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It highlights the discoveries and also includes details of the failed attempts to locate the cause and identify a solution to the ancient mysterious disease which became known to all as diabetes mellitus. Early remedies and treatments are included. The article tells how for many centuries individuals suffered from the debilitating complaint with very little offered in terms of treatment or relief. Eventually the pancreas was identified as the causative organ and, some time later, animal experimentation resulted in the abstraction of the substance insulin. The article concludes with Frederick Banting and John Macleod being awarded the Nobel Prize in 1923 for their revolutionary discovery of insulin. <\/jats:p>","DOI":"10.12968\/bjon.2003.12.18.11775","type":"journal-article","created":{"date-parts":[[2014,5,23]],"date-time":"2014-05-23T14:09:54Z","timestamp":1400854194000},"page":"1091-1095","source":"Crossref","is-referenced-by-count":24,"title":["A history of diabetes: from antiquity to discovering insulin"],"prefix":"10.12968","volume":"12","author":[{"given":"Kathryn M","family":"King","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg","family":"Rubin","sequence":"additional","affiliation":[{"name":"Primary Care, University of Sunderland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5130","reference":[{"key":"p_42","volume-title":"Paracelsus in the 16th century"},{"key":"p_72","volume-title":"tells us that the first and salient","author":"Gull","year":"1886"},{"key":"p_94","volume-title":"who","author":"French","year":"1893"},{"key":"p_100","doi-asserted-by":"publisher","DOI":"10.7208\/chicago\/9780226075631.001.0001"},{"key":"p_101","volume-title":"International Islet Transplant Registry","author":"Brar D","year":"2001"},{"key":"p_102","volume-title":"International Islet Transplant Registry","author":"Bretzel RG","year":"2001"},{"key":"p_103","volume-title":"Diabetes timeline. 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