R, and Lenzen S. Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan. Diabetologia. 45: 1542\u20131549. 2002.","DOI":"10.1007\/s00125-002-0955-x"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Weaver DC, McDaniel ML, and Lacy PE. Alloxan uptake by isolated rat islets of Langerhans. Endocrinology. 102: 1847\u20131855. 1978.","DOI":"10.1210\/endo-102-6-1847"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12. Lenzen S. The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia. 51: 216\u2013226. 2008.","DOI":"10.1007\/s00125-007-0886-7"}],"container-title":["Journal of Toxicologic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tox\/29\/4\/29_2016-0017\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T14:23:42Z","timestamp":1656599022000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/tox\/29\/4\/29_2016-0017\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.1293\/tox.2016-0017","relation":{},"ISSN":["0914-9198","1881-915X"],"issn-type":[{"value":"0914-9198","type":"print"},{"value":"1881-915X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}